Results 91 to 100 of about 6,066,361 (406)

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

open access: yesMolecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva   +5 more
wiley   +1 more source

Milieu Models and Milieu Instruments in Market Research

open access: yesForum: Qualitative Social Research, 2004
In the case of social milieu research, the practical, non-scientific context of market research can create problems for practical social research. Some of these problems are examined in this paper.
Rainer Diaz-Bone
doaj  

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Injectable hydrogels for cartilage and bone tissue engineering

open access: yesBone Research, 2017
Tissue engineering has become a promising strategy for repairing damaged cartilage and bone tissue. Among the scaffolds for tissue-engineering applications, injectable hydrogels have demonstrated great potential for use as three-dimensional cell culture ...
Mei Liu   +8 more
semanticscholar   +1 more source

Bone metastases

open access: yesNature Reviews Disease Primers, 2020
Bone is the most frequent site for metastasis for many cancers, notably for tumours originating in the breast and the prostate. Tumour cells can escape from the primary tumour site and colonize the bone microenvironment. Within the bone, these disseminated tumour cells, as well as those arising in the context of multiple myeloma, may assume a state of ...
Robert E Coleman   +9 more
openaire   +4 more sources

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Review Essay: Situational Analysis—Strauss Meets Foucault?

open access: yesForum: Qualitative Social Research, 2012
With the (German translation) of the volume "Situational Analysis" by Adele CLARKE, a new approach to the development of Grounded Theory Methodology (GTM) is presented. CLARKE radicalizes the methodological standpoint of classical pragmatism.
Rainer Diaz-Bone
doaj  

The Myths and Beliefs Surrounding Mappaenre Bunge: Disease, Tradition, and Social Impact in Bugis Society

open access: yesJurnal Antropologi: Isu-Isu Sosial Budaya
The Mappaenre Bunge tradition as a ritual that has been going on for generations has deep meaning for the Bugis people. The community believes that by carrying out this tradition, they will establish a harmonious relationship with their ancestors and the
Mutmainna Mutmainna   +6 more
doaj   +1 more source

Porcine bone scaffolds adsorb growth factors secreted by MSCs and improve bone tissue repair [PDF]

open access: yes, 2017
An ideal tissue-engineered bone graft should have both excellent pro-osteogenesis and pro-angiogenesis properties to rapidly realize the bone regeneration in vivo . To meet this goal, in this work a porcine bone scaffold was successfully used as a Trojan
Bressan, Eriberto   +6 more
core   +2 more sources

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

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