Results 81 to 90 of about 2,597,348 (347)
Alʹmanah Kliničeskoj Mediciny, 2018 Background: Obesity is an important health problem, as its prevalence has reached an epidemic level and continues to increase steadily resulting in higher risk of cardiovascular diseases and metabolic disorders.
I. V. Misnikova +3 more
doaj +1 more source
Deficiency in clonogenic endometrial mesenchymal stem cells in obese women with reproductive failure – a pilot study [PDF]
, 2013 The mechanisms of obesity associated reproductive complications remain poorly understood. Endometrial mesenchymal stem-cells are critical for cyclic renewal and uterine function.
Bhandari, Harish +7 more
core +2 more sources
FEBS Open Bio, EarlyView.Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley +1 more source
Income and body mass index in Europe [PDF]
The problem of obesity is alarming public health authorities around the world. Therefore, it is important to study its determinants. In this paper we explore the empirical relationship between household income and body mass index (BMI) in nine European ...
Climent Quintana-Domeque +1 more
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The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
FEBS Open Bio, EarlyView.We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda +9 more
wiley +1 more source
Instilling Diet and Exercise Confidence: Influence of Nurse Body Size [PDF]
, 2014 This paper reports a research study focused on perspective of nurse body size and how it affects confidence in a nurses’ ability to provide education on diet and exercise.
Spaulding, Erin Murdock
core +4 more sources
Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo
FEBS Open Bio, EarlyView.The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu +12 more
wiley +1 more source
Time Discounting and the Body Mass Index [PDF]
In many Western countries, the relative weight of people – measured by the Body Mass Index (BMI) – has increased substantially in recent years, leading to an increasing incidence of overweight and related health problems.
Borghans,Lex, Golsteyn,Bart H.H.
core +1 more source
High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer
FEBS Open Bio, EarlyView.Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson +5 more
wiley +1 more source
Association between Body Mass Index, Type of Occupation, History of Chronic Illness, and Poor Occupational Posture [PDF]
, 2018 Background: Good posture is important for an individual health as well as appearance. Poor occupational posture may cause negative impacts such as soreness & pain, poor circulation, negative mood, increased stress, carpal tunnel synd¬rome, less ...
Indarto, D. (Dono ) +2 more
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