Body Temperature Regulation in Hot Environments. [PDF]
PLoS ONE, 2016Organisms in hot environments will not be able to passively dissipate metabolically generated heat. Instead, they have to revert to evaporative cooling, a process that is energetically expensive and promotes excessive water loss. To alleviate these costs,
Jan-Åke Nilsson+2 more
doaj +7 more sources
Transient receptor potential melastatin 8 (TRPM8) channels are involved in body temperature regulation [PDF]
Molecular Pain, 2012Background Transient receptor potential cation channel subfamily M member 8 (TRPM8) is activated by cold temperature in vitro and has been demonstrated to act as a ‘cold temperature sensor’ in vivo.
Gavva Narender R+5 more
doaj +5 more sources
Body temperature regulation in diabetes. [PDF]
Temperature (Austin), 2016The effects of type 1 and type 2 diabetes on the body's physiological response to thermal stress is a relatively new topic in research. Diabetes tends to place individuals at greater risk for heat-related illness during heat waves and physical activity ...
Kenny GP, Sigal RJ, McGinn R.
europepmc +5 more sources
Prostaglandin Transporter OATP2A1/SLCO2A1 Is Essential for Body Temperature Regulation during Fever. [PDF]
J Neurosci, 2018Prostaglandin E2 (PGE2) in the hypothalamus is a principal mediator of the febrile response. However, the role of organic anion transporting polypeptide 2A1 (OATP2A1/SLCO2A1), a prostaglandin transporter, in facilitating this response is unknown.
Nakamura Y+9 more
europepmc +4 more sources
Preoptic leptin signaling modulates energy balance independent of body temperature regulation [PDF]
eLife, 2018The adipokine leptin acts on the brain to regulate energy balance but specific functions in many brain areas remain poorly understood. Among these, the preoptic area (POA) is well known to regulate core body temperature by controlling brown fat ...
Sangho Yu+15 more
doaj +3 more sources
Regulation of Body Temperature by the Nervous System [PDF]
Neuron, 2018The regulation of body temperature is one of the most critical functions of the nervous system. Here we review our current understanding of thermoregulation in mammals. We outline the molecules and cells that measure body temperature in the periphery, the neural pathways that communicate this information to the brain, and the central circuits that ...
Chan Lek Tan, Z. Knight
semanticscholar +6 more sources
Thermo‐TRP regulation by endogenous factors and its physiological function at core body temperature [PDF]
Physiological ReportsTransient receptor potential (TRP) channels with temperature sensitivities (thermo‐TRPs) are involved in various physiological processes. Thermo‐TRPs that detect temperature changes in peripheral sensory neurons possess indispensable functions in ...
Makiko Kashio
doaj +3 more sources
Estradiol alters body temperature regulation in the female mouse. [PDF]
Temperature (Austin), 2018Hot flushes are due to estrogen withdrawal and characterized by the episodic activation of heat dissipation effectors. Recent studies (in humans and rats) have implicated neurokinin 3 (NK3) receptor signaling in the genesis of hot flushes.
Krajewski-Hall SJ+3 more
europepmc +2 more sources
Body temperature regulation: Sasang typology-based perspective [PDF]
Integrative Medicine Research, 2015Global warming induces a dramatic elevation of heat-related morbidity and mortality worldwide. Individual variation of heat stress vulnerability depends on various factors such as age, gender, living area and conditions, health status, and individual ...
Duong Duc Pham, Chae Hun Leem
doaj +2 more sources
Body temperature and its regulation
Anaesthesia & Intensive Care Medicine, 2018Abstract Humans are homeotherms, i.e. they fix their temperature regardless of their environment. This is vital for normal cellular function and for metabolism to be independent of external temperature. The body has a warm ‘core’ and a cooler peripheral ‘shell’ whose role is to regulate heat transfer in and out of the core.
J. Kuht, A. Farmery
semanticscholar +4 more sources