Replication of Boid Inclusion Body Disease-Associated Arenaviruses Is Temperature Sensitive in both Boid and Mammalian Cells [PDF]
ABSTRACT Boid inclusion body disease (BIDB) is a fatal disease of boid snakes, the etiology of which has only recently been revealed following the identification of several novel arenaviruses in diseased snakes. BIBD-associated arenaviruses (BIBDAV) are genetically divergent from the classical Old and New World arenaviruses and ...
Jussi M Hepojoki +2 more
exaly +6 more sources
Identification of Reptarenaviruses, Hartmaniviruses, and a Novel Chuvirus in Captive Native Brazilian Boa Constrictors with Boid Inclusion Body Disease [PDF]
Boid inclusion body disease (BIBD), caused by reptarenavirus infection, affects captive snake populations worldwide, but the reservoir hosts of reptarenaviruses remain unknown. Here, we report the identification of novel reptarenaviruses, hartmaniviruses, and a chuvirus in captive Brazilian boas with BIBD.
Fernando F Argenta +2 more
exaly +7 more sources
Arenavirus Coinfections Are Common in Snakes with Boid Inclusion Body Disease [PDF]
ABSTRACT Recently, novel arenaviruses were found in snakes with boid inclusion body disease (BIBD); these form the new genus Reptarenavirus within the family Arenaviridae . We used next-generation sequencing and de novo sequence assembly to investigate ...
Jussi M Hepojoki, Udo Hetzel, Anja Kipar
exaly +5 more sources
Isolation, Identification, and Characterization of Novel Arenaviruses, the Etiological Agents of Boid Inclusion Body Disease [PDF]
ABSTRACT Boid inclusion body disease (BIBD) is a progressive, usually fatal disease of constrictor snakes, characterized by cytoplasmic inclusion bodies (IB) in a wide range of cell types. To identify the causative agent of the disease, we established cell cultures from BIBD-positive and -negative boa constrictors.
Udo Hetzel, Pasi Laurinmaki, Anja Kipar
exaly +6 more sources
Molecular characterization of a reptarenavirus detected in a Colombian Red-Tailed Boa (Boa constrictor imperator) [PDF]
The global decline in biodiversity is a matter of great concern for members of the class Reptilia. Reptarenaviruses infect snakes, and have been linked to various clinical conditions, such as Boid Inclusion Body Disease (BIBD) in snakes belonging to the ...
Mohamed A. Abouelkhair +2 more
doaj +2 more sources
A subpopulation of arenavirus nucleoprotein localizes to mitochondria [PDF]
Viruses need cells for their replication and, therefore, ways to hijack cellular functions. Mitochondria play fundamental roles within the cell in metabolism, immunity and regulation of homeostasis due to which some viruses aim to alter mitochondrial ...
Francesca Baggio +4 more
doaj +2 more sources
Virtopsy of a gravid Boa constrictor using computed tomography and magnetic resonance imaging [PDF]
: This article presents radiologic examinations of a deeply sedated Boa constrictor with boid inclusion body disease (BIBD) as an adjunction to the subsequent necropsy. This method is known as virtopsy. The Boa constrictor in the present case was gravid.
Dominic Gascho +5 more
doaj +2 more sources
Concussion syndrome is a common disease in neurosurgery, and its incidence ranks first among all traumatic brain injuries. Cognitive dysfunction is one of the most common functional impairments in concussion syndrome. Neuroimaging and content assessments on concussion patients and healthy control subjects are used in this study, which uses MRI ...
Peng Fang +4 more
wiley +2 more sources
Inclusion Body Disease, A Worldwide Infectious Disease of Boid Snakes: A Review
Abstract A disease called inclusion body disease (IBD) is seen worldwide in snakes that are members of the families Boidae and Pythonidae. Snakes affected by this disease often have neurological signs. A diagnosis is based on light microscopic examination of tissues for the presence of intracytoplasmic inclusions that consist of a unique protein ...
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL USA ( host institution ) +2 more
exaly +3 more sources
Generation of Anti-Boa Immunoglobulin Antibodies for Serodiagnostic Applications, and Their Use to Detect Anti-Reptarenavirus Antibodies in Boa Constrictor. [PDF]
Immunoglobulins (Igs), the key effectors of the adaptive immune system, mediate the specific recognition of foreign structures, i.e. antigens. In mammals, IgM production commonly precedes the production of IgG in the response to an infection.
Yegor Korzyukov +4 more
doaj +2 more sources

