Results 181 to 190 of about 27,097 (262)

Questing for Integrin Targeting Theranostics for Cancer Cell-Selective Molecules. [PDF]

ACS Omega
Giraldi V, Pecoraro T, Maurizio A, Milana A, De Cola L, Baiula M, Giacomini D.   +6 more
europepmc   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

The FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney, James Griffin, Nouf Khan, Balnur Ibrash, Matthew J. O'Connor, Tomas Venit, Elizabeth Mayela Ambrosio, Spiros A. Pergantis, Elke Ober, Piergiorgio Percipalle, Kirsten C. Sadler   +10 more
wiley   +1 more source

Photocaged Oxytocin and Vasopressin Probes to Decipher Neuropeptide Signalling With High Spatiotemporal Resolution. [PDF]

Angew Chem Int Ed Engl
Raabe K, Kalaba P, Yong XLH, Crudeli G, Melzer S, Keimpema E, Anggono V, Muttenthaler M.   +7 more
europepmc   +1 more source

Single‐Cell Transcriptomics Reveals the FA9–VAP Module Regulating Fatty Acid Accumulation in Soybean Seeds

Plant Biotechnology Journal, EarlyView.
ABSTRACT As a major commercial legume crop, soybean ranks among the world's most significant sources of edible oil and plant protein. We previously identified a SEIPIN homologue (FA9) at the fatty acid 9 locus that promotes fatty acid accumulation in soybean.
Hui Li, Tianshu Li, Xiaorui Xu, Jinhang Cui, Xin Chen, Jingyi Huang, Jia Song, Cui Mu, Xinyu Hong, Chunyan Liu, Ning Wang, Xue Han, Sui Wang, Qingshan Chen, Zhaoming Qi   +14 more
wiley   +1 more source

Superacid-resistant macrocyclic BODIPYs. [PDF]

Nat Commun
Watanabe K, Honda G, Terauchi Y, Mamiya S, Inaba Y, Nakajima T, Gong JP, Yamaguchi Y, Kitagawa Y, Hasegawa Y, Ide Y, Gao M, Yoneda T, Inokuma Y.   +13 more
europepmc   +1 more source

Antimicrobial photodynamic therapy in Candida spp. biofilms: In vitro and in vivo protocols

Photochemistry and Photobiology, EarlyView.
This review addresses the critical challenges in translating in vitro antimicrobial photodynamic therapy protocols to in vivo models, with a particular focus on the hurdles of standardization. The vast diversity in photosensitizers and light parameters across different target cells and models requires a rigorous optimization process.
Lívia Mara Alves Figueiredo‐Godoi, Ana Júlia Barbosa Tomé, Cristina Kurachi   +2 more
wiley   +1 more source

Characterization of Proline-Rich Antimicrobial Peptides with SbmA Transporter-Dependent and Independent Antimicrobial Activity toward <i>Klebsiella pneumoniae</i>. [PDF]

ACS Infect Dis
Appiah RM, Beckman RL, DeBarro CM, Ren H, Brodbelt JS, Fleeman RM.   +5 more
europepmc   +1 more source

A primary cell‐based fluidic co‐culture model to investigate drug transport across the human placenta

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of a flow‐driven in vitro model of the human placental barrier designed to study transport processes during pregnancy. The model recreates key features of the maternal–fetal interface, enabling the investigation of how nutrients and therapeutic compounds cross the placental barrier under physiologically ...
Barbara Fuenzalida, Nadja Koechli, Edgar Ontsouka, Chennakesava Cuddapah, Martin Mueller, Bram Sengers, Frantisek Staud, Christiane Albrecht   +7 more
wiley   +1 more source

Macrophage lipid efflux regulates the tumour microenvironment in early‐stage lung adenocarcinoma

Clinical and Translational Discovery, Volume 6, Issue 5, October 2026.
1. Macrophages undergo metabolic rewiring even during early tumourigenesis. 2. Main alterations of macrophages are conserved between human and mice in early‐stage lung adenocarcinoma. 3. Tumour‐associated macrophages are characterised by enhanced lipid efflux 4.
Yujie Zheng, Yuan Wang, Yalin Wang, Yue Shi, Hui Kong, Shaohua Lu, Yong Zhang, Jie Hu, Jian Zhou, Xiangdong Wang, Meng Xiang, Qiong Liu, Hongyi Xin, Charles A. Powell, Fred R. Hirsch, Chunxue Bai, Yuanlin Song, Jun Yin, Dawei Yang   +18 more
wiley   +1 more source

Macrocyclic Peptides Containing an Imidazopyridinium (IP⁺) Unit Display Enhanced Passive Cell Permeability. [PDF]

J Am Chem Soc
Li B, Parker J, Briggs S, Dong J, Wang C, Fu CW, Burke JM, Kodadek T.   +7 more
europepmc   +1 more source