Results 51 to 60 of about 609,357 (298)

Two New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for Early-Onset Extreme Obesity in French and German Study Groups [PDF]

, 2010
Meta-analyses of population-based genome-wide association studies (GWAS) in adults have recently led to the detection of new genetic loci for obesity. Here we aimed to discover additional obesity loci in extremely obese children and adolescents.
Marjo-Riitta Jarvelin, Martin Klingenspor, Heude, Barbara, Lévy-Marchal, C., Wichmann HE, Balkau, B, Hebebrand, J., Schürmann, A., Kiess, W., Fromme Tobias, Hartikainen, A.L., Rosskopf D, Erbel, R., Schulz N, Klingenspor Martin, Wichmann, H.-E., Schäfer H, Illig Thomas, Joeckel, Karl-Heinz, Fisher E, Johannes Hebebrand, Vogel, Carla I. G., Schulz, N, Jacques Weill, Hartikainen Anna-Liisa, Körner, A, Nöthen, MM, Krude Heiko, Borte, M, Scherag André, Froguel Philippe, Winfried Rief, Hinney A, Nöthen, M.M., Klingenspor, Martin, Hartikainen AL, Boeing Heiner, Schaefer, Helmut, Schulz, N., Rayner, Nigel W., Borte, Michael, Balkau, B., Rosskopf Dieter, Moebus, Susanne, Heinrich, Joachim, Harald Grallert, Hebebrand J, Heinrich, J., Thomas W Mühleisen, Rzehak, Peter, Klingenspor, M, Scherag S, Grallert, H., Hinney, A., Fromme, T., Vogel CI, Moebus, S, Rayner NW, Erbel, R, Dieter Rosskopf, Reinehr, T., Hartikainen, Anna-Liisa, Scherag A, Vogel, CIG, Eva Fisher, Jarvelin, Marjo-Riitta, Hartikainen, AL, Biebermann, Heike, Mühleisen TW, Vatin, V, Noethen, Markus M., Nigel W Rayner, Wichmann, H-E, Grallert H, Inga Prokopenko, Dina, C., Jarick Ivonne, Rief W, Vogel, CI, Mueller, Timo D., Prokopenko I, Berdel Dietrich, David Meyre, Berdel, D., Jarvelin, M.R., Hebebrand, Johannes, Borte Michael, Reinehr, T, Schulz Nadja, Grallert, Harald, Jarvelin, M-R, Vatin, Vincent, Joeckel, K-H, Schaefer, H, Meyre D, Jarvelin MR, Fisher Eva, Boes Tanja, Heude, B, Fisher, E, Levy-Marchal, Claire, Heiko Krude, Vogel, C.I.G., Borte M, McCarthy, MI, Koerner, Antje, Karl-Heinz Jöckel, McCarthy Mark I., Boeing H, Noethen, MM, Erbel, Raimund, Wichmann, HE, Heinrich, J, Illig T, Peter Rzehak, Jarvelin Marjo-Riitta, Mýhleisen TW, Grallert Harald, Thomas Illig, Weill, J, Levy-Marchal, C, Heude Barbara, Kovacs Peter, Jöckel, KH, Kovacs, P, Heude B, Prokopenko, Inga, Meyre, David, Rzehak Peter, Fromme, Tobias, Vogel Carla I. G., McCarthy, Mark I., Krude, H, Berdel, D, Kiess, W, Mühleisen Thomas W., Rief, W., Froguel P, Boeing, Heiner, Claire Levy-Marchal, McCarthy MI, Biebermann H, Illig, T, Mueller, TD, Christian Rimmbach, Scherag Susann, Tanja Boes, Carla I G Vogel, Vatin, V., Fisher, Eva, Heude, B., Prokopenko, I, Heike Biebermann, Reinehr Thomas, Hinney, A, Ivonne Jarick, Heiner Boeing, Christian Dina, Moebus, S., Delplanque J, Kovacs, P., Dina Christian, Fromme T, Illig, T., Weill, Jacques, Rosskopf, Dieter, Fisher, E., Reinehr, Thomas, Jöckel KH, Boes, T, Nadja Schulz, Kovacs, Peter, Moebus S, Schýrmann A, Muehleisen, TW, Heinrich Joachim, Raimund Erbel, Rosskopf, D., Prokopenko, I., Körner Antje, Scherag, Susann, Rimmbach, Christian, Dina C, Antje Körner, Koerner, A, Hebebrand, J, Scherag, S., Scherag, A, Rzehak, P., Thomas Reinehr, Rief, Winfried, Boeing, H, Reinehr T, Klingenspor M, Helmut Schäfer, Scherag, S, Schäfer, H, H-Erich Wichmann, Schäfer, H., Hebebrand Johannes, Meyre David, Rayner, N.W., Kiess, Wieland, Anke Hinney, Hinney Anke, Scherag, Andre, Meyre, D, Rosskopf, D, Hinney, Anke, Biebermann, H., Susanne Moebus, Körner A, Scherag, A., Levy-Marchal C, Müller, T.D., Delplanque, Jerome, Rief Winfried, Muehleisen, Thomas W., Müller TD, Krude, H., Rimmbach, C, Jöckel, K.-H., Rzehak P, Berdel D, Philippe Froguel, Biebermann, H, Wichmann, Heinz-Erich, Rief, W, Anna-Liisa Hartikainen, Barbara Heude, McCarthy, M.I., Jarvelin, MR, André Scherag, Jérôme Delplanque, Rayner, NW, Boes, T., Jarick I, Beverley Balkau, Rimmbach, C., Mühleisen, T.W., Mühleisen, TW, Vatin Vincent, Vincent Vatin, Hartikainen, A-L, Moebus Susanne, Schürmann, A, Delplanque, J, Michael Borte, Balkau, Beverley, Susann Scherag, Boes T, Balkau Beverley, Jarick, Ivonne, Boes, Tanja, Müller, TD, Prokopenko Inga, Borte, M., Annette Schürmann, Krude H, Berdel, Dietrich, Nöthen Markus M., Jarick, I, Müller Timo D., Schulz, Nadja, Wichmann H.-Erich, Dina, Christian, Dina, C, Mýller TD, Froguel, Philippe, Weill Jacques, Fromme, T, Rimmbach C, Grallert, H, Schuermann, Annette, Mark I McCarthy, Schäfer Helmut, Weill, J., Delplanque Jérôme, Rayner Nigel W., Kiess Wieland, Illig, Thomas, Timo D Müller, Joachim Heinrich, Balkau B, Vatin V, Tobias Fromme, Rzehak, P, Schürmann Annette, Kiess W, Körner, A., Nöthen MM, Levy-Marchal Claire, Kovacs P, Markus M Nöthen, Erbel Raimund, Wieland Kiess, Erbel R, Heinrich J, Dietrich Berdel, Klingenspor, M., Jarick, I., Schürmann A, Rimmbach Christian, Boeing, H., Froguel, P., Peter Kovacs, Krude, Heiko, Weill J, Schuermann, A, Delplanque, J., Jöckel Karl-Heinz, Biebermann Heike, Meyre, D., Froguel, P   +313 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Identification of TUB as a novel candidate gene influencing body weight in humans [PDF]

