Results 91 to 100 of about 29,631 (205)

Association between obstructive sleep apnea (OSA) and COVID‐19 severity

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Obstructive sleep apnea and sleep‐related hypoxia have been associated with higher rates of hospitalization and mortality among patients with Coronavirus disease 2019 (COVID‐19). We further explored the association between obstructive sleep apnea, COVID‐19 severity and related mortality.
Oria Nassi‐Liberman, Bernice Oberman, Tamar Strahl, Noga Yosef, Dekel Shlomi   +4 more
wiley   +1 more source

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu, Yin Dou, Chenwen Li, Yuying Mu, Huiying Ouyang, Wenhao Shen, Jianxiang Zhang   +6 more
wiley   +1 more source

Trajectory of IgG to SARS-CoV-2 After Vaccination With BNT162b2 or mRNA-1273 in an Employee Cohort and Comparison With Natural Infection

Frontiers in Immunology, 2022
Three COVID-19 vaccines have received FDA-authorization and are in use in the United States, but there is limited head-to-head data on the durability of the immune response elicited by these vaccines.
Behnam Keshavarz, Nathan E. Richards, Lisa J. Workman, Jaimin Patel, Lyndsey M. Muehling, Glenda Canderan, Deborah D. Murphy, Savannah G. Brovero, Samuel M. Ailsworth, Will H. Eschenbacher, Emily C. McGowan, Barbara J. Mann, Michael R. Nelson, Alexandra Kadl, Alexandra Kadl, Judith A. Woodfolk, Thomas A.E. Platts-Mills, Jeffrey M. Wilson   +17 more
doaj   +1 more source

Efficacy and Safety of Messenger RNA Vaccines

Health Science Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background and Aims The rapid development of mRNA vaccines has revolutionized infectious disease prevention and cancer immunotherapy. While their efficacy is well established, concerns about safety and immunopathological risks persist. This study aims to evaluate the immunogenicity, safety profiles, and design considerations of mRNA vaccines ...
Kesaobaka Batisani, David Chisompola
wiley   +1 more source

BNT162b2-induced antibody levels 2 weeks, 3 and 8 months after first vaccination.

, 2022
(A) Reciprocal titers of SARS-CoV-2 neutralizing antibodies were measured in focus reduction neutralization assay with inhibitor titer 90% (FRNT90).
Stephan Borte (311575), Christoph Lübbert (3172290), Nils Kellner (7010144), Johannes Wolf (564853), Sven Kalbitz (10198514), Alexandra Rockstroh (826149), Susann Landgraf (13977678), Corinna Pietsch (10011954), Jasmin Fertey (842054), Michael Borte (250182), Olaf Nickel (9524791), Sebastian Ulbert (420908)   +11 more
core   +1 more source

Immunogenicity and reactogenicity of SARS-CoV-2 vaccines BNT162b2 and CoronaVac in healthy adolescents

, 2022
We present an interim analysis of a registered clinical study (NCT04800133) to establish immunobridging with various antibody and cellular immunity markers and to compare the immunogenicity and reactogenicity of 2-dose BNT162b2 and CoronaVac in healthy ...
Cheng, Samuel M. S., Valkenburg, S, Chan, Karl C.K., Wong, WHS, Ip, P, Hung, TK, Tsang, Leo C. H., Luk, LLH, Tsang, LCH, Kwan, Kelvin K.H., Chan, KCK, Peiris, M, Lam, Jennifer H. Y., Hachim, A, Tu, Wenwei, Cheng, SMS, Chua, Gilbert T., Cohen, Carolyn A., Leung, Wing Hang, Tsang, Leo C.H., Leung, WH, Kavian, N, Mori, Masashi, Cheang, Cheuk Hei, Li, JKC, Mu, Xiaofeng, Chua, GT, Hung, Timothy K., Cheang, CH, Kwan, Kelvin K. H., Li, John K.C., Leung, Daniel, Lam, Jennifer H.Y., Rosa Duque, JS, Chan, Karl C. K., Luk, Leo L.H., Zhang, Yanmei, Ip, Patrick, Cohen, CA, Rosa Duque, Jaime S., Chan, SM, Tso, Winnie W.Y., Wang, X, Tso, WWY, Mori, M, Wong, Wilfred H.S., Valkenburg, Sophie, Chaothai, S, Lau, YL, Tso, Winnie W. Y., Peiris, Malik, Lau, Yu Lung, Leung, D, Kavian, Niloufar, Zhang, Y, Mu, X, Li, John K. C., Chaothai, Sara, Luk, Leo L. H., Wang, Xiwei, Tu, W, Cheng, Samuel M.S., Chan, Sau Man, Wong, Wilfred H. S., Hachim, Asmaa, Kwan, KKH, Lam, JHY   +66 more
core   +1 more source

Boosting BNT162b2 vaccine efficacy in CLL [PDF]

Blood, 2022
Bhat, Seema A., Woyach, Jennifer A.
openaire   +2 more sources

The Association Between MOG‐IgG Positivity and mRNA SARS‐CoV‐2 Vaccination in Denmark: A Self‐Controlled Case Series Study

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 6, June 2026.
ABSTRACT Purpose Spontaneous reporting of a possible link between myelin oligodendrocyte glycoprotein (MOG) antibody‐associated disease (MOGAD) and mRNA SARS‐CoV‐2 vaccination warrants further examination. Hence, the objective of this study was to investigate the association between MOG‐IgG positivity as a proxy for MOGAD and mRNA SARS‐CoV‐2 ...
Tine Iskov Kopp, Anne Katrine Andreasen, Viktoria Papp, Mette Hjorslev Knudgaard, Heidi Jeannet Graff, Michelle S. Clement, Nicklas Hasselblad Lundstrøm, Stine Ulsø, Mona El‐Sayed Hervig, Charlotte Wessel Skovlund   +9 more
wiley   +1 more source

Humoral and cellular immune response over 9 months of mRNA-1273, BNT162b2 and ChAdOx1 vaccination in a University Hospital in Spain

Scientific Reports, 2022
Scarce data have been reported about cellular immunity and longevity for different COVID-19 vaccination schedules. We carried out a prospective study enrolling 709 healthcare workers receiving two doses of mRNA-1273, BNT162b2, ChAdOx1, ChAdOx1/BNT162b2 ...
Leire Fernández-Ciriza, Álvaro González, José Luis del Pozo, Alejandro Fernández-Montero, Francisco Carmona-Torre, Silvia Carlos, María del Mar Sarasa, Gabriel Reina   +7 more
doaj   +1 more source

Immunosenescence and Vaccine Efficacy in Aging: Dynamic Interplay of Gut Microbiota and mTOR Signaling Pathways

Aging Cell, Volume 25, Issue 6, June 2026.
Aging impairs vaccine efficacy through gut microbiota dysbiosis and mTOR hyperactivation, which together drive inflammaging and weaken immune memory. This review highlights the bidirectional microbiota–mTOR axis and proposes that combining mTOR inhibitors with microbiota modulation offers a promising strategy to enhance vaccine responses in older ...
Jiaxuan Li, Yuhong Zhang, Daijun Yu, Jianhua Li, Keda Chen, Lisheng Chu   +5 more
wiley   +1 more source