Results 101 to 110 of about 609,357 (298)
A simple matter of life and death : the trials of postnatal beta-cell mass regulation [PDF]
Pancreatic beta-cells, which secrete the hormone insulin, are the key arbiters of glucose homeostasis. Defective beta-cell numbers and/or function underlie essentially all major forms of diabetes and must be restored if diabetes is to be cured. Thus, the
Elena Tarabra +5 more
core +1 more source
Variations of Endocrine Hormones Concentrations in Tupaia belangeri under Simulated Seasonal Acclimatized: Role of Leptin Sensitivity [PDF]
Seasonal variations in endocrine hormones concentrations are important for the survival of small mammals during acclimatization. In order to understand the role of leptin sensitivity on other endocrine hormones concentrations, we examined body mass ...
Zhu, Wan-long +3 more
doaj
Roles of Ghrelin and Leptin in Body Mass Regulation under Food Restriction Based on the AMPK Pathway in the Red-Backed Vole, Eothenomys miletus, from Kunming and Dali Regions. [PDF]
Liu Y, Jia T, Ren Y, Wang Z, Zhu W.
europepmc +1 more source
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source
Parent-offspring transmission of adipocytokine levels and their associations with metabolic traits [PDF]
Adipose tissue secreted cytokines (adipocytokines) have significant effects on the physiology and pathology of human metabolism relevant to diabetes and cardiovascular disease. We determined the relationship of the pattern of these circulating hormones
Nasser M. Al-Daghri +34 more
core +1 more source
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source
Gonadal and photoperiodic influences on body mass regulation in adult male and female prairie voles
Nontropical animals commonly use the annual change in photoperiod to phase seasonal adjustments that promote survival and reproduction. To cope with the energetic requirements of winter, many rodents alter body mass in anticipation of winter ...
L. J. Kriegsfeld, R. J. Nelson
core +1 more source
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Objective: Thinness can have substantial consequences for child development and health. Adipokines, including leptin and adiponectin, play a significant role in the regulation of important metabolic functions.
Jadwiga Ambroszkiewicz +5 more
doaj +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source

