Results 81 to 90 of about 1,220,538 (359)

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

Molecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina, Viviana Bazan, Nadia Barraco, Simona Taverna, Mauro Manno, Samuele Raccosta, Anna Paola Carreca, Marco Bono, Tancredi Didier Bazan Russo, Francesco Pepe, Pasquale Pisapia, Lorena Incorvaia, Giuseppe Badalamenti, Giancarlo Troncone, Umberto Malapelle, Daniele Santini, Antonio Russo, Antonio Galvano   +17 more
wiley   +1 more source

Central control of body temperature [version 1; referees: 3 approved]

F1000Research, 2016
Central neural circuits orchestrate the behavioral and autonomic repertoire that maintains body temperature during environmental temperature challenges and alters body temperature during the inflammatory response and behavioral states and in response to ...
Shaun F. Morrison
doaj   +1 more source

Accretion discs as regulators of stellar angular momentum evolution in the ONC and Taurus-Auriga [PDF]

, 2014
In light of recent substantial updates to spectral type estimations and newly established intrinsic colours, effective temperatures, and bolometric corrections for pre-main sequence (PMS) stars, we re-address the theory of accretion-disc regulated stellar angular momentum (AM) evolution.
arxiv   +1 more source

Comprehensive rate coefficients for electron collision induced transitions in hydrogen [PDF]

Astrophysical Journal 780:2 (2014), 2013
Energy-changing electron-hydrogen atom collisions are crucial to regulating the energy balance in astrophysical and laboratory plasmas and relevant to the formation of stellar atmospheres, recombination in H-II clouds, primordial recombination, three-body recombination and heating in ultracold and fusion plasmas.
arxiv   +1 more source

Protracted effects of chronic stress on serotonin-dependent thermoregulation [PDF]

, 2015
Chronic stress is known to affect serotonin (5HT) neurotransmission in the brain and to alter body temperature. The body temperature is controlled in part, by the medial preoptic area (mPOA) of the hypothalamus.
Natarajan, Reka, Northrop, Nicole A., Yamamoto, Bryan K.   +2 more
core   +1 more source

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Methods to estimate body temperature and energy expenditure dynamics in fed and fasted laboratory mice:effects of sleep deprivation and light exposure [PDF]

Monitoring body temperature and energy expenditure in freely-moving laboratory mice remains a powerful methodology used widely across a variety of disciplines–including circadian biology, sleep research, metabolic phenotyping, and the study of body ...
Cantley, James, McKillop, Laura E., Peirson, Stuart N., Swoap, Steven J., van der Vinne, Vincent, Vyazovskiy, Vladyslav V., Wilcox, Sian L.   +6 more
core   +2 more sources

Daily regulation of body temperature rhythm in the camel (Camelus dromedarius) exposed to experimental desert conditions

Physiological Reports, 2014
In the present work, we have studied daily rhythmicity of body temperature (Tb) in Arabian camels challenged with daily heat, combined or not with dehydration.
H. Bouâouda, M. Achaâban, M. Ouassat, Mohammed Oukassou, Mohamed Piro, E. Challet, K. El Allali, P. Pévet   +7 more
semanticscholar   +1 more source

Vertical inhibition of p110α/AKT and N‐cadherin enhances treatment efficacy in PIK3CA‐aberrated ovarian cancer cells

Molecular Oncology, EarlyView.
PIK3CA amplification and PIK3CA mutation enhance ovarian tumorigenicity through an activation of AKT, which phosphorylates YAP at Ser127. This Ser127 phosphorylation leads to the retention of YAP in the cytoplasm and triggers RAC1 activity, promoting cell migration. Additionally, AKT activation increases expression of N‐cadherin, which further enhances
Shibo Zhang, Hei Ip Hong, Victor C. Y. Mak, Yuan Zhou, Yiling Lu, Guanglei Zhuang, Lydia W. T. Cheung   +6 more
wiley   +1 more source

A PROBLEMÁTICA DA TEMPERATURA CORPORAL ENQUANTO UM PROCEDIMENTO DE ENFERMAGEM: CONCEITOS E MECANISMOS REGULADORES

Revista da Escola de Enfermagem da USP
O presente estudo mostra a problemática da temperatura corporal enquanto um procedimento de enfermagem. Apresenta conceitos relacionados à temperatura e suas alterações, e descreve duas entidades nosológicas relacionadas com a elevação da temperatura ...
Maria Teresa Cícero Laganá, Ana Cristina Mancussi e Faro, Thelma Leite Araújo   +2 more
doaj   +1 more source