Results 71 to 80 of about 609,357 (298)
Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture [PDF]
, 2013 Approaches exploiting trait distribution extremes may be used to identify loci associated with common traits, but it is unknown whether these loci are generalizable to the broader population.Liuzzi, A, Harst, P. (Pim) van der, Klauw, M.M. van der, Cookson, WO, Preuss, M., Cusi, D., Ridker, P.M., D. Absher, Assimes, Themistocles L., Heid, I. M., Ingelsson, E., Jianjun Liu, Van Meurs, JBJ, Sanna, Serena, Hall, A.S. (Alistair), Boerwinkle, E., Jean Ferrières, Anneli Pouta, Huffman, J.E. (Jennifer), Qi, L., Hicks, Andrew A, Palmer, L.J., Hengstenberg, Christian, Tregouet, David-Alexandre, van der Klauw, MM (Melanie), Van der Klauw, Melanie M, Peters, Annette, Trip, Mieke D., A. S. Hall, A. U. Jackson, Pedersen, Nancy, Sanders, A. R., Huffman, JE, Smith, AV, Stančáková, A, Ferrario, MM, Dedoussis, G. V., Felix R Day, Liuzzi, A., Antti Jula, Puetter, Carolin, Qi, Lu, Palmer, CN, Monda, Keri L., Uitterlinden, André G, Brenda Penninx, D. Meyre, Frayling, Timothy, Boehm, Bernhard O, O´Connell, J.R., Laitinen, Jaana H, de Vegt, F, S. Kathiresan, Sambrook, Jennifer G., Froguel, P. (Philippe), Stefansson, K, Willemsen, G.A.H.M. (Gonneke), Palmer, Lyle J., Kleber, M. E., Justice, Anne E, M. den Heijer, Jaana H Laitinen, Wichmann, H.E. (Heinz Erich), Waite, L.L., Day, F. R., J. M. Connell, Nicholson, G., Jianxin Shi, Montgomery, G.W., Rose, Lynda M, Harris, T.B. (Tamara), Theodoraki, E.V., Boomsma, D. I., J. Kuusisto, Dedoussis, GV, Milani, L., Sanders, A.R., Munroe, PB, Cupples, L.A. (Adrienne), Å. Johansson, A. R. Wood, Kivimäki, M, Liu, Jianjun, Cusi, D. (Daniele), Qi, L, Rose, L.M. (Lynda), Michael A Province, Radhakrishnan, A. (Aparna), Dimitriou, M, Attwood, AP, Peters, M. J., Rivadeneira, F, S. H. Wild, K. B. Jacobs, Gyllensten, Ulf,, M. Dimitriou, Strachan, David P., Schreiber, S., Hall, AS, Ong, KK, Folkert W Asselbergs, M. J. Caulfield, Johnson, T, B. Penninx, M. Kumari, Penninx, B.W.J.H., V. Steinthorsdottir, Wolffenbuttel, Bruce H., Rudan, I. (Igor), Workalemahu, Tsegaselassie, Lee, Sang Hong, Winkelmann, B.R., Nohr, E. A., Kanoni, S. (Stavroula), Stolk, Ronald P; id_orcid, Sirkka M Keinanen-Kiukaanniemi, Dedoussis, George V., Morris, A. D., Peter S Chines, et al., Julius S Ngwa, D. C. Croteau Chonka, Ouwehand, Willem H, Hirschhorn, J. N., Karl-Heinz Jöckel, Zillikens, M. C., Hyppönen, E. (Elina), W. O. Cookson, Lee, S., Schlessinger, D. (David), Maria Dimitriou, Mariano Dei, Sorensen, TIA, Morris, Andrew, C. M. Lindgren, Vitart, Veronique, Homuth, G. (Georg), J. B. J. van Meurs, Scherag, A. (Andre), Iribarren, Carlos, Johansson, Åsa,, Martin, Nicholas