Results 61 to 70 of about 24,397 (302)
Advanced Science, EarlyView.SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding +10 more
wiley +1 more source
The role of public policy reservation in international contracts [PDF]
Zbornik Radova: Pravni Fakultet u Novom Sadu, 2018 Among the main roles of public policy in the field of international contracts is its role of the object of protection of the public policy reservation, one of the most important tools of private international law, which enables the forum to refuse ...
Ristić Bojana D.
doaj
Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis
Advanced Science, EarlyView.This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen +7 more
wiley +1 more source
Shakespeare in the Head for Health: A Reality Orientation Option for Alzheimer’s Worriers
Nonpartisan Education Review, 2009 By way of bona fides: As with many Americans, my own extended family has over the years given me plenty of direct contact with senile dementia, the general label for Alzheimer’s disease.
Robert Oliphant
doaj
Carter v Boehm: facts and context [PDF]
, 2016 There is a curious irony in the lawsuit Carter v Boehm. The final decision of the Court of King’s Bench, delivered by Chief Justice Mansfield at Easter 1766, famously articulated the principle of uberrima fides (utmost good faith), which became the ...
Pearson, Robin
core
Advanced Science, EarlyView.This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun +19 more
wiley +1 more source
Relevant norms of Roman law in Russian civil legislation
Russian Studies in Law and PoliticsBackground. The article examines the impact of Roman Law principles on contemporary Russian civil legislation. The authors analyze key legal institutions, such as principle of bona fides, easements (servitutes), contractural obligations (pacta sunt ...
Mikhail Y. Ushakov, Oleg A. Mekka
doaj +1 more source
The exercise and protection of the right to a surviror's pension in extramarital relations, or what has the legislator failed to disclose? [PDF]
Zbornik Radova Pravnog Fakulteta u Nišu, 2022 The amendments to the Pension and Disability Insurance Act, enacted at the end of 2019, envisage that the right to a family pension can also be exercised by the surviving extramarital partner.
Obradović Goran, Tasić Anđelija
doaj
Advanced Science, EarlyView.Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang +3 more
wiley +1 more source
Trust Strategies for the Semantic Web [PDF]
, 2004 Everyone agrees on the importance of enabling trust on the SemanticWebto ensure more efficient agent interaction. Current research on trust seems to focus on developing computational models, semantic representations, inference techniques, etc.
Alani, Harith +3 more
core +1 more source