Non-alcoholic fatty liver disease connections with fat-free tissues: A focus on bone and skeletal muscle [PDF]
, 2017 The estimates of global incidence and prevalence of non-alcoholic fatty liver disease (NAFLD) are worrisome, due to the parallel burden of obesity and its metabolic complications. Indeed, excess adiposity and insulin resistance represent two of the major
Chiesa, Claudio +4 more
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A novel model to explain dietary factors affecting hypocalcaemia in dairy cattle [PDF]
, 2011 Most dairy cows exhibit different degrees of hypocalcaemia around calving because the gestational Ca requirements shift to the disproportionately high Ca requirements of lactation.
Martin-Tereso Lopez, J. +1 more
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Zoledronic acid and atorvastatin inhibit αvβ3-mediated adhesion of breast cancer cells
Journal of Bone Oncology, 2014 Bone metastases represent common long term complications of patients with breast cancer. Zoledronic acid, an amino-bisphosphonate and mevalonate pathway inhibitor, is an established agent for the treatment of bone metastases.
Maria Wilke +8 more
doaj +1 more source
Gaucher disease: the role of the specialist on metabolic bone diseases.
CLINICAL CASES IN MINERAL AND BONE METABOLISM, 2015 According to European legislation, a disease can be considered rare or "orphan" when it affects less than 1 subject of 2000 (1). Often these diseases affecting the pediatric age, are complex diseases and chronically debilitating and for this motive need ...
L. Masi, M. Brandi
semanticscholar +1 more source
The Role of Autophagy and Mitophagy in Bone Metabolic Disorders
International Journal on Biological Sciences, 2020 Bone metabolic disorders include osteolysis, osteoporosis, osteoarthritis and rheumatoid arthritis. Osteoblasts and osteoclasts are two major types of cells in bone constituting homeostasis.
Shuai Wang +8 more
semanticscholar +1 more source
Vitamin D3 supplementation of a high fat high sugar diet ameliorates prediabetic phenotype in female LDLR–/–and LDLR+/+mice [PDF]
, 2017 © 2017 The Authors. Immunity, Inflammation and Disease Published by John Wiley & Sons Ltd. INTRODUCTION: Fatty liver disease is prevalent in populations with high caloric intake.
Asai +50 more
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Exosomes as Mediators of Cell-to-Cell Communication in Thyroid Disease
International Journal of Endocrinology, 2020 Exosomes are a type of extracellular vehicle, formed by budding cell membranes, containing proteins, DNA, and RNA. Concentrated cargoes from parent cells are enveloped in exosomes, which are cell specific and may have functions in the recipient cell ...
Yi Wang +7 more
doaj +1 more source
Short- and long-term effects of a multi-component physical activity intervention in primary school [PDF]
, 2012 There is compelling evidence that physical activity has numerous health benefits during childhood and adolescence. Insufficient levels of physical activity on the other hand can consequently affect cardiovascular and bone health, which may result in ...
Meyer, Ursina
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Exosomes and Obesity-Related Insulin Resistance
Frontiers in Cell and Developmental Biology, 2021 Exosomes are extracellular vesicles, delivering signal molecules from donor cells to recipient cells. The cargo of exosomes, including proteins, DNA and RNA, can target the recipient tissues and organs, which have an important role in disease development.
Li-Min Lei +9 more
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Primer on the metabolic bone diseases and disorders of mineral metabolism
The Indian journal of medical research, 1994 Part 1 Anatomy and biology of bone matrix and cellular elements: anatomy and ultrastructure of bone bone morphogenesis and embryologic development bone formation - osteoblast lineage cells, growth factors, matrix proteins and the mineralization process ...
R. Goswami
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