G, Cupples, L.A., Lee, SH, Musk, AW, F. Karpe, C. Langenberg, Morris, AD, Morris, AP, Christian Hengstenberg, Wright, A.F., Shin, SY, Pawitan, Y, Jaakko Tuomilehto, Magnusson, Patrik K., Evelin Mihailov, Hyppönen, Elina, Ong, K.K., R. J. Strawbridge, Wareham, N.J., Pawitan, Y. (Yudi), Ulf Gyllensten, de Faire, Ulf, M. F. Moffatt, Di Blasio, A.M. (Anna Maria), Virtamo, J. (Jarmo), Wild, S.H. (Sarah), William O Cookson, Hunt, Sarah E, Erdmann, Jeanette, Ngwa, JS, I. M. Heid, Hinney, A, B. A. Oostra, Stavroula Kanoni, Stancáková, A. (Alena), Heath, A.C., Marek, D. (Diana), Illig, T., Hall, Per, Uusitupa, M. (Matti), Swift, A.J. (Amy), Van Der Harst, P., Nolte, I.M. (Ilja), Patrik K Magnusson, Barbara McKnight, Visscher, PM, M. Mangino, Monda, K.L., Hicks, Andrew A., Muehleisen, TW, Jackson, A.U., A. Hartikainen, Andrew P Morris, Annette Peters, Wilson, James F, Mühleisen, Thomas W, T. I. A. Sørensen, E. V. Theodoraki, Min, J. L., Peters, Marjolein, Tönjes, A. (Anke), Iris M Heid, Brambilla, Paolo, Liu, J. (Jianjun), Witteman, Jacqueline C.M., Asselbergs, FW, Ripatti, S., S. Pechlivanis, Johan G Eriksson, Pedersen, N.L. (Nancy), Wallaschofski, Henri, E. A. Nohr, de Faire, U., Heard-Costa, Nancy L., Erdmann, J, Kee, Frank, Wright, AF, Hottenga, J.J., Ferrario, Marco M., Farrall, M. (Martin), Wood, Andrew R, Palmer, LJ, Peter M Visscher, März, W. (Winfried), Hicks, A.A., Fall, T, Boehm, B.O., Hirschhorn, J.N. (Joel), Stumvoll, M. (Michael), Polasek, Ozren, Thorsteinsdottir, U, M Carola Zillikens, Keinanen Kiukaanniemi, S. M., Ruth J F Loos, Magnusson, Patrik K, Jarvelin, MR, Snieder, H. (Harold), Justice, A.E., Sørensen, TI, Salomaa, V. (Veikko), van Duijn, Cornelia M., Eriksson, J.G., Thorsteinsdottir, U. (Unnur), Antony P Attwood, Miriam F Moffatt, Elisabeth Widén, Huffman, J. E., Psaty, B. M., Groop, L. (Leif), Winkler, T.W., Francesca Frau, Mueller-Nurasyid, M, Skrobek, B. (Boris), Medland, S.E., Asselbergs, Folkert W, Nohr, Ellen A, Rose, L. M., Wang, Z.M., Stefan Schreiber, Jackson, Anne U, J. E. Huffman, Steinthorsdottir, V. (Valgerdur), Snieder, Harold, Shi, JX, Sanders, Alan R, Medina-Gomez, M.C. (Carolina), Ferreira, T., Barroso, Ines, Oldehinkel, Albertine J, Ferrieres, J., Collins, FS, Moffatt, M. F., George V Dedoussis, Elena Tremoli, Heard-Costa, NL, Zhao, JH, Nolte, IM, Kuusisto, J. (Johanna), Laakso, M. (Markku), Niina Eklund, D. Kuh, D. F. Levinson, R. C. Kaplan, Kivimaki, M., Kaplan, R.C., Jennifer G Sambrook, Pramstaller, PP, Shi, J., Theodoraki, Eirini V, Vollenweider, P, Pouta, A. (Anneli), Ngwa, Julius S, Lee, S.H. (Sang Hong), Stolk, Ronald P, Visscher, Peter M., Kutalik, Z. (Zoltán), Esko, T. (Tõnu), Barroso, I.E. (Inês), North, KE, L. Qi, Wheeler, Eleanor, L. A. Cupples, Swift, A. J., McCarthy, M.I. (Mark), Marjo-Riitta