Results 131 to 140 of about 24,376 (300)

Cracking the Clock: Ronald J. Konopka and Seymour Benzer. [PDF]

Proc Natl Acad Sci U S A, 2021
Hardcastle M.
europepmc   +1 more source

Buena fe subjetiva y buena fe objetiva. Equívocos a los que conduce la falta de claridad en la distinción de tales conceptos [PDF]

El presente escrito tiene por objeto dejar en evidencia la confusión que en cierto sector de la jurisprudencia colombiana existe entre el concepto de buena fe objetiva y el concepto de buena fe subjetiva, que ha trascendido, por demás, a una parte de la ...
Martha Lucía Neme Villarreal
core  

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

Where Does Open Science Lead Us During a Pandemic? A Public Good Argument to Prioritize Rights in the Open Commons. [PDF]

Camb Q Healthc Ethics, 2021
Capps B.
europepmc   +1 more source

A bona fide MAP kinase

Journal of Biological Chemistry, 2022
openaire   +2 more sources

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

,,JURYSPRUDENCJA LWOWSKA’’ OGÓLNOPOLSKA KONFERENCJA NAUKOWA NA WYDZIALE PRAWA I ADMINISTRACJI UNIWERSYTETU IM. ADAMA MICKIEWICZA W POZNANIU. POZNAŃ, 30 MARCA 2012 R. [PDF]

, 2012
Kola, Jarosław, Kruszyńska, Joanna
core   +2 more sources

A logical development: biomedicine's fingerprints are on the instrument of close reading in Charonian Narrative Medicine. [PDF]

Med Humanit, 2022
Neilson S.
europepmc   +1 more source

How do multiple long-term conditions impact on the cost-of-illness in early rheumatoid arthritis? [PDF]

RMD Open, 2022
Hsieh PH, Geue C, Wu O, McIntosh E, Siebert S.   +4 more
europepmc   +1 more source

Outcomes and risk factors of hemorrhage in patients with resected brain metastases

International Journal of Cancer, EarlyView.
What's New? Brain metastases may present with hemorrhage, yet risk factors and clinical outcomes remain unclear. Based on a cohort of 880 patients with resected brain metastases, this study identified tumor volume and primary tumor histology (melanoma and non‐small cell lung cancer) as key predictors of hemorrhage.
Melisa S. Guelen, Kiarash Ferdowssian, Niklas Jung, Hava N. Celik, Andrea Dell'Orco, Semil Eminovic, Anton Früh, Majd Samman, Güliz Acker, Arend Koch, Helena Radbruch, Michael Scheel, Mike P. Wattjes, Julia Onken, Peter Vajkoczy, Nils Hecht, Jawed Nawabi, David Wasilewski   +17 more
wiley   +1 more source