Results 101 to 110 of about 23,675,183 (257)
Micro and Nano Engineering, 2019 The hybrid bonding technique, used for the bonding of metal-electrode and insulator hybrid interfaces with a high alignment accuracy, is very important for the three-dimensional integration technology.
Jun Utsumi, Kensuke Ide, Yuko Ichiyanagi
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Plasma-activated direct bonding of coated optical glasses
, 2022 S.71For spectrometric applications in space the benefits of direct bonding are highly promising. However, direct bonding of optical coatings is still challenging.
Rothhardt, C. +8 more
core +1 more source
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Thin bonding wires temperature measurement using optical fiber sensors [PDF]
, 2011 In this work we demonstrate the use of optical fiber sensors to measure temperature in thin metallic bonding wires. Temperature was measured in copper wires with diameter of 0.10, 0.28, 0.60 and 0.70 mm and for different values of the driven electrical ...
P. Antunes +14 more
core +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Temporary wafer bonding by polyelectrolyte interlayers
, 2022 S.179-186Polyelectrolyte multilayers of just a few nanometers thickness were used for direct bonding of silicon, thermally oxidized silicon, and borosilicate wafers, respectively, and the bonded wafer pairs were characterized during and after annealing ...
Klages, C.-P. +4 more
core +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Low temperature bonding of hetero-materials using ambient pressure plasma activation
, 2022 S.73-74One critical parameter in wafer level bonding is the process temperature. It should be kept as low as possible. Therefore the reasons are low-melting materials used for vias and different coefficients of thermal expansion (CTE) of bonding partners.
Wünsch, D. +5 more
core +1 more source
How to make head or tail of bridging and bonding? Adressing the methodological ambiguity [PDF]
A distinction has recently been proposed between bridging (or encompassing) and bonding (or inward-looking) social networks. However, existing theoretical contributions remain vague as to the fundamental meaning of both concepts.
Geys, Benny
core