Jarvelin, Spector, Timothy D, Tove Fall, Duijn, C.M. (Cornelia) van, C. Gieger, Trip, MD, van Meurs, Joyce B.J., Psaty, Bruce M., Gejman, P.V. (Pablo), I. Njølstad, Kiemeney, L.A.L.M., Mihailov, Evelin, Attwood, Antony P, Vliet-Ostaptchouk, J.V. Van, Klauw, M.M. (Melanie) van der, Tuomilehto, J., A. R. Sanders, Sarah E Medland, Swift, Amy J, U. Thorsteinsdottir, Signorini, Stefano, Frayling, T, Nicholson, George, Deloukas, P, , M. dei, Vedantam, S. (Sailaja), Ellen A Nohr, Joeckel, Karl-Heinz, Scherag, Andr, Jarick, I. (Ivonne), Launer, L. J., Serena Sanna, J. Tyrer, FERRARIO, MARCO MARIO ANGELO, Heid, I.M. (Iris), R. Mägi, Ngwa, J.S., Chasman, D.I. (Daniel), E. Ingelsson, Mohlke, K.L., Day, Felix R., Campbell, Harry, Teumer, A. (Alexander), T. Fall, Wolffenbuttel, B. H., Shin, S.Y., Shi, J. (Jianxin), Dorret I Boomsma, Feitosa, M.F. (Mary Furlan), Neale, B., Day, F.R. (Felix), Grallert, H., C. Pütter, Kari Stefansson, Vermeulen, S.H., Kraja, A. (Aldi), Steinthorsdottir, V., N. Amin, Khaw, KT, Hartikainen, AL, S. Schreiber, Hu, Frank B., Neale, BM, Ripatti, S, Boehm, B. O., Kees G Hovingh, Lindgren, Cecilia M, Hengstenberg, C, Mihailov, E., Chines, Peter S., Lorentzon, M. (Mattias), Lin, Dan-Yu, Pedersen, N., Erdmann, J. (Jeanette), Chasman, DI, März, W, N. Pedersen, Jennifer E Huffman, Fischer, K (Kirsten), Fox, C.S., Vilmundur Gudnason, Haritunian, T. (Talin), Signorini, S, K. G. Hovingh, Palmer, Colin N A, Medland, Sarah E., Bruinenberg, M. (M.), Thorand, B, Wilson, J.F., N. Eklund, Samani, N.J., Kathiresan, S, Jarvelin, M.-R. (Marjo-Riitta), Gerjan Navis, Raitakari, O., T. Johnson, Connell, J. M., Kleber, Marcus E., Heard Costa, N. L., Wolfgang Koenig, M. Farrall, Soranzo, N., E. Mihailov, Penninx, Brenda, Gentilini, Davide, Waeber, G., Zoltán Kutalik, Pouta, A., Widen, Elisabeth, H. Basart, Kahonen, M., Y. Hu, Perola, M. (Markus), Wichmann, HE, Hall, P., Preuss, Michael, Kuulasmaa, K. (Kari), Wolffenbuttel, B.H.R. (Bruce), Kiemeney, L.A., Beilby, J., Stephens, J. (Jonathan), Koenig, W. (Wolfgang), Cadby, G, Wilson, James F; id_orcid, S. H. Vermeulen, T. Haritunian, Spector, Timothy D., Tregouet, D.-A. (David-Alexandre), Kristiansson, K. (Kati), Kleber, M.E. (Marcus), Atalay, Mustafa, Kuh, D, König, Wolfgang, Farrall, M., Teumer, Alexander, Attwood, A.P. (Antony), Tregouet, D.A., J. Erdmann, Heath, AC, J. Virtamo, Illig, T, Lavinia, P, Cupples, L Adrienne, Wolfenbuttel, B.H.R., Cupples, L. Adrienne, Peden, John F., Cristen J Willer, Saaristo, Timo E., N. Narisu, Schreiber, S, Willemsen, G.; id_orcid, Prokopenko, I, Khaw, Kay-Tee, Lecoeur, Cecile, Basart, D.C.G. (Dick), D. Marek, Montgomery, Grant W, Kristian