Body Temperature Regulation in Hot Environments. [PDF]
Organisms in hot environments will not be able to passively dissipate metabolically generated heat. Instead, they have to revert to evaporative cooling, a process that is energetically expensive and promotes excessive water loss. To alleviate these costs,
Jan-Åke Nilsson+2 more
doaj +6 more sources
Preoptic leptin signaling modulates energy balance independent of body temperature regulation [PDF]
The adipokine leptin acts on the brain to regulate energy balance but specific functions in many brain areas remain poorly understood. Among these, the preoptic area (POA) is well known to regulate core body temperature by controlling brown fat ...
Sangho Yu+15 more
doaj +4 more sources
Regulation of Body Temperature by the Nervous System [PDF]
The regulation of body temperature is one of the most critical functions of the nervous system. Here we review our current understanding of thermoregulation in mammals. We outline the molecules and cells that measure body temperature in the periphery, the neural pathways that communicate this information to the brain, and the central circuits that ...
Chan Lek Tan, Zachary A. Knight
semanticscholar +6 more sources
Transient receptor potential melastatin 8 (TRPM8) channels are involved in body temperature regulation [PDF]
Background Transient receptor potential cation channel subfamily M member 8 (TRPM8) is activated by cold temperature in vitro and has been demonstrated to act as a ‘cold temperature sensor’ in vivo.
Gavva Narender R+5 more
doaj +3 more sources
Body temperature regulation in diabetes [PDF]
The effects of type 1 and type 2 diabetes on the body's physiological response to thermal stress is a relatively new topic in research. Diabetes tends to place individuals at greater risk for heat-related illness during heat waves and physical activity due to an impaired capacity to dissipate heat.
Ronald J. Sigal+2 more
openaire +3 more sources
Prostaglandin Transporter OATP2A1/SLCO2A1 Is Essential for Body Temperature Regulation during Fever [PDF]
Prostaglandin E2 (PGE2) in the hypothalamus is a principal mediator of the febrile response. However, the role of organic anion transporting polypeptide 2A1 (OATP2A1/SLCO2A1), a prostaglandin transporter, in facilitating this response is unknown.
Yoshinobu Nakamura+9 more
openalex +2 more sources
Temperature Regulation During Exercise and the Individual Differences [PDF]
Humans are homeotherms and can only maintain a limited range of body temperatures under hypothermic or hyperthermic conditions. During exercise, the body requires significant energy supplied by ATP within the cells.
Chen Duowen
doaj +3 more sources
Body Temperature Regulation During Exercise and Hyperthermia in Diabetics [PDF]
Thermoregulatory function, that is, heat dissipative responses such as skin blood flow (SkBF) and sweating to an increased body temperature, is critical during physical work or exercise in warm and hot conditions and during hyperthermia. Thermoregulatory
Okazaki, Kazunobu, Takeda, Ryosuke
core +3 more sources
Body temperature and its regulation
Abstract Humans are homeotherms, i.e. they fix their temperature regardless of their environment. This is vital for normal cellular function and for metabolism to be independent of external temperature. The body has a warm ‘core’ and a cooler peripheral ‘shell’ whose role is to regulate heat transfer in and out of the core.
Andrew D. Farmery+3 more
openaire +4 more sources
Regulation of body temperature and brown adipose tissue thermogenesis by bombesin receptor subtype-3
Bombesin receptor subtype-3 (BRS-3) regulates energy homeostasis, with Brs3 knockout (Brs3(-/y)) mice being hypometabolic, hypothermic, and hyperphagic and developing obesity.
Dalya M. Lateef+3 more
openalex +3 more sources