Results 181 to 190 of about 26,921 (258)

USP43‐mediated deubiquitination of SLC7A11 protects against LPS‐induced acute lung injury by inhibiting ferroptosis

open access: yesClinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Ubiquitin‐specific protease 43 (USP43) in up‐regulated during lipopolysaccharide (LPS)‐induced acute lung injury (ALI). USP43 interacts and inhibits the degradation of solute carrier family 7 member 11 (SLC7A11) by removing the K48‐linked ubiquitination of it, thereby suppressing ferroptosis.
Li Zhang   +7 more
wiley   +1 more source

A Microscale Platform for the Comprehensive Analysis of Bacterial Translation Initiation. [PDF]

open access: yesInt J Mol Sci
Vinogradova DS   +10 more
europepmc   +1 more source

CRISPR‐Based Gene Dependency Screens Reveal Mechanism of BRAF Inhibitor Resistance in Anaplastic Thyroid Cancer

open access: yesMolecular Carcinogenesis, Volume 65, Issue 7, Page 874-887, July 2026.
ABSTRACT Anaplastic thyroid cancer (ATC) is the most aggressive form of thyroid cancer. Despite recent advances in treating BRAFV600E‐driven ATC, therapy resistance remains a significant challenge, often resulting in disease progression and death.
Shawn Noronha   +26 more
wiley   +1 more source

Amyloid‐β aggregates induce vasculopathy via ferroptosis in brain endothelial cells

open access: yesBrain Pathology, Volume 36, Issue 4, July 2026.
Blood–brain barrier (BBB) disruption is evident in brains with amyloidopathy. In this study, we demonstrate that amyloid β (Aβ) drives abnormal lipid metabolism and lipid droplet formation in brain endothelial cells, leading to lipid peroxidation and ferroptosis.
Suhyeon Son   +7 more
wiley   +1 more source

SIRT1 Prevents Ferroptosis in Corneal Epithelial Cells by Enhancing HIF1α Protein Stability in Dry Eye Disease. [PDF]

open access: yesAdv Sci (Weinh)
Lian L   +11 more
europepmc   +1 more source

From EM to AI: Multiscale imaging of the secretory pathway with insights from plant cells

open access: yesJournal of Microscopy, Volume 303, Issue 1, Page 3-20, July 2026.
Abstract The secretory pathway is a central and evolutionarily conserved feature of eukaryotic cells, responsible for protein and lipid trafficking, membrane biogenesis, signalling, and cellular homeostasis. Its complexity, dynamic behaviour, and nanoscale organisation have made it a longstanding target of microscopy‐driven investigation.
Charlotte Pain, Emily Farley
wiley   +1 more source

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