Hveem, Neale, B.M., Ferreira, T. (Teresa), Samani, Nilesh J, V. Mooser, Kraja, Aldi T, Damien C Croteau-Chonka, Kristiansson, Kati, P. M. Visscher, Nohr, E.A., Boomsma, Dorret I., McArdle, W.L., Hirschhorn, J.N., T. Illig, A. G. Uitterlinden, Stirrups, K, Strawbridge, R. J., Reedik Mägi, Medina-Gomez, C., Hayward, Caroline, Hu, Y. J., Gemma Cadby, Hofman, A. (Albert), H. Watkins, Eriksson, J. G., Maerz, W, Albert Hofman, Connell, J.M.C., H. Wichmann, Nohr, C. (Christian), Wild, S. H., Yang, Jiaqi, T. Esko, Evans, D.M. (David), Asselbergs, F.W., Martin, N. G., Aarno Palotie, Caulfield, MJ, Kee, Frank; id_orcid, Manunta, P., Müller-Nurasyid, Martina, Marz, W., Shin, So-Youn, Ferrario, M.M., Hovingh, K. G., Scherag, A., David M Evans, B. O. Boehm, Hu, Yi-Juan, Lavinia, P., Hottenga, J. J., Lamina, C, Kiemeney, Lambertus A, Kaplan, Robert C, K. Fischer, Hicks, AA, J. Beilby, Kuusisto, Johanna, Franke, L., Cusi, D, R. Rauramaa, Oostra, B.A., Watkins, Hugh, Christian Gieger, Magnusson, P.K.E., Keinanen-Kiukaanniemi, Sirkka M, Albrecht, E, Stirrups, Kathleen, Min, Josine L, Michael Boehnke, Jackson, A. U., Dimitriou, M., Spector, T.D., G. W. Montgomery, Lind, L. (Lars), Balmforth, A. J., Kathiresan, Sekar, Wilson, JF, Waeber, G, Thorkild I A Sørensen, Amouyel, P. (Philippe), Province, Michael A, Alena Stančáková, Y. Pawitan, Shungin, Dmitry,, Moffatt, Miriam, Wolffenbuttel, BH, Jansson, John-Olov, Abecasis, G. R., I. B. Borecki, M. M. Van der Klauw, Li, G., Absher, D., T. Workalemahu, Johnson, T. (Toby), P. K. Magnusson, Sørensen, T. I., Zillikens, MC, Lindstrom, Jaana, Goncalo R Abecasis, Froguel, P., Amouyel, P, Wheeler, E. (Eleanor), Lee, S. H., Gustafsson, S. (Stefan), Langenberg, C. (Claudia), Froguel, P, Li, G (Guo), Fox, Caroline S, Vermeulen, Sita H, P. Amouyel, Gejman, P. V., Ulf de Faire, McArdle, W. L., Aparna Radhakrishnan, Mateo Leach, I, Connell, J.M., Rivadeneira Ramirez, F. (Fernando), McKnight, Barbara, V. Gudnason, Harris, Tamara B, Pütter, Carolin, Peters, M.J., Kathiresan, S., Campbell, H. (Harry), Wheeler, E., Manunta, P, Caulfield, M. (Mark), L. J. Launer, Boehnke, M, Sanna, S, K. E. North, M. E. Kleber, Saaristo, T. (Timo), Stancakova, Alena, Joel N Hirschhorn, Wolffenbuttel, Bruce H.R., Rauramaa, R. (Rainer), Johannes Hebebrand, Palmer, Colin N. A., Keri L Monda, Hu, F.B., Tyrer, Jonathan, Huffman, Jennifer E., Langenberg, C, Njølstad, Inger, Frau, F, Borecki, Ingrid B., Peden, J. (John), Stark, K. (Klaus), Kumari, M. (Meena), Robert C Kaplan, Swift, A.J., E. E. Schadt, Laitinen, J.H., Wallaschofski, H., Schadt, EE, Lind, Lars, Vedantam, Sailaja, Melanie M Van der Klauw, Hveem, K., Martin Farrall, Mooser, Vincent, Uitterlinden, AG, Evans, DM, Illig, T. (Thomas), Gejman, Pablo