Results 91 to 100 of about 23,675,183 (257)
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Clusters and case vignettes of impaired maternal–fetal bonding in pregnancy: A mixed method approach
PCN ReportsAim Clinical attention to and understanding of women with impaired fetal bonding is important for early therapeutic intervention. This study aimed to clarify the clinical characteristics of women belonging to groups derived by cluster analysis of ...
Toshinori Kitamura +3 more
doaj +1 more source
Fracture of Ag sintering bonding interface on active metal brazing substrates for power electronics
Results in Surfaces and InterfacesThis study investigated the effects of Cu and Ag surface treatments on active metal brazing (AMB) substrates from two manufacturers (A and B) with respect to the sintered bonding characteristics of Ag paste and film.
Jeeyeon Park +5 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
STUDY ON THE FORMATION MECHANISM OF BONDING LAYER AROUND PILE BODY IN SOFT CLAY
Civil Engineering Journal, 2019 After jacked pile is driven into the soft clay,a bonding layer would form a around pile body,it enlarges the pile side area and increases its bearing capacityeffectively.
Jiang Yue-Nan, Chen Song
doaj +1 more source
Spectroscopy of halogen bonding in solution
, 2021 : In order to observe halogen bonding in solution and thus gain a better understanding of it, one must apply spectroscopic techniques. These may be used separately or in conjunction with one another and consist mainly of IR and Raman vibrational ...
Scott Wilcox +8 more
core +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Energy provisions in bonding bill
, 2012 "April 18, 2012."; Summarizes the energy-related provisions of the governor's bonding bill (sSB 25), favorably reported by the Finance, Revenue and Bonding Committee.; Harvested from the web on 4/23 ...
Pinho, Rute.
core +1 more source