Results 61 to 70 of about 8,859,342 (293)

ANALYSIS OF THE EFFECT OF NUTRITION, PHYSIOLOGICAL FACTORS, AND BODY COMPONENTS ON EXTREME PATTERNS OF BODY MASS INDEX [PDF]

Assiut Veterinary Medical Journal
The body mass index (BMI) is one of the most commonly used indicators to assess nutritional status and classify individuals into thin, normal weight, overweight, and obese. However, recent evidence indicates that relying on it alone may not be sufficient
PARY AMEER, TAHA MOHAMMED, MOHAMMED AGA
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Effects of real and simulated weightlessness on the cardiac and peripheral vascular functions of humans: A review

International Journal of Occupational Medicine and Environmental Health, 2015
Weightlessness is an extreme environment that can cause a series of adaptive changes in the human body. Findings from real and simulated weightlessness indicate altered cardiovascular functions, such as reduction in left ventricular (LV) mass, cardiac ...
Hui Zhu, Hanqing Wang, Zhiqiang Liu
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Non‐hematopoietic effects of endogenous erythropoietin on lean mass and body weight regulation [PDF]

Obesity, 2016
ObjectiveTo investigate the concurrent relationships between human plasma erythropoietin concentrations and energy expenditure (EE), body composition, plasma leptin concentrations, and associations with weight change.MethodsPlasma to measure erythropoietin and leptin; data for body composition; 24‐h EE measured in a whole‐room calorimeter; and 75 g ...
Martin, Reinhardt, Soumyadeep, Dey, Constance, Tom Noguchi, Yuanyuan, Zhang, Jonathan, Krakoff, Marie S, Thearle   +5 more
openaire   +2 more sources

Chronotype predicts body mass index via emotion regulation strategy use and emotional eating

, 2023
An individual’s orientation towards mornings or evenings, referred to as chronotype, is predictive of both physical and mental health outcomes. An evening chronotype is associated with elevated body mass index and a less nutritious diet.
Robert C.A. Bendall, Bendall, Robert C.A., Keenan, Gregory S., Gregory S. Keenan   +3 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Effect of sodium butyrate on diet-induced obesity in the Sprague-Dawley rat

浙江大学学报. 农业与生命科学版, 2015
Obesity has been reported as an increasingly prevalent and highly heritable health problem leading to increased risks for several common diseases. Human obesity can be induced by genetic factors such as loss-of-function mutations in individual genes. The
Zhu Han, Tan Shasha, Yang Hong, Wang Ling   +3 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source