V, Min, JL, Zillikens, M.C. (Carola), Tamara B Harris, Gieger, C, Ronald P Stolk, Van der Klauw, Melanie M., Chanock, Stephen J, de Vegt, Femmie, Gérard Waeber, Khaw, K-T. (Kay-Tee), Palmer, Colin N., Wichmann, H-Erich, Ouwehand, W.H. (Willem), Wong, A., Goel, Anuj, Stirrups, K., Watkins, H., S. I. Berndt, Schlessinger, D., Timothy D Spector, Narisu, N., Winkler, T.W. (Thomas), Basart, H., Croteau-Chonka, DC, Chines, P.S., Dei, Mariano, van Duijn, CM, Palotie, A, Schadt, Eric E., Dei, M. (Mariano), K. L. Mohlke, Vandenput, Liesbeth, Campbell, Harry; id_orcid, Pechlivanis, Sonali, I. Rudan, Jarvelin, M.R., Ferrario, F. (Franco), Chasman, Daniel I, Croteau-Chonka, D., Stolk, RP (Ronald), Di Blasio, A. M., Martin, NG, Nolte, IM (Ilja), Ridker, P. M., L. J. Palmer, Johnson, T., Wolffenbuttel, Bruce H R, Oldehinkel, A.J. (Albertine), Hyppoenen, E, Salomaa, V, Sambrook, J.G. (Jennifer), Jian Yang, Yang, Jian, Steinthorsdottir, V, J. R. O'Connell, Winkler, Thomas W., Zwart, J-A. (John-Anker), Saaristo, Timo E, Province, MA, Hveem, K. (Kristian), Moffatt, M.F. (Miriam), Rendon, A, Gustafsson, S., Croteau-Chonka, D.C., Palotie, A., Strawbridge, Rona J., Workalemahu, T, Jula, A. (Antti), Soranzo, N. (Nicole), Sørensen, Thorkild I. A., Kaplan, R.C. (Robert), Magnusson, PK, Prokopenko, Inga, Eklund, N, Francis S Collins, Jöckel, K-H, Peters, M.J. (Marjolein), Snieder, H, Amy J Swift, Launer, Lenore J., Fox, C. S., Van Der Klauw, M. M., Ouwehand, W. H., Wichmann, H. E., Li, G. (Guo), Loos, R.J.F. (Ruth), E. K. Speliotes, Wareham, N.J. (Nick), Nieminen, Markku S, McKnight, B. (Barbara), Kanoni, S., Marek, D., Balmforth, AJ, Luan, Jian’an, Eriksson, J.G. (Johan), Bragg Gresham, J. L., Kiemeney, L.A.L.M. (Bart), Chines, Peter S, Pütter, C. (Carolin), Esko, T, Nicholas J Wareham, Cookson, W.O. (William), Claudia Langenberg, Jöckel, K.-H. (Karl-Heinz), Eklund, N. (Niina), Kuh, D., Goel, A., Tremoli, E, A. Palotie, Vincent Mooser, N. J. Samani, Theodoraki, Eirini V., J. C. Stephens, Erdmann, J., Oldehinkel, Albertine J., A. A. Hicks, Absher, Devin, A. Goel, Balmforth, Anthony J, van der Harst, Pim, Nicholson, G. (Ggeorge), Leach, IM, Koenig, W, Faire, U. de, Homuth, G., Morris, A.D., A. Tönjes, Mika Kähönen, H-Erich Wichmann, Asselbergs, F. W., Van der Klauw, Melanie M; id_orcid, Uitterlinden, A. G., Justice, Anne E., Berndt, S. I., Kraja, A.T., Njolstad, Inger, Mooser, V. (Vincent), John M Connell, Mihailov, E, Musk, A.W. (Arthur), W. H. Ouwehand, Pim van der Harst, Tyrer, J., Cupples, LA, A. Metspalu, Beilby, John, Bruce M Psaty, Palmer, C. (Cameron), Cookson, William, Jula, A, McCarthy, M.I., Waeber, Gerard, John F Peden, Pechlivanis, S., Polasek, O., Morris, Andrew P., Cupples, L. A., Sang Hong