Results 101 to 110 of about 10,064,619 (345)

Navigating Pubertal Goldilocks: The Optimal Pace for Hierarchical Brain Organization

open access: yesAdvanced Science
Adolescence is a timed process with an onset, tempo, and duration. Nevertheless, the temporal dimension, especially the pace of maturation, remains an insufficiently studied aspect of developmental progression.
Hanna Szakács   +7 more
doaj   +1 more source

Efficacy of first-year GnRHa therapy in girls with idiopathic central precocious puberty diagnosed after age 8: a retrospective study

open access: yesGynecological Endocrinology
Purpose This study aimed to evaluate the short-term benefits of GnRHa therapy, with a specific focus on the first year of treatment, in girls diagnosed with idiopathic central precocious puberty (ICPP) after age 8, providing essential evidence to inform ...
Ming-ming Ni   +6 more
doaj   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

open access: yesFEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu   +9 more
wiley   +1 more source

Characterization of ribosome heterogeneity during endothelial to hematopoietic transition

open access: yesFEBS Open Bio, EarlyView.
The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian   +4 more
wiley   +1 more source

High LRIG1 expression predicts lymph node metastasis in patients with uterine cervical cancer

open access: yesFEBS Open Bio, EarlyView.
Lymph node status is crucial in determining treatment for women with early‐stage cervical cancer. We demonstrate that high LRIG1 protein expression in primary tumors can predict lymph node metastases. Our findings support further investigation of LRIG1 as a biomarker to improve staging accuracy and guide treatment decisions in cervical cancer patients.
Pernilla Israelsson   +5 more
wiley   +1 more source

Reliability of Two Recently Developed Procedures Assessing Biological Maturity by Ultrasound Imaging—A Pilot Study

open access: yesChildren
During puberty, the biological maturity of children of the same chronological age differs. To generate equal opportunities for talent selection in youth sports, the athlete’s biological maturity should be considered.
Nicole Hutmacher   +4 more
doaj   +1 more source

Age of the Oldoway Bone Beds, Tanganyika Territory [PDF]

open access: bronze, 1931
L. S. B. Leakey   +2 more
openalex   +1 more source

Determinants of Advanced Bone Age in Childhood Obesity


open access: yesHormone Research in Paediatrics, 2017
Background: Childhood obesity is associated with advanced bone age (BA). Previous studies suggest that androgens, oestrogens, sex hormone-binding globulin, and insulin are responsible for this phenomenon, but results are contradictory and might be biased
C. J. de Groot   +6 more
semanticscholar   +1 more source

NMDAR‐Antibody Encephalitis Diagnosed With Primary Central Nervous System Lymphoma: A Case Series

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT N‐methyl‐D‐aspartate receptor‐antibody encephalitis (NMDAR encephalitis) is one of the most common forms of autoimmune encephalitis, with a paraneoplastic relationship described in approximately 38%. Primary central nervous system lymphoma (PCNSL) is a rare hematologic malignancy that is not often considered as the underlying neoplasm in this ...
Soo Hyun Ahn   +4 more
wiley   +1 more source

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