Results 171 to 180 of about 26,921 (258)

Compromised DNA replication in gut cells underlies sensitivity to genotoxic stress in the tardigrade Hypsibius exemplaris

The FEBS Journal, EarlyView.
DNA damage in the tardigrade Hypsibius exemplaris elicits distinct cellular outcomes depending on replication status. While non‐replicating cells tolerate genotoxic stress, constitutively replicating cells undergo irreversible replication failure upon DNA damage, leading to loss of tissue homeostasis, fat depletion, sterility, and organismal death ...
Gonzalo Quiroga‐Artigas, Pauline Fontanié, Benjamin Lacroix, Maria Dolores Molina, María Moriel‐Carretero   +4 more
wiley   +1 more source

Phosphatidylethanolamine Alleviates Osteoarthritis Progression by Inhibiting Oxidative Stress-Induced Chondrocyte Ferroptosis in a Lysosomal-Dependent Manner. [PDF]

Int J Gen Med
Zheng H, Zhu Z, Zhu J, Chen D, Ruan R, Ning R.   +5 more
europepmc   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

The FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney, James Griffin, Nouf Khan, Balnur Ibrash, Matthew J. O'Connor, Tomas Venit, Elizabeth Mayela Ambrosio, Spiros A. Pergantis, Elke Ober, Piergiorgio Percipalle, Kirsten C. Sadler   +10 more
wiley   +1 more source

Questing for Integrin Targeting Theranostics for Cancer Cell-Selective Molecules. [PDF]

ACS Omega
Giraldi V, Pecoraro T, Maurizio A, Milana A, De Cola L, Baiula M, Giacomini D.   +6 more
europepmc   +1 more source

Antimicrobial photodynamic therapy in Candida spp. biofilms: In vitro and in vivo protocols

Photochemistry and Photobiology, EarlyView.
This review addresses the critical challenges in translating in vitro antimicrobial photodynamic therapy protocols to in vivo models, with a particular focus on the hurdles of standardization. The vast diversity in photosensitizers and light parameters across different target cells and models requires a rigorous optimization process.
Lívia Mara Alves Figueiredo‐Godoi, Ana Júlia Barbosa Tomé, Cristina Kurachi   +2 more
wiley   +1 more source

Superacid-resistant macrocyclic BODIPYs. [PDF]

Nat Commun
Watanabe K, Honda G, Terauchi Y, Mamiya S, Inaba Y, Nakajima T, Gong JP, Yamaguchi Y, Kitagawa Y, Hasegawa Y, Ide Y, Gao M, Yoneda T, Inokuma Y.   +13 more
europepmc   +1 more source

A primary cell‐based fluidic co‐culture model to investigate drug transport across the human placenta

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of a flow‐driven in vitro model of the human placental barrier designed to study transport processes during pregnancy. The model recreates key features of the maternal–fetal interface, enabling the investigation of how nutrients and therapeutic compounds cross the placental barrier under physiologically ...
Barbara Fuenzalida, Nadja Koechli, Edgar Ontsouka, Chennakesava Cuddapah, Martin Mueller, Bram Sengers, Frantisek Staud, Christiane Albrecht   +7 more
wiley   +1 more source

Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution. [PDF]

Angew Chem Int Ed Engl
Raabe K, Kalaba P, Yong XLH, Crudeli G, Melzer S, Keimpema E, Anggono V, Muttenthaler M.   +7 more
europepmc   +1 more source

Positive Encapsulation‐Induced Emission Control of Aggregation‐Induced Emission‐Active Anthracenes within Micellar Capsules in Water

Aggregate, Volume 7, Issue 7, July 2026.
Aggregation‐induced emission (AIE)‐active dialkylamine‐substituted anthracenes show strong green emission upon encapsulation by micellar capsules in 100% water. The encapsulation‐induced AIE effect depends on the substitution pattern of the anthracene framework.
Ryuki Kitaura, Yuta Kikuchi, Lorenzo Catti, Kensei Konishi, Gen‐ichi Konishi, Michito Yoshizawa   +5 more
wiley   +1 more source

Highly Selective Fluorescence Sensing of Ba2+ With a Benzo‐21‐Crown‐7‐Based BODIPY Through Modulation of an Intramolecular Charge Transfer in Aqueous Solution

Analysis &Sensing, Volume 6, Issue 4, July 2026.
A benzo‐21‐crown‐7 BODIPY dye (fluorescent probe) serves as a highly selective fluorescent probe for Ba2+ in aqueous solution. Ba2+ binding triggers a strong fluorescence enhancement, enabling sensitive detection with high selectivity, pH stability, and robustness under prolonged illumination.
Thomas Schwarze, Mazen Al Akrami, Tobias Sprenger, Nora Kulak   +3 more
wiley   +1 more source