Lee, A. Hofman, P. M. Ridker, Ong, Ken K., Lakka, T.A. (Timo), F. R. Day, André Scherag, Mühleisen, TW, Collins, Francis S., Sinisalo, Juha, Fischer, Krista, Homuth, Georg, Harris, TB, B. M. Neale, Deloukas, Panos, Jarick, Ivonne, Lind, L, Franke, L. (Lude), Rendon, A., Wareham, Nicholas J., Chanock, SJ, O'Connell, J.R., Nohr, Ellen A., K. Estrada, Li, Guo, Abecasis, GR, Oostra, B.A. (Ben), Croteau-Chonka, Damien C., Winfried März, Heijer, MD, Speliotes, EK, Karpe, Fredrik, Jonathan Tyrer, Skrobek, B, Zhao, J.H., Pütter, C, Berndt, SI, Koenig, IR, Croteau-Chonka, D.C. (Damien), K. Kristiansson, Vitart, V, M. Lorentzon, Liang, L. (Liming), Evans, David M., Hayward, C, Putter, C., Yudi Pawitan, Rona J Strawbridge, Kanoni, Stavroula, Borecki, I.B. (Ingrid), Sørensen, Thorkild I A, Assimes, Themistocles L, Berndt, S., Vedantam, S, Gyllensten, U. (Ulf), Strachan, DP, Gentilini, D, Rauramaa, R., Assimes, TL, Moffatt, Miriam F., Themistocles L Assimes, Schadt, Eric E, Spector, TD, Atalay, M. (Mustafa), Tregouet, D-A, Igor Rudan, Speliotes, E. K., W. L. McArdle, Cookson, William O., Heijer, M. D., Ong, K. (Ken), Lindgren, C. M., Loos, Ruth J., Radhakrishnan, A, Berndt, S.I., Hall, P, Lin, D.Y. (Dan), Nieminen, M.S., Trip, Mieke D, S. Shin, Hartikainen, A.L., Connell, JM, van Meurs, JB, Jouke-Jan Hottenga, Jacobs, K. B., Oostra, B. A., A. Stančáková, Jacobs, K.B., Hveem, Kristian, Frau, F. (Francesca), Strachan, D. P., Njolstad, I, Timo A Lakka, Gustafsson, Stefan,, Leach, I.M., J. C. M. Witteman, Tönjes, A, Theodoraki, EV, Peden, JF, Magnusson, P.K., Vliet-Ostaptchouk, J.V. (Jana) van, Liang, L., Peters, A. (Annette), Rendon, A. (Augusto), Lehtimäki, T, Strachan, David P, Hunter, David, T. W. Winkler, Lakka, T. A., Abecasis, G.R. (Gonçalo), Wang, Zhaoming, Puetter, C, Speliotes, Elizabeth K, Spector, T. D., Hinney, A. (Anke), Hunt, SE, Madden, P.A. (Pamela), Samani, Nilesh J., Trip, M. D., Penninx, B, Campbell, H, Virtamo, J, Chines, P.S. (Peter), Hofman, Bert, Wright, A. F., Cadby, Gemma, Langenberg, Claudia, Watkins, H, Keinanen-Kiukaanniemi, S. (Sirkka), Van Duijn, C. M., Heath, A.C. (Andrew), G. Homuth, Eriksson, Johan G., Palmer, C.N.A., Justice, AE, Paul W Franks, Feitosa, Mary F., Eklund, Niina, Michael Stumvoll, Wood, A.R. (Andrew), Jorma Viikari, Snieder, H., Justice, A., Sinisalo, J. (Juha), Heid, IM, Wichmann, H.