, 2006
Previously, we identified a locus on 11p influencing obesity in families with type 2 diabetes. Based on mouse studies, we selected TUB as a functional candidate gene and performed association studies to determine whether this controls obesity.
Feskens, E., Shiri-Sverdlov, R.; id_orcid, van Gorp, P.J., Feskens, E.J., van Tilburg, J.H.O., Shiri-Sverdlov, R., Koeleman, B.P., van Haeften, T.W., Wijmenga, C., Dolle, M.E., Vliet-Ostaptchouk, J.V., Dolle, M.E.T., Hofker, M.H., van Gorp, P.J.J.; id_orcid, van der A, A.D., Koeleman, B.P.C., van Vliet-Ostaptchouk, J.V., Custers, A., van Tilburg, J.H., Lindsey, P.J., Feskens, E.J.M., van Gorp, P.J.J., Wijmenga, C.; id_orcid, Zhernakova, S., van der A, D.L.   +24 more
core   +1 more source

Emotional regulation and self-perceived quality of life in high-performance mountain sports athletes

Frontiers in Psychology
Emotional regulation is an indispensable capacity for human beings, so that alterations in it can lead to the appearance of psychological, social and/or cognitive disorders. Therefore, possessing adequate emotional strategies is intimately related to the
Pablo Rojo-Ramos, Carmen Galán-Arroyo, Santiago Gómez-Paniagua, Antonio Castillo-Paredes, Jorge Rojo-Ramos   +4 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Studies on seasonal variation in metabolic rate related to changes in body composition with particular reference to shorebirds (Charadrii) [PDF]

, 1992
The basal metabolic rate of three species of shorebird was measured throughout the non-breeding season. These measurements were related to change in body mass and body composition.
Scott, Ian Alexander
core  

Effects of real and simulated weightlessness on the cardiac and peripheral vascular functions of humans: A review

International Journal of Occupational Medicine and Environmental Health, 2015
Weightlessness is an extreme environment that can cause a series of adaptive changes in the human body. Findings from real and simulated weightlessness indicate altered cardiovascular functions, such as reduction in left ventricular (LV) mass, cardiac ...
Hui Zhu, Hanqing Wang, Zhiqiang Liu
doaj   +1 more source

Nonspecific Energy Expenditure of the Body and Body Mass Regulation

Journal of Nutritional Biology, 2019
The principal possibility of nonspecific energy expenditure at all stages of the transformation of nutrients in the body is demonstrated. These stages include the processing of food in the mouth, digestion, absorption, interaction with the intestinal micro biome, and interstitial metabolic processes.
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Body Temperature and Activity Adaptation of Short Photoperiod-Exposed Djungarian Hamsters (Phodopus sungorus): Timing, Traits, and Torpor

Frontiers in Physiology, 2021
To survive the Siberian winter, Djungarian hamsters (Phodopus sungorus) adjust their behavior, morphology, and physiology to maintain energy balance.
Elena Haugg, Annika Herwig, Victoria Diedrich   +2 more
doaj   +1 more source