Results 61 to 70 of about 1,371 (289)

Bona Fides в налоговом праве России: мы идем своим путем

Сибирское юридическое обозрение, 2010
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doaj  

Hierarchia społeczna i categorie prave. Fides i bona fides

, 2015
It is a common misconception that fides and bona fides are ethical principles with changeable content, shaped by the development of social and moral values.
FIORI, ROBERTO, Fiori, R
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TSPYL5 Promotes Triple‐Negative Breast Cancer Metastasis by Antagonizing USP10‐Mediated PTEN Stabilization to Unleash a ZEB1‐Dependent EMT Program

Advanced Science, EarlyView.
The hyperactivation of PI3K/AKT signaling in PTEN wild‐type triple‐negative breast cancer represents a clinical paradox. We delineate a novel post‐translational regulatory axis wherein the oncogene TSPYL5 competitively antagonizes the deubiquitinase USP10.
Jiaying Shi, Ming Yi, Shengyu Xie, Zhaokun Wang, Xinyue Zhang, Yangwei Zhang, Rui Tang, Yuan Yang, Yunqiang Liu   +8 more
wiley   +1 more source

TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk

Hepatology, EarlyView., 2022
The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam, Jianqing Yu, Hao Huang, Xiaofan Ding, Alissa M. Wong, Howard H. Leung, Anthony W. Chan, Kelvin K. Ng, Mingjing Xu, Xin Wang, Nathalie Wong   +10 more
wiley   +1 more source

UCHL3 Regulates Subgenomic Flaviviral RNA Condensates to Promote Virus Propagation

Advanced Science, EarlyView.
ABSTRACT Flavivirus subgenomic RNAs (sfRNAs) antagonise antiviral defences, yet how sfRNAs are organized and maintained in cells remains poorly understood. Here we identify ubiquitin C‐terminal hydrolase L3 (UCHL3) as a post‐translational regulator of flavivirus sfRNA stability and function.
Oscar Trejo‐Cerro, Anna Beekmayer‐Dhillon, Qi Wen Teo, Lewis Siu, Ming Yuan Li, Kate J. Heesom, Adán Pinto‐Fernández, Sumana Sanyal   +7 more
wiley   +1 more source

Epithelial TRIM27 Inhibits Intestinal Inflammation in Ulcerative Colitis by the USP7/TRIM27‐IKK Double Negative‐Feedback

Advanced Science, EarlyView.
ABSTRACT The E3 ubiquitin ligase tripartite motif 27 (TRIM27) is a negative regulator of NF‐κB activation and the innate immune response, and TRIM27 deficiency significantly impairs dextran sulfate sodium (DSS)‐induced colitis. The function of TRIM27 in intestinal epithelial cells (IECs), the mechanism by which TRIM27 inhibits the NF‐κB pathway and its
Weimin Xu, Zhebin Hua, Zhujiang Dai, Shasha Zhang, Yihan Jiang, Wensong Ge, YingWei Chen, Zhongchuan Wang, Bing Zhang, Chen‐Ying Liu, Peng Du   +10 more
wiley   +1 more source

Shakespeare in the Head for Health: A Reality Orientation Option for Alzheimer’s Worriers

Nonpartisan Education Review, 2009
By way of bona fides: As with many Americans, my own extended family has over the years given me plenty of direct contact with senile dementia, the general label for Alzheimer’s disease.
Robert Oliphant
doaj  

The role of public policy reservation in international contracts [PDF]

Zbornik Radova: Pravni Fakultet u Novom Sadu, 2018
Among the main roles of public policy in the field of international contracts is its role of the object of protection of the public policy reservation, one of the most important tools of private international law, which enables the forum to refuse ...
Ristić Bojana D.
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Harmonising Legal Values and uBuntu: The Quest for Social Justice in the South African Common Law of Contract

Potchefstroom Electronic Law Journal, 2019
In this article, a comparison is drawn between the role of good faith in the development of the Roman law of contract and the emerging role of ubuntu in the South African common law of contract.
Hanri Magdalena Du Plessis
doaj   +1 more source

A ESSÊNCIA DA BONA FIDES E SUA RELAÇÃO COM A TEORIA DO ERRO / THE ESSENCE OF BONA FIDES AND ITS RELATION TO THE THEORY OF ERROR

, 2011
DOI: http://dx.doi.org/10.12957/rqi.2011.10186Trabalho recebido e avaliado pelo Conselho executivo da Revista Quaestio IurisResumo O presente trabalho analisa a teoria romana da bona fides e sua relação com a teoria do erro, um artigo de Pietro ...
Bonfante, Pietro
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