Results 1 to 10 of about 1,053,788 (184)
Ferroptosis and Its Potential Role in Metabolic Diseases: A Curse or Revitalization?
Frontiers in Cell and Developmental Biology, 2021 Ferroptosis is classified as an iron-dependent form of regulated cell death (RCD) attributed to the accumulation of lipid hydroperoxides and redox imbalance.
Jia-Yue Duan +13 more
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Genetics and Epigenetics of Bone Remodeling and Metabolic Bone Diseases
International Journal of Molecular Sciences, 2022 Bone metabolism consists of a balance between bone formation and bone resorption, which is mediated by osteoblast and osteoclast activity, respectively.
L. Otòn-Gonzalez +9 more
semanticscholar +1 more source
Hereditary Metabolic Bone Diseases: A Review of Pathogenesis, Diagnosis and Management
Genes, 2022 Hereditary metabolic bone diseases are characterized by genetic abnormalities in skeletal homeostasis and encompass one of the most diverse groups among rare diseases.
N. Charoenngam +3 more
semanticscholar +1 more source
Metabolic Bone Diseases and New Drug Developments
Biomolecules & Therapeutics, 2022 Metabolic bone diseases are serious health issues worldwide, since several million individuals over the age of 50 are at risk of bone damage and should be worried about their bone health. One in every two women and one in every four men will break a bone
V. Natesan, Sung-jin Kim
semanticscholar +1 more source
The Multi-Therapeutic Role of MSCs in Diabetic Nephropathy
Frontiers in Endocrinology, 2021 Diabetic nephropathy (DN) is one of the most common diabetes mellitus (DM) microvascular complications, which always ends with end-stage renal disease (ESRD).
Yi Wang +10 more
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Secondary Osteoporosis and Metabolic Bone Diseases
Journal of Clinical Medicine, 2022 Fragility fracture is a worldwide problem and a main cause of disability and impaired quality of life. It is primarily caused by osteoporosis, characterized by impaired bone quantity and or quality.
M. Sobh +7 more
semanticscholar +1 more source
BMC Pediatrics, 2022 Background Osteogenesis imperfecta (OI) causes a number of abnormalities in somatic development. The predominant symptoms are reduced bone mass and an increased risk of fractures as well as bone deformities and short stature.
E. Jakubowska-Pietkiewicz +4 more
doaj +1 more source
Biomedicines, 2021 Endothelial progenitor cells (EPC), which are key effectors in the physiologic vascular network, have been described as relevant players in autoimmune diseases.
Verónica Pulito-Cueto +15 more
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Lack of association of vitamin D receptor BsmI gene polymorphism with bone mineral density in Spanish postmenopausal women [PDF]
PeerJ, 2015 Osteoporosis is a polygenic disorder that is determined by the effects of several genes, each with relatively modest effects on bone mass. The aim of this study was to determine whether the vitamin D receptor single nucleotide polymorphism BsmI is ...
Jose M. Moran +6 more
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Cells, 2022 In the physiological condition, the skeletal system’s bone resorption and formation are in dynamic balance, called bone homeostasis. However, bone homeostasis is destroyed under pathological conditions, leading to the occurrence of bone metabolism ...
Wei Chen +5 more
semanticscholar +1 more source