Results 111 to 120 of about 30,982 (215)

Influence of a Heterologous (ChAdOx1-nCoV-19/BNT162b2) or Homologous (BNT162b2/BNT162b2) Vaccination Regimen on the Antibody and T Cell Response to a Third Vaccination with BNT162b2

Emerging numbers of SARS-CoV-2 infections are currently combated with a third vaccination. Considering the different vaccination regimens used for the first two vaccine doses, we addressed whether the previous vaccination influences the immune response ...
Geßner, Reinhard, Mutters, Reinier, Von Blanckenburg, Pia, Thiemer, Julia, Reiter, Rieke, Seifart, Ulf   +5 more
core   +1 more source

Humoral and cellular responses to SARS‐CoV‐2 variants after ancestral COVID‐19 vaccines in people with HIV and lung transplant recipients

Clinical &Translational Immunology, Volume 15, Issue 8, 2026.
This study compares the humoral and cellular immunogenicity of Dose 3 of Ancestral SARS‐CoV‐2 vaccine in participants with HIV and/or following lung transplantation with healthy controls. We highlight differences along a spectrum of immunocompromise, and the value of SARS‐CoV‐2 vaccination, even in the absence of detectable neutralisation responses ...
David WJ Griffin, Paul A Gill, Irene Boo, Shir Sun, Raffi Gugasyan, Alina Wang, Scott J Bornheimer, Stuart Turville, Anupriya Aggarwal, Greg I Snell, Glen P Westall, Emily SJ Edwards, Anna Coldham, Menno C van Zelm, Heidi E Drummer, James H McMahon   +15 more
wiley   +1 more source

Differences in B-Cell Immunophenotypes and Neutralizing Antibodies Against SARS-CoV-2 After Administration of BNT162b2 (Pfizer-BioNTech) Vaccine in Individuals with and without Prior COVID-19 - A Prospective Cohort Study

Journal of Inflammation Research, 2022
José Javier Morales-Núñez,1 Mariel García-Chagollán,1 José Francisco Muñoz-Valle,1 Saúl Alberto Díaz-Pérez,1 Paola Carolina Torres-Hernández,2 Saraí Citlalic Rodríguez-Reyes,3 Guillermo Santoscoy-Ascencio,4 José Julio Sierra García de Quevedo,4 Jorge ...
Morales-Núñez JJ, García-Chagollán M, Muñoz-Valle JF, Díaz-Pérez SA, Torres-Hernández PC, Rodríguez-Reyes SC, Santoscoy-Ascencio G, Sierra García de Quevedo JJ, Hernández-Bello J   +8 more
doaj  

Impact of timing and combination of different BNT162b2 and ChAdOx1-S COVID-19 basic and booster vaccinations on humoral immunogenicity and reactogenicity in adults

Scientific Reports, 2023
In this single-center observational study with 1,206 participants, we prospectively evaluated SARS-CoV-2-antibodies (anti-S RBD) and vaccine-related adverse drug reactions (ADR) after basic and booster immunization with BNT162b2- and ChAdOx1-S-vaccines ...
Simon Dedroogh, Sven Schmiedl, Petra A. Thürmann, Katharina Graf, Sebastian Appelbaum, Reinhard Koß, Christian Theis, Zewarudin Zia, Jürgen Tebbenjohanns, Serge C. Thal, Michael Dedroogh   +10 more
doaj   +1 more source

Heterologous ChAdOx1 nCoV-19/BNT162b2 Prime-Boost Vaccination Induces Strong Humoral Responses among Health Care Workers

, 2021
Despite limited data on safety and immunogenicity, heterologous prime-boost vaccination is currently recommended for individuals with ChAdOx1 nCoV-19 prime immunization in certain age groups.
Florian Kälble, Christian Morath, Mirabel Buylaert, Julia Grenz, Paul Schnitzler, Maximilian Töllner, Christian Nusshag, Gerald Ponath, Caner Süsal, Katrin Klein, Martin Zeier, Claudius Speer, Louise Benning, Matthias Schaier, Asa Hidmark, Paula Reichel   +15 more
core   +1 more source

Immunogenicity and reactogenicity against the SARS-CoV-2 variants following heterologous primary series involving CoronaVac, ChAdox1 nCov-19 and BNT162b2 plus BNT162b2 booster vaccination: An open-label randomized study in healthy Thai adults

, 2022
We evaluated the immunogenicity and reactogenicity of heterologous COVID-19 primary schedules involving BNT162b2 (Pfizer-BioNTech), ChAdOx1 nCoV-19 (AstraZeneca) and CoronaVac (Sinovac) in healthy adults, as well as booster response to BNT162b2 following
Jantraphakorn, Y, Jansarikit, L, Niyomnaitham, S, Mingngamsup, N, Wongprompitak, P, Licciardi, PV, Srisutthisamphan, K, Sapsutthipas, S, Chokephaibulkit, K, Quan Toh, Z   +9 more
core   +2 more sources

Temporal Association Between COVID‐19 Vaccination and HBsAg Loss in Chronic Hepatitis B Infection: An Interrupted Time Series Analysis

Alimentary Pharmacology &Therapeutics, Volume 64, Issue 4, Page 517-526, August 2026.
In 59,946 chronic hepatitis B patients followed over 23 years, COVID‐19 vaccination rollout was temporally associated with a 56% increase in HBsAg loss rates (peak 1.27 per 100 person‐years in 2022), followed by gradual waning. Negative control outcomes showed no similar pattern, supporting biological specificity. ABSTRACT Background and Aims Hepatitis
Jonggi Choi, Allison Carroll, Vy H. Nguyen, Megan Michta, Xuan Q. Zhang, Young‐Suk Lim, Raymond T. Chung   +6 more
wiley   +1 more source

Mechanisms of innate and adaptive immunity to the Pfizer-BioNTech BNT162b2 vaccine

, 2022
Despite the success of the BNT162b2 mRNA vaccine, the immunological mechanisms that underlie its efficacy are poorly understood. Here we analyzed the innate and adaptive responses to BNT162b2 in mice, and show that immunization stimulated potent antibody
Scott, Madeleine K. D., Wang, Yanli, Arunachalam, Prabhu S., Wimmers, Florian, Khatri, Purvesh, Scott, Madeleine K.D., Lee, Audrey, Feng, Yupeng, Kim, Peter, Sanyal, Mrinmoy, Luo, Wei, Valore, Erika, Nadeau, Kari C., Verma, Rohit, Weidenbacher, Payton A., Grigoryan, Lilit, Adamska, Julia Z., O’Hara, Ruth, Dunham, Diane, Pulendran, Bali, Park, Helen, Reis, Noah, Li, Chunfeng, Gitlin, Alexander D., Trisal, Meera   +24 more
core   +1 more source

CoronaVac or BNT162b2 Vaccine as a Third Dose

American Journal of Respiratory and Critical Care Medicine, 2022
Rujittika Mungmunpuntipantip, Viroj Wiwanitkit   +1 more
openaire   +2 more sources

The Role of CD4 T Cell Repertoire and Immune Memory Mechanisms in Vaccination and Infection Immunity

Immunological Reviews, Volume 341, Issue 1, August 2026.
ABSTRACT CD4+ T cells orchestrate adaptive immunity against respiratory viruses through functionally distinct subsets, yet the qualitative differences between vaccine‐ and infection‐induced responses remain incompletely understood. This review summarizes current evidence on how CD4+ T cell subsets shape the magnitude, breadth, and durability of ...
Masato Kubo
wiley   +1 more source