Results 51 to 60 of about 602,092 (255)

Effects of Exogenous Melatonin on Body Mass Regulation and Hormone Concentrations in Eothenomys miletus [PDF]

Journal of Stress Physiology & Biochemistry, 2013
By regulating the pineal hormone, photoperiods affect many physiological characteristics in small mammals. Thus, melatonin might take part in the thermoregulation of seasonal variations in small mammals.
Zhu, Wan-Long, Zhang, Di, Zhang, Lin, Wang, Zheng-Kun   +3 more
doaj  

Effects of real and simulated weightlessness on the cardiac and peripheral vascular functions of humans: A review

International Journal of Occupational Medicine and Environmental Health, 2015
Weightlessness is an extreme environment that can cause a series of adaptive changes in the human body. Findings from real and simulated weightlessness indicate altered cardiovascular functions, such as reduction in left ventricular (LV) mass, cardiac ...
Hui Zhu, Hanqing Wang, Zhiqiang Liu
doaj   +1 more source

Body weight homeostat that regulates fat mass independently of leptin in rats and mice [PDF]

Proceedings of the National Academy of Sciences, 2017
Significance The only known homeostatic regulator of fat mass is the leptin system. We hypothesized that there is a second homeostat regulating body weight with an impact on fat mass. In this study we have added and removed weight loads from experimental animals and measured the effects on the biological body weight.
John-Olov Jansson, Vilborg Palsdottir, Daniel A. Hägg, Erik Schéle, Suzanne L. Dickson, Fredrik Anesten, Tina Bake, Mikael Montelius, Jakob Bellman, Maria E. Johansson, Roger D. Cone, Daniel J. Drucker, Jianyao Wu, Biljana Aleksic, Anna E. Törnqvist, Klara Sjögren, Jan-Åke Gustafsson, Sara H. Windahl, Claes Ohlsson   +18 more
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Non‐hematopoietic effects of endogenous erythropoietin on lean mass and body weight regulation [PDF]

Obesity, 2016
ObjectiveTo investigate the concurrent relationships between human plasma erythropoietin concentrations and energy expenditure (EE), body composition, plasma leptin concentrations, and associations with weight change.MethodsPlasma to measure erythropoietin and leptin; data for body composition; 24‐h EE measured in a whole‐room calorimeter; and 75 g ...
Martin, Reinhardt, Soumyadeep, Dey, Constance, Tom Noguchi, Yuanyuan, Zhang, Jonathan, Krakoff, Marie S, Thearle   +5 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Effect of sodium butyrate on diet-induced obesity in the Sprague-Dawley rat

浙江大学学报. 农业与生命科学版, 2015
Obesity has been reported as an increasingly prevalent and highly heritable health problem leading to increased risks for several common diseases. Human obesity can be induced by genetic factors such as loss-of-function mutations in individual genes. The
Zhu Han, Tan Shasha, Yang Hong, Wang Ling   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Regulation of food provisioning in the Antarctic petrel; the importance of parental body condition and chick body mass [PDF]

Journal of Animal Ecology, 1998
1. Two hypotheses may explain how long‐lived seabirds regulate the food provisioning to their chick. The fixed level of investment hypothesis states that the parents provide food for their chick according to an intrinsic rhythm, independent of their chick's need.
Torkild Tveraa, Bernt‐Erik Sether, Ronny Aanes, Kjell Einar Erikstad   +3 more
openaire   +1 more source