Clinical Insights Into Hypercalcemia of Malignancy in Childhood
ABSTRACT Hypercalcemia of malignancy (HCM) is a rare but life‐threatening metabolic emergency in children that occurs in less than 1% of pediatric cancer cases, with a reported incidence ranging from 0.4% to 1.0% across different studies. While it is observed in 10%–20% of adult malignancies, pediatric HCM remains relatively uncommon.
Hüseyin Anıl Korkmaz
wiley +1 more source
Enzyme activity, hormone concentration in tree shrew (Tupaia belangeri) during cold acclimation [PDF]
Environmental factors play an important role in the seasonal adaptation of body mass and thermogenesis in wild small mammals. The tree shrew (Tupaia belangeri), is a unique species of small mammals which is origin of island in the Oriental realm.
Lin Zhang, Wanlong Zhu, Zhengkun Wang
doaj
Developmental Expression of \u3cem\u3eDrop-Dead\u3c/em\u3e is Required for Early Adult Survival and Normal Body Mass in \u3cem\u3eDrosophila melanogaster\u3c/em\u3e [PDF]
In Drosophila melanogaster, mutations in the gene drop-dead (drd) result in early adult lethality, with flies dying within 2 weeks of eclosion. Additional phenotypes include neurodegeneration, tracheal defects, starvation, reduced body mass, and female ...
Blumenthal, Edward M +1 more
core +1 more source
Circadian Disruption and Metabolic Disease: Findings from Animal Models [PDF]
Social opportunities and work demands have caused humans to become increasingly active during the late evening hours, leading to a shift from the predominantly diurnal lifestyle of our ancestors to a more nocturnal one.
Arble, Deanna M. +3 more
core +2 more sources
ABSTRACT Introduction Pulmonary dysfunction and sleep abnormalities are common in children with sickle cell disease (SCD) and are associated with worse clinical outcomes. Whether spirometry abnormalities are associated with polysomnography (PSG) findings remains unclear.
Ammar Saadoon Alishlash +4 more
wiley +1 more source
Prevalence and Trajectory of Household Material Hardship Among Children With Advanced Cancer
ABSTRACT Background/Objectives Families of children with advanced cancer living in poverty experience inferior outcomes including poor parent mental health and worse child quality of life. Household material hardship (HMH: food, housing, transportation, and/or utility insecurity) is a modifiable poverty exposure—and potential intervention target—that ...
Sarah Wright +13 more
wiley +1 more source
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley +1 more source
Circadian and Metabolic Effects of Light: Implications in Weight Homeostasis and Health [PDF]
Daily interactions between the hypothalamic circadian clock at the suprachiasmatic nucleus (SCN) and peripheral circadian oscillators regulate physiology and metabolism to set temporal variations in homeostatic regulation.
Diego A. Golombek +6 more
core +2 more sources
Nonspecific Energy Expenditure of the Body and Body Mass Regulation
The principal possibility of nonspecific energy expenditure at all stages of the transformation of nutrients in the body is demonstrated. These stages include the processing of food in the mouth, digestion, absorption, interaction with the intestinal micro biome, and interstitial metabolic processes.
openaire +2 more sources
Non‐hematopoietic effects of endogenous erythropoietin on lean mass and body weight regulation [PDF]
ObjectiveTo investigate the concurrent relationships between human plasma erythropoietin concentrations and energy expenditure (EE), body composition, plasma leptin concentrations, and associations with weight change.MethodsPlasma to measure erythropoietin and leptin; data for body composition; 24‐h EE measured in a whole‐room calorimeter; and 75 g ...
Martin, Reinhardt +5 more
openaire +2 more sources

