Results 1 to 10 of about 441,833 (304)
The Multi-Therapeutic Role of MSCs in Diabetic Nephropathy
Frontiers in Endocrinology, 2021 Diabetic nephropathy (DN) is one of the most common diabetes mellitus (DM) microvascular complications, which always ends with end-stage renal disease (ESRD).
Yi Wang +10 more
doaj +1 more source
BMC Pediatrics, 2022 Background Osteogenesis imperfecta (OI) causes a number of abnormalities in somatic development. The predominant symptoms are reduced bone mass and an increased risk of fractures as well as bone deformities and short stature.
E. Jakubowska-Pietkiewicz +4 more
doaj +1 more source
Biomedicines, 2021 Endothelial progenitor cells (EPC), which are key effectors in the physiologic vascular network, have been described as relevant players in autoimmune diseases.
Verónica Pulito-Cueto +15 more
doaj +1 more source
Lack of association of vitamin D receptor BsmI gene polymorphism with bone mineral density in Spanish postmenopausal women [PDF]
PeerJ, 2015 Osteoporosis is a polygenic disorder that is determined by the effects of several genes, each with relatively modest effects on bone mass. The aim of this study was to determine whether the vitamin D receptor single nucleotide polymorphism BsmI is ...
Jose M. Moran +6 more
doaj +2 more sources
Biomedicines, 2022 (1) Background: We explored, for the first time, the contribution of angiogenic T cells (TAng) in interstitial lung disease associated to autoimmune disease (AD-ILD+) as potential biomarkers of the disease, evaluating their role in the underlying ...
Verónica Pulito-Cueto +15 more
doaj +1 more source
European Journal of Investigation in Health, Psychology and Education, 2022 (1) Background: During the COVID-19 lockdown, high rates of physical inactivity and dietary imbalances were reported in both adults and adolescents.
Cristina Acedo +10 more
doaj +1 more source
The Controversial Role of Irisin in Clinical Management of Coronary Heart Disease
Frontiers in Endocrinology, 2021 Irisin, a PGC1α-dependent myokine, was once believed to have beneficial effects induced by exercise. Since its first discovery of adipose browning in 2012, multiple studies have been trying to explore the metabolic functions of irisin, such as glucose ...
Wen-Lu Ou-Yang +10 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Long non-coding RNAs (lncRNAs) have emerged as integral regulators of pathophysiological processes, but their specific roles and mechanisms in adipose tissue development remain largely unknown. Here, through microarray analysis, co-expression, and tissue
Fen Xiao +7 more
doaj +1 more source
Gadolinium tagged osteoprotegerin-mimicking peptide: a novel magnetic resonance imaging biospecific contrast agent for the inhibition of osteoclastogenesis and osteoclast activity [PDF]
, 2018 The control of osteoblast/osteoclast cross-talk is crucial in the bone remodelling process and provides a target mechanism in the development of drugs for bone metabolic diseases.
Busquets, Rosa +5 more
core +6 more sources
Type 2 diabetes affects bone cells precursors and bone turnover
BMC Endocrine Disorders, 2018 Background Here we study the effect of type 2 diabetes (T2DM) on bone cell precursors, turnover and cytokines involved in the control of bone cell formation and activity. Methods We enrolled in the study 21 T2DM women and 21 non diabetic controls matched
Francesca Sassi +12 more
doaj +1 more source