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The Borna disease virus (BoDV) 2 nucleoprotein is a conspecific protein that enhances BoDV-1 RNA-dependent RNA polymerase activity

The Borna disease virus (BoDV) 2 nucleoprotein is a conspecific protein that enhances BoDV-1 RNA-dependent RNA polymerase activity
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Cerebrospinal fluid in Borna disease virus 1 (BoDV-1) encephalitis

Journal of the Neurological Sciences, 2023
Borna disease virus 1 (BoDV-1) has been recognized as a rare cause of very severe encephalitis with rapid onset in central Europe. Data on cerebrospinal fluid (CSF) analysis have not yet been analyzed in detail. Here, we present the first study on CSF changes in BoDV-1 encephalitis.
Bernhard, Neumann, Andreas, Hierl, Silke, Wunderlich, Helen, Meier, Christina, Bauer, Stefan T, Gerner, Georg, Rieder, Tobias, Geis, Jürgen, Kunkel, Markus, Bauswein, Hans Helmut, Niller, Barbara, Schmidt, Dennis, Rubbenstroth, Martin, Beer, Ralf A, Linker, Jonathan, Jantsch, Klemens, Angstwurm   +16 more
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Nucleoprotein (P40) Binding to 5HT2C Receptors (5HT2CR) is the Key Point in the Pathogenesis of BoDV-1-Infected Hosts

Neurochemical Research, 2021
Nucleoprotein (P40) is one of the most important proteins of Borna disease virus 1 (BoDV-1), but which proteins it would bind to in the pathogenesis of BoDV-1-infected hosts is unknown. We used lentivirus LV5-P40 overexpressing P40 to infect primary hippocampal neurons and characterized the interactome of P40 with co-immunoprecipitation (Co-IP ...
Yuanxin Li, Lixin Wang, Xueni Liu, Ying Huang, Xiaomei Li, Hong He, Xiaoyan Xu, Yujie Guo, Qi Li, Dan Zhu, Xingyu Wang, Haiyang Wang, Wenwen Li, Dan Li, Peng Xie   +14 more
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BoDV‐1 infection induces neuroinflammation by activating the TLR4/MyD88/IRF5 signaling pathway, leading to learning and memory impairment in rats

Journal of Medical Virology, 2021
AbstractBorna disease virus (BoDV‐1) can infect the hippocampus and limbic lobes of newborn rodents, causing cognitive deficits and abnormal behavior. Studies have found that neuroinflammation caused by viral infection in early life can affect brain development and impair learning and memory function, revealing the important role of neuroinflammation ...
Tian Tang, Yujie Guo, Xiaoyan Xu, Libo Zhao, Xia Shen, Lin Sun, Peng Xie   +6 more
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Bornavirus (BoDV-1) Encephalitis in Children: Update on Diagnosis and Treatment

Neuropediatrics
AbstractInfectious encephalitis in children can be caused by several pathogens, very rarely this can be caused by bornaviruses (BoDV-1). Due to the recent discovery of the disease in humans and the small number of cases, especially pediatric infections, knowledge about the disease pathology as well as therapeutic options is limited.
Victoria Lieftüchter, Yannik Vollmuth, Moritz Tacke, Florian Hoffmann, Marco Paolini, Tom Finck, Friederike Liesche-Starnecker, Ulrich von Both, Kirsten Pörtner, Dennis Tappe, Leonie Grosse   +10 more
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Die Hausspitzmaus als Tierversuchsmodell für Reservoirwirte von BoDV-1

Tierärztliche Praxis Ausgabe K: Kleintiere / Heimtiere, 2021
D Nobach, L Raeder, S Herzog, M Eickmann, C Herden   +4 more
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Borna Disease Virus 1 (BoDV-1): Aktueller Stand und Perspektiven

Krankenhaushygiene up2date, 2023
Markus Bauswein, Benedikt M.J. Lampl, Matthias Pregler, Hans Helmut Niller, Merle M. Böhmer, Barbara Schmidt   +5 more
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Borna Disease (Borna Disease Virus-1, BoDV-1)

2023
Merle M. Böhmer, Markus Bauswein
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Bornavirus-Enzephalitiden (Borna disease virus 1, BoDV-1; variegated squirrel bornavirus 1, VSBV-1)

Zeitschrift für Gastroenterologie, 2023
Dennis Rubbenstroth, Martin Beer
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Enzephalitis durch Borna Disease Virus 1 (BoDV-1): Von Spitzmäusen und Menschen

Trillium Diagnostik, 2023
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