Systematic review and meta-analysis of COVID-19 mRNA vaccine effectiveness against hospitalizations in adults:mRNA vaccine efficacy against COVID-19 hospitalisation [PDF]
BACKGROUND: During the coronavirus disease 2019 (COVID-19) pandemic, Pfizer/BioNTech BNT162b2, and Moderna mRNA-1273 vaccines were central to the global pandemic control measures.METHODS: Here, we conducted a systematic review and meta-analysis to ...
Mabbott, Neil, Wong, Bill
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Hybrid immunity of the SARS-CoV-2 vaccine after the third doses in health workers
Introduction: Hybrid immunity is the immune response of people infected with COVID-19 who received the SARS-CoV-2 vaccine. This combination is more powerful than the immunity that is generated after vaccination or infection alone.
Raúl Montalvo +5 more
doaj
Background/Objectives: This study evaluated the Omicron LP.8.1 variant-adapted BNT162b2 mRNA vaccine (LP.8.1-adapted BNT162b2). Methods: This analysis is part of an ongoing phase 3 open-label study evaluating the immunogenicity, safety, and tolerability ...
Rucha Dadhe +17 more
doaj +1 more source
COVID-19 Immunity in the Cohort of IRCCS San Raffaele Hospital Employees after BNT162b2 Vaccination: A Retrospective Observational Study [PDF]
INTRODUCTION: The COVID-19 pandemic represents the most severe health and socioeconomic crisis of our century. It began with the first reports in China, in the Wuhan region in December 2019, and quickly spread worldwide, causing a new Severe Acute ...
De Lorenzo, Rebecca +8 more
core
Avidity Maturation of Humoral Response Following Primary and Booster Doses of BNT162b2 mRNA Vaccine Among Nursing Home Residents and Healthcare Workers [PDF]
Infections, despite vaccination, can be clinically consequential for frail nursing home residents (NHR). Poor vaccine-induced antibody quality may add risk for such subsequent infections and more severe disease. We assessed antibody binding avidity, as a
Bosch, Jürgen +6 more
core +2 more sources
This 22-month cohort study investigated the durability and dynamics of humoral immune responses in 327 Malaysians vaccinated with either CoronaVac or BNT162b2 in early 2021, monitored up to 52 weeks following a BNT162b2 booster. Using the ImmuSAFE™ COVID
Aini Syahida Mat Yassim +11 more
doaj +1 more source
The SARS-CoV-2 Omicron variant and its sublineages continue to cause COVID-19-associated pediatric hospitalizations, severe disease, and death globally. BNT162b2 and CoronaVac are the main vaccines used in Chile.
Diego A. Díaz-Dinamarca +15 more
doaj +1 more source
Neurovascular Adverse Effects of Sars-Cov-2 Vaccination
Leonidas D Panos,1,2 Panagiotis Bargiotas,2 Georgios Hadjigeorgiou,2 Georgios D Panos3,4 1Department of Neurology, Bern University Hospital « Inselspital », Bern, Switzerland; 2Department of Neurology, School of Medicine, University of Cyprus, Nicosia ...
Panos LD +3 more
doaj
Objectives To compare antispike IgG levels over a period of 182 days of follow-up in healthy adults who received full or fractional booster doses of BNT162b2 or AZD1222 after completing a primary series of Sinovac, BNT162b2 or AZD1222.Design Double-blind,
Haley Hedlin +16 more
doaj +1 more source
Specific and off-target immune responses following COVID-19 vaccination with ChAdOx1-S and BNT162b2 vaccines-an exploratory sub-study of the BRACE trial [PDF]
Background: The COVID-19 pandemic led to the rapid development and deployment of several highly effective vaccines against SARS-CoV-2. Recent studies suggest that these vaccines may also have off-target effects on the immune system.
Arnaiz de las Revillas Almajano, Francisco +19 more
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