Results 51 to 60 of about 70,429 (301)

Development of simplified finite-element model using interpolation rigid-body element for bolted joint of attachment rail in rolling stock

open access: yesNihon Kikai Gakkai ronbunshu
Since many bolted connections are used in rolling stock, it is necessary to improve the prediction accuracy of stress distribution of the connections in order to reduce the weight and improve the reliability of the structure. In addition, it is important
Ryo UETA   +7 more
doaj   +1 more source

TYPES OF STEEL AND CONCRETE COMPOSITE CABLE SPACE FRAMES

open access: yesNauka ta progres transportu, 2016
Purpose. Modern terms of the construction generate the need to find new structures, including roof systems that would meet modern requirements. An important aspect in finding constructive solutions for new structures is the use of reliable and advanced ...
G. M. Gasii
doaj   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Effect of the Residual Stress on the Fatigue Strength of a Bolt in Bolt/Nut Assemblies

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2012
The residual stress at the thread root of a bolt is one of the major factors influencing the fatigue strength. Some hypotheses have been proposed to predict the fatigue strength from the local stress on the thread root.
Akihiro FURUKAWA   +2 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Experimental analysis of bolts employed as shear connectors in circular concrete-filled tube columns

open access: yesRevista IBRACON de Estruturas e Materiais, 2019
This paper presents experimental and theoretical analysis of bolts employed as shear connectors in circular concrete-filled steel tube columns (CFTs).
E. M. XAVIER   +4 more
doaj   +2 more sources

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Parallel computation method for critical stress of roadway with a combination of bolts and a simplified hydraulic support

open access: yesMeitan kexue jishu
The critical stress is a foundation for evaluating the safety of roadways in rockburst coal mines. Currently, theoretical formulas are widely used to estimate the critical stress, possessing limited applicability.
Xuebin Wang   +4 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

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