Results 1 to 10 of about 1,113,790 (268)

Prostaglandin Transporter OATP2A1/SLCO2A1 Is Essential for Body Temperature Regulation during Fever [PDF]

open access: bronzeJ Neurosci, 2018
Prostaglandin E2 (PGE2) in the hypothalamus is a principal mediator of the febrile response. However, the role of organic anion transporting polypeptide 2A1 (OATP2A1/SLCO2A1), a prostaglandin transporter, in facilitating this response is unknown.
Y. Nakamura   +9 more
semanticscholar   +4 more sources

Transient receptor potential melastatin 8 (TRPM8) channels are involved in body temperature regulation [PDF]

open access: goldMol Pain, 2012
BackgroundTransient receptor potential cation channel subfamily M member 8 (TRPM8) is activated by cold temperature in vitro and has been demonstrated to act as a ‘cold temperature sensor’ in vivo.
N. Gavva   +5 more
semanticscholar   +4 more sources

Estradiol alters body temperature regulation in the female mouse [PDF]

open access: yesTemperature (Austin), 2018
Hot flushes are due to estrogen withdrawal and characterized by the episodic activation of heat dissipation effectors. Recent studies (in humans and rats) have implicated neurokinin 3 (NK3) receptor signaling in the genesis of hot flushes.
Sally J Krajewski-Hall   +3 more
semanticscholar   +2 more sources

Body temperature regulation in diabetes [PDF]

open access: yesTemperature (Austin), 2016
The effects of type 1 and type 2 diabetes on the body's physiological response to thermal stress is a relatively new topic in research. Diabetes tends to place individuals at greater risk for heat-related illness during heat waves and physical activity ...
G. Kenny, R. Sigal, R. Mcginn
semanticscholar   +2 more sources

Preoptic leptin signaling modulates energy balance independent of body temperature regulation [PDF]

open access: yesElife, 2018
The adipokine leptin acts on the brain to regulate energy balance but specific functions in many brain areas remain poorly understood. Among these, the preoptic area (POA) is well known to regulate core body temperature by controlling brown fat ...
Sangho Yu   +15 more
semanticscholar   +2 more sources

Body Temperature Regulation in Hot Environments [PDF]

open access: yesPLoS One, 2016
Organisms in hot environments will not be able to passively dissipate metabolically generated heat. Instead, they have to revert to evaporative cooling, a process that is energetically expensive and promotes excessive water loss. To alleviate these costs,
Jan‐Åke Nilsson   +2 more
semanticscholar   +2 more sources

Regulation of body temperature and brown adipose tissue thermogenesis by bombesin receptor subtype-3.

open access: greenAmerican Journal of Physiology. Endocrinology and Metabolism, 2014
Bombesin receptor subtype-3 (BRS-3) regulates energy homeostasis, with Brs3 knockout (Brs3(-/y)) mice being hypometabolic, hypothermic, and hyperphagic and developing obesity.
Dalya M. Lateef   +3 more
semanticscholar   +3 more sources

Cooling rates and body temperature regulation of hibernating echidnas (Tachyglossus aculeatus) [PDF]

open access: bronzeJournal of Experimental Biology, 2007
SUMMARY Echidnas (Tachyglossus aculeatus) are amongst the largest deep hibernators, but it is difficult to get them to hibernate normally under laboratory conditions.
S. Nicol, N. Andersen
semanticscholar   +2 more sources

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