Results 91 to 100 of about 8,859,342 (293)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

The behaviour of a neutral model of weight regulated only by body mass

open access: yesJournal of Theoretical Biology, 2011
While there are many mechanisms that may be involved in the regulation of body mass in humans and other animals, it is not so clear how much regulation is needed beyond the negative feedback effect of body mass itself. Here we model weight changes as a stochastic process, and show that it behaves approximately as an autoregressive process.
openaire   +4 more sources

The use of body mass index to predict body composition in children

open access: yes, 2002
Background. Simple anthropometric indices of body composition have particular appeal for use in children, and as such body mass index (BMI) has been used to predict percentage body fat in a number of studies. Aim: To evaluate the relationship between BMI
Ball, EJ   +15 more
core   +1 more source

Are Men More Intuitive When It Comes to Eating and Physical Activity?

open access: yesAmerican Journal of Men's Health, 2012
The purpose of this study was to determine where men fall on the motivation continuum based on intuitive eating status and if motivation for physical activity and intuitive eating are correlated.
Julie Gast PhD, MCHES   +2 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

A body composition model to estimate mammalian energy stores and metabolic rates from body mass and body length, with application to polar bears [PDF]

open access: yes, 2009
Many species experience large fluctuations in food availability and depend on energy from fat and protein stores for survival, reproduction and growth. Body condition and, more specifically, energy stores thus constitute key variables in the life history
Molnár, Péter K.   +4 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Variations of Endocrine Hormones Concentrations in Tupaia belangeri under Simulated Seasonal Acclimatized: Role of Leptin Sensitivity [PDF]

open access: yesJournal of Stress Physiology & Biochemistry, 2013
Seasonal variations in endocrine hormones concentrations are important for the survival of small mammals during acclimatization. In order to understand the role of leptin sensitivity on other endocrine hormones concentrations, we examined body mass ...
Zhu, Wan-long   +3 more
doaj  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

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