Results 241 to 250 of about 905,740 (294)

AFF4 Loss Compromises Osteogenesis of Orofacial Mesenchymal Stem Cells During Alveolar Bone Repair via AMPK‐Mediated Mitophagy

Cell Proliferation, EarlyView.
Compromised alveolar socket healing following tooth extraction upon Aff4 knockout is caused by suppressed osteogenic capacity of orofacial mesenchymal stem cells, which results from defective AMPK‐mediated mitophagy. ABSTRACT Repair of maxillofacial bone defects presents significant clinical challenges.
Li Zhu, Shuo Chen, Guowen Luo, Tingyue Zhang, Hengyi Lin, Yiling Chen, Chenchen Zhou, Shujuan Zou   +7 more
wiley   +1 more source

Dynamics of BMP signaling and stable gene expression in the early Drosophila embryo. [PDF]

Biol Open
Al Asafen H, Beseli A, Chen HY, Hiremath S, Williams CM, Reeves GT.   +5 more
europepmc   +1 more source

Sclerostin regulates bone morphogenetic protein (BMP) bioavailability through interactions with BMP complexes and fibrillin microfibrils

The FEBS Journal, EarlyView.
Sclerostin (SOST) is a multifunctional extracellular modulator of BMP and Wnt signaling. SOST binds with high affinity to fibrillin‐1 and fibrillin‐2, localizing it to fibrillin microfibrils and regulating its extracellular bioavailability. Fibrillin‐bound SOST cannot engage BMP‐7 prodomain (PD) complexes, revealing a competitive mechanism that ...
Annkatrin Correns, Fady Marcous, Steffen Lütke, Matthias Mörgelin, Philipp Barnowski, Ariane G. Furlan, Nathalie H. Schröder, Bodo Levkau, Sarah Riek, Martin Mollenhauer, Manuel Koch, Gerhard Sengle   +11 more
wiley   +1 more source

Discoidin domain receptor 2 is an important modulator of BMP signaling during heterotopic bone formation. [PDF]

Bone Res
Wu F, Ge C, Pan H, Han Y, Mishina Y, Kaartinen V, Franceschi RT.   +6 more
europepmc   +1 more source

Correction: Optimizing Nodal, Wnt and BMP signaling pathways for robust and efficient differentiation of human induced pluripotent stem cells to intermediate mesoderm cells. [PDF]

Front Cell Dev Biol
Magro-Lopez E, Vazquez-Alejo E, Espinar-Buitrago MS, Muñoz-Fernández MÁ.   +3 more
europepmc   +1 more source

The anti-neural role of BMP signaling is a side effect of its global function in dorsoventral patterning

Knabl P, Ordoñez JF, Montenegro Cabrera JD, Wollesen T, Genikhovich G.   +4 more
europepmc   +1 more source

Regulatory role of CD177+ neutrophils in BMP signaling pathway and its implications for inflammatory bowel disease, sepsis, and intestinal tumors. [PDF]

Transl Oncol
Yu L, Zhang H, Jia L, Lai D, Jia L, Li Q, Guo E, Yang F, Zhang B, Luo Q.   +9 more
europepmc   +1 more source

Time- and cell-specific activation of BMP signaling restrains chondrocyte hypertrophy. [PDF]

iScience
Gadomski SJ, Mui BWH, Gorodetsky R, Paravastu SS, Featherall J, Li L, Haffey A, Kim JC, Kuznetsov SA, Futrega K, Lazmi-Hailu A, Merling RK, NIDCD/NIDCR Genomics and Computational Biology Core,, Martin D, McCaskie AW, Robey PG.   +15 more
europepmc   +1 more source

BMP Signaling Is a Prognostic Marker in Patients With Colorectal Cancer and Associates With Frailty. [PDF]

Cancer Diagn Progn
Sawata S, Shimizu S, Matsumi Y, Kono Y, Kihara K, Yamamoto M, Sakamoto T, Umekita Y, Fujiwara Y.   +8 more
europepmc   +1 more source

Ear pinna growth and differentiation is conserved in murids and requires BMP signaling for chondrocyte proliferation.

Development
Allen RS, Biswas SK, Seifert AW.
europepmc   +1 more source