Results 101 to 110 of about 22,611,724 (309)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Bonding and correlation analysis of various SiCO isomers

open access: yes, 2002
The structural properties for various SiCO isomers in the singlet and triplet states have been investigated using CASSCF methods with a 6-311 +G* basis set and also using three DFT and MP2 with same basis set for those systems except for the linear ...
Bu, YX, Han, KL
core   +1 more source

Congregational bonding social capital and psychological type : an empirical enquiry among Australian churchgoers [PDF]

open access: yes, 2012
This study explores the variation in levels of bonding social capital experienced by individual churchgoers, drawing on data generated by the Australian National Church Life Survey, and employing a five-item measure of church-related bonding social ...
Robbins, Mandy   +2 more
core   +1 more source

(Invited) Glass-Glass Direct Bonding

open access: yes, 2022
S.3-11Glass-glass direct bonding is closely rated to proven processes in Si-Si wafer bonding. We describe plasma-assisted hydrophilic direct bonding of different glass materials for various applications in optical and high precision engineering ...
Zeitner, Uwe   +5 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

The Body as a Therapeutic Tool: Validating the Effectiveness of Bonding Psychotherapy [PDF]

open access: yes, 2023
openLa Bonding Psychotherapy è un approccio basato sulle emozioni e sul contatto con l'altro che si è visto essere terapeutico. L'approccio è utilizzato in molti stati non Italiani e l'obiettivo di questo elaborato è proprio quello di validare ...
MOCCIA, TERESA GRAZIA
core  

Plasma-activated direct bonding of coated optical glasses

open access: yes, 2022
S.71For spectrometric applications in space the benefits of direct bonding are highly promising. However, direct bonding of optical coatings is still challenging.
Rothhardt, C.   +8 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Development of nonuniform residual stresses during anodic bonding

open access: yes, 2022
S.553-562Nonuniform residual stresses may develop during anodic bonding due to variations in wafer curvature prior to bonding or due to nanotopography interactions between the bonding surfaces.
Gerbach, R.   +5 more
core   +1 more source

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