-Erich, Dei, M., Kay-Tee Khaw, Uitterlinden, André, S. E. Medland, Pouta, Anneli, Medland, Sarah E, Khaw, K-T, Stark, K., Lorentzon, Mattias, Kleber, ME, Anke Tönjes, Stephens, JC, Gieger, C., Surakka, I. (Ida), North, K.E. (Kari), Stolk, Ronald P., Iribarren, C, Tönjes, A., T. E. Saaristo, Ridker, Paul M, Saaristo, T. E., Province, M.A., Milani, L. (Lili), David Meyre, Hunter, D. (David), Power, C., Leach, I.M. (Irene Mateo), Johansson, A, Gudmar Thorleifsson, Edkins, T. (Ted), Grallert, Harald, Stefano Signorini, Peters, Marjolein J, J. Yang, M. J. Peters, Jarvelin, M-R, Workalemahu, T., G. Cadby, König, I. R., Lindsay L Waite, K. K. Ong, S. E. Hunt, Patricia B Munroe, Stephens, J.C., S. Edkins, Keinanen-Kiukaanniemi, S.M., Hovingh, Kees G., Mangino, Massimo, Lokki, M.L., Hicks, A.A. (Andrew), Lyle J Palmer, Ripatti, S. (Samuli), Hunt, S.E. (Sarah), J. H. Laitinen, Wild, S.H., Gonneke Willemsen, Liang, LM, Abecasis, Goncalo R., Albert Vernon Smith, Bernhard R Winkelmann, Ferreira, T, Hamsten, A. (Anders), James F Wilson, O Cookson, W, Stefansson, K., van Meurs, J.B., Meyre, David, Markku S Nieminen +999 morecore +1 more sourceFrom mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato +2 morewiley +1 more sourceHigh impact activity is related to lean but not to fat mass: findings from a population-based study in adolescents [PDF]
, 2012 Background: Objective measures of physical activity calibrated against energy expenditure may have limited utility in studying relationships with musculoskeletal phenotypes.Rittweger, Jörn, Deere, Kevin, Tobias, Jonathan H, Davey Smith, George, Tobias, Jon, Sayers, Adrian +5 morecore +1 more sourceSubtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan +6 morewiley +1 more sourceInterleukin-15 modulates adipose tissue by altering mitochondrial mass and activity. [PDF]
PLoS ONE, 2014 Interleukin-15 (IL-15) is an immunomodulatory cytokine that affects body mass regulation independent of lymphocytes; however, the underlying mechanism(s) involved remains unknown.Nicole G Barra, Rengasamy Palanivel, Emmanuel Denou, Marianne V Chew, Amy Gillgrass, Tina D Walker, Josh Kong, Carl D Richards, Manel Jordana, Stephen M Collins, Bernardo L Trigatti, Alison C Holloway, Sandeep Raha, Gregory R Steinberg, Ali A Ashkar +14 moredoaj +1 more sourcePre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan +11 morewiley +1 more sourceBody composition and appetite : fat-free mass (but not fat mass or BMI) is positively associated with self-determined meal size and daily energy intake in humans [PDF]
, 2011 The idea of body weight regulation implies that a biological mechanism exerts control over energy expenditure and food intake. This is a central tenet of energy homeostasis.Finlayson, Graham, Finlayson, G, King, NA, Naslund, Erik, Mark Hopkins, Naslund, E, Caudwell, P, Blundell, JE, Gibbons, C, Hopkins, M, Hopkins, Mark, Graham Finlayson, Blundell, John E., Phillipa Caudwell, Gibbons, Catherine, John E. Blundell, King, Neil A., Catherine Gibbons, Erik Näslund, Neil A. King, Caudwell, Phillipa +20 morecore +1 more source
