Results 121 to 130 of about 5,537 (176)
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Experientia, 1971
Viene riportata la sintesi della piroglutamil-glutaminil-arginil-leucil-glicil-asparaginil-glutaminil-triptofanil-alanil-valil-glicil-istidil-leucil-metioninamide, un peptide identico per proprieta fisiche, chimiche e biologiche alla bombesina.
L, Bernardi +3 more
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Viene riportata la sintesi della piroglutamil-glutaminil-arginil-leucil-glicil-asparaginil-glutaminil-triptofanil-alanil-valil-glicil-istidil-leucil-metioninamide, un peptide identico per proprieta fisiche, chimiche e biologiche alla bombesina.
L, Bernardi +3 more
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Bombesin, bombesin analogs, and related peptides: effects on thermoregulation
Biochemistry, 1978The synthesis and biological evaluation on thermoregulation of 39 peptides related to bombesin (structural analogues or other naturally occurring peptides) are described. The bioassay system reported measures the ability of peptides injected intracisternally to lower body temperature of cold (4 degrees C) exposed rats.
J E, Rivier, M R, Brown
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Bombesin Receptors in the Brain
Annals of the New York Academy of Sciences, 1996We have shown that in the central nervous system BN receptors are closely associated with 5-HT systems. On a subpopulation of dorsal raphe neurons, NMB receptors are able to depolarize cells by reducing gK+. In one of the target regions of the dorsal raphe 5-HT neurons, the SCN, we have also shown that neurons are excited by BN-related peptides. In the
G N, Woodruff +3 more
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World Journal of Surgery, 1979
AbstractThe bombesin (BBS) infusion test was performed in 232 subjects with a variety of conditions, including 35 normal individuals, 41 duodenal ulcer patients, 13 gastric ulcer patients, and 14 patients with Zollinger‐Ellison syndrome. Side effects occurred in 80% of patients, but in only 6% was the test discontinued due to discomfort.
BASSO, Nicola, E. Lezoche, V. Speranza
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AbstractThe bombesin (BBS) infusion test was performed in 232 subjects with a variety of conditions, including 35 normal individuals, 41 duodenal ulcer patients, 13 gastric ulcer patients, and 14 patients with Zollinger‐Ellison syndrome. Side effects occurred in 80% of patients, but in only 6% was the test discontinued due to discomfort.
BASSO, Nicola, E. Lezoche, V. Speranza
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[D-Phe12]bombesin analogues: a new class of bombesin receptor antagonists
American Journal of Physiology-Gastrointestinal and Liver Physiology, 1987Previous attempts to develop analogues of bombesin that function as specific receptor antagonists have been unsuccessful. Alteration of the histidine in luteinizing hormone releasing factor has resulted in analogues that function as competitive antagonists. In the present study we have used a similar strategy and altered the histidine in bombesin.
P, Heinz-Erian +5 more
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A synthetic glycine-extended bombesin analogue interacts with the GRP/bombesin receptor
European Journal of Pharmacology, 2000alpha-amidation of a peptide (which takes place from a glycine-extended precursor) is required to produce biologically active amidated hormones, such as gastrin-releasing peptide (GRP)/Pyr-Gln-Arg-Leu-Gly-Asn-Gln-Trp-Ala-Val-Gly-His-Leu-Met-NH(2) (bombesin).
C, Oiry +8 more
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1983
Several years ago our group reviewed the literature on neuropeptides in the Handbook of Psychopharmacology (Prange et al., 1978). We bring this to the reader’s attention for two reasons. First, although the task was complex, it was accomplished with reasonable comprehensibility in a single article.
Charles B. Nemeroff +2 more
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Several years ago our group reviewed the literature on neuropeptides in the Handbook of Psychopharmacology (Prange et al., 1978). We bring this to the reader’s attention for two reasons. First, although the task was complex, it was accomplished with reasonable comprehensibility in a single article.
Charles B. Nemeroff +2 more
openaire +1 more source
Physiology, 1991
The abrupt cessation of feeding, before useful nutrient absorption, indicates that sensory nerves or gut hormones from the upper alimentary canal signal "preabsorptive satiety." Several neurotransmitters and hormonal substances have been identified as putative satiety agents.
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The abrupt cessation of feeding, before useful nutrient absorption, indicates that sensory nerves or gut hormones from the upper alimentary canal signal "preabsorptive satiety." Several neurotransmitters and hormonal substances have been identified as putative satiety agents.
openaire +1 more source