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A genome-engineered tool set for Drosophila TGF-β/BMP signaling studies.
DevelopmentEll CM +6 more
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A whole-body atlas of non-graded BMP signaling activity in a sea anemone
Knabl P, Mörsdorf D, Genikhovich G.
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BMP Signaling and Skeletogenesis
Annals of the New York Academy of Sciences, 2006Abstract: Bone morphogenetic proteins (BMPs) are members of the transforming growth factor (TGF)‐β superfamily of signal molecules that mediate many diverse biological processes ranging from early embryonic tissue patterning to postnatal tissue homeostasis. BMPs trigger cell responses mainly through the canonical signaling pathway where intracellular
Xuelin, Li, Xu, Cao
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BMP signaling in vascular biology and dysfunction [PDF]
Cytokine and Growth Factor Reviews, 2016 The vascular system is critical for developmental growth, tissue homeostasis and repair but also for tumor development. Bone morphogenetic protein (BMP) signaling has recently emerged as a fundamental pathway of the endothelium by regulating cardiovascular and lymphatic development and by being causative for several vascular dysfunctions.
An Zwijsen, Sabine Bailly, Petra Knaus
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The role of SMADS in BMP signaling
Frontiers in Bioscience, 2003Bone morphogenetic proteins, BMPs, are members of the transforming growth factor-beta (TGF-beta) superfamily, which are implicated in embryogenesis, organogenesis, skeletogenesis, osteogenesis, cellular differentiation and apoptosis by regulating the expression of specific target genes.
Riko, Nishimura +6 more
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Science's STKE, 2002
Cytokines of the transforming growth factor-β (TGF-β) superfamily transduce their signals by activating receptor-regulated Smads (R-Smads). Distinct R-Smads or combinations of R-Smads are activated by TGF-β, activin, or bone morphogenetic proteins (BMPs).
Kohei, Miyazono, Keiji, Miyazawa
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Cytokines of the transforming growth factor-β (TGF-β) superfamily transduce their signals by activating receptor-regulated Smads (R-Smads). Distinct R-Smads or combinations of R-Smads are activated by TGF-β, activin, or bone morphogenetic proteins (BMPs).
Kohei, Miyazono, Keiji, Miyazawa
openaire +2 more sources
BMP signaling in skeletal development
Biochemical and Biophysical Research Communications, 2005Development of the vertebrate skeleton, a complex biological event that includes diverse processes such as formation of mesenchymal condensations at the sites of future skeletal elements, osteoblast and chondrocyte differentiation, and three dimensional patterning, is regulated by many growth factors.
Mei, Wan, Xu, Cao
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BMP signaling in vascular development and disease
Cytokine and Growth Factor Reviews, 2010 Genetic and functional studies indicate that common components of the bone morphogenetic protein (BMP) signaling pathway play critical roles in regulating vascular development in the embryo and in promoting vascular homeostasis and disease in the adult ...
Jonathan W Lowery
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