Results 41 to 50 of about 70,429 (301)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Frontiers in Earth Science, 2022 With the continuous increase in the mining depth and engineering burying depth, the nonlinear physical and mechanical phenomena exhibited by rock are more complicated.
Feng Chen +3 more
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Góry, Literatura, Kultura, 2021 The first bolts in Poland were fixed in Góry Sokole (Falcon Mountains). This was a climbing technique which became a turning point in rock climbing and changed the ethical framework of mountaineering. The first device for fixing bolts was developed by Tadeusz Zipser, a young mountaineer and graduate of the Wrocław University of Science and Technology ...
openaire +1 more source
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Applied SciencesUpon careful examination, numerous wind turbine collapses can be attributed to the failure of the tower bolts. Nowadays, the Schmidt–Neuper algorithm is extensively accepted in wind turbine tower bolt design.
Mingxing Liu +6 more
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Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Experimental study on corrosion of 3D-printed bolts based on metal powder in simulated mine water
工程科学学报Coal has long been central to China’s energy strategy, with bolt support playing a crucial role in mining operations. As mining depths increase, more challenging conditions emerge, including corrosive underground environments marked by water, high ...
Wei YUN +4 more
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Study on the Lateral Force of the Single Lap Joint of Composite Laminates
Hangkong gongcheng jinzhan, 2018 In the composite material single lap joint structure, due to the eccentricity of the load, the lateral force is generated in the lap joint, which causes the lateral displacement of the joint and deflects the bolt.
Zhang Zhihong, Zhang Boping, Yang Jie
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A block–particle–bar coupled algorithm to simulate tunnel excavation and support
工程科学学报, 2023 During tunnel excavation, the stress of the surrounding rock is redistributed, leading to a local stress concentration around the tunnel. In addition, blasting excavation and other factors lead to a strength reduction of rock mass around the tunnel and ...
Xiao-guang LI, Chang-hong LI, Chun FENG
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Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source