Results 101 to 110 of about 1,877,704 (275)

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

Brain Pathology, Volume 36, Issue 4, July 2026.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga, Eva Fernández‐Muñoz, Jorge M. Charco, Enric Vidal, Diego Herrero‐Martínez, Josu Galarza‐Ahumada, Cristina Sampedro‐Torres‐Quevedo, Samanta Giler, Mariví Geijo, Gloria González‐Aseguinolaza, Hasier Eraña, Joaquín Castilla   +11 more
wiley   +1 more source

Bone Densitometry in Clinical Practice Application and Interpretation

, 2004
Drawing on the proven qualities of her highly regarded first edition of Bone Densitometry in Clinical Practice: Application and Interpretation, Sydney Lou Bonnick, MD, has thoroughly updated and dramatically expanded this new edition so that family ...
Bonnick, Sydney Lou
core   +1 more source

Estudo da correlação da densitometria óssea e do perímetro diafisário medial do terceiro metacarpiano em equinos

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2012
In this study, 14 "post mortem" equine metacarpal bones were evaluated to correlate the medial III metacarpus perimeter to dorsal bone density of the same region using Computed Tomography and Quantitative Ultrasound (QUS).
A.C.S. Aguiar, V.M.V. Machado, R.V. Santos, J.N.P. Puoli Filho, M.D.S. Mota, L.C. Vulcano   +5 more
doaj   +1 more source

Parasports for cerebral palsy: Thinking and ‘prescribing’ beyond the Paralympics

Developmental Medicine &Child Neurology, Volume 68, Issue 7, Page 896-902, July 2026.
This narrative review synthesizes current evidence on parasport participation for individuals with cerebral palsy, highlighting key benefits, and providing sport‐specific adaptations that enhance accessibility of parasport. Abstract The landscape of care for individuals with cerebral palsy (CP) has evolved far beyond ‘fixing’ impairments toward a life ...
Julia E. Hanes, Joel J. Ewert, Amalie Holmsen‐Wong, Peter Rosenbaum, Ram Mishaal, Dynai Eilig   +5 more
wiley   +1 more source

Serum Dickkopf-1 Level in Postmenopausal Females: Correlation with Bone Mineral Density and Serum Biochemical Markers

Journal of Osteoporosis, 2013
Objective. To assess serum level of Dickkopf-1 in postmenopausal females and its correlation with bone mineral density and serum biochemical markers. Methods. Bone densitometry, serum Dickkopf-1, calcium, phosphorus, and alkaline phosphatase were done in
Sahar Fathi Ahmed, Neveen Fouda, Amal Ahmed Abbas   +2 more
doaj   +1 more source

Comparison of Repetition‐Based Progressive‐Overload Strategies in Resistance Training: Rest‐Pause Versus Drop Sets

Scandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 7, July 2026.
ABSTRACT Rest‐pause (RP) and drop sets (DS) are widely used as intensification strategies during resistance training. However, their incorporation within a repetition‐based progressive‐overload (PO) model and their effects under supervised conditions are not well established. We compared progressive‐overload rest‐pause (PO‐RP) with progressive‐overload
Salvador Vargas‐Molina, Alejandro García‐Palumbo, Jorge L. Petro, Diego A. Bonilla, Manuel García‐Sillero, Leandro Carbone, Brad J. Schoenfeld, Javier Benítez‐Porres   +7 more
wiley   +1 more source

Targeting Fatty Acid Synthase With Berberine Promotes IL‐10 Production in Macrophages and Prevents Relapse in a Murine Colitis Model

The FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Berberine enhances IL‐10 production in macrophages via FASN‐dependent mechanisms, thereby promoting epithelial repair and preventing colitis relapse. Created with BioRender.com. ABSTRACT Inflammatory bowel disease (IBD) is a chronic inflammatory disorder characterized by alternating periods of remission and relapse.
Shusaku Hayashi, Yudai Ogawa, Nonoka Wakabayashi, Koga Tokuyama, Makito Oku, Takeshi Yamamoto, Shinichi Kato, Asma Nusrat, Makoto Kadowaki   +8 more
wiley   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, Volume 7, Issue 2, Page 35-51, June 2026.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Evolution of bone densitometry parameters and risk of fracture in coeliac disease: a 10-year perspective. [PDF]

Intern Emerg Med, 2023
Tovoli F, Pallotta DP, Giamperoli A, Zavatta G, Skoracka K, Raiteri A, Faggiano C, Krela-Kaźmierczak I, Granito A.   +8 more
europepmc   +1 more source

Hepatocyte PIEZO1 Negatively Regulates Lipogenesis and Ameliorates MASLD by Sensing Membrane Tension and Activating AMPK

Advanced Science, Volume 13, Issue 34, 19 June 2026.
Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen, Qimeng Wang, Ke Yang, Qinghai Lian, Xuyun Peng, Zhiyong Gong, Xinyi Zhao, Yong Wu, Tian Tao, Siqi Xu, Yifan Chen, Xiaoyan Tang, Jinghui Guo, Geyang Xu, Qi Zhang   +14 more
wiley   +1 more source