The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
BONE HEALING IN MICE: DOES IT FOLLOW GENERIC MECHANO-REGULATION RULES?
Facta Universitatis. Series: Mechanical Engineering, 2015 Mechanical signals are known to influence bone healing progression. Previous studies have postulated inter-species differences in the mechanical regulation of the bone healing process.
Edoardo Borgiani +3 more
doaj
Short-term Osteoclastic Activity Induced by Locally High Concentrations of Recombinant Human Bone Morphogenetic Protein–2 in a Cancellous Bone Environment [PDF]
, 2009 Study Design. An experimental study investigating osteoclastic activity induced by rhBMP-2 in sheep. Objective. To examine the effects of increasing local rhBMP-2 concentration on osteoclastic response and peri-implant bone resorption.
Badura, Jeffrey +5 more
core +1 more source
Biomimetic implant surface functionalization with liquid L-PRF products: in vitro study [PDF]
, 2018 Objective: Platelet-rich fibrin (PRF) clots and membranes are autologous blood concentrates widely used in oral surgical procedures; less is known, however, about the liquid formulations of such products.
BOZZUTO, GIUSEPPINA +5 more
core +2 more sources
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
The Effect of Oral Isotretinoin on Bone Healing in Rabbit Rhinoplasty Model: An Experimental Study
İstanbul Medical Journal, 2019 Introduction:Since the age at which rhinoplasty is frequently performed is also the age at which acne is frequently seen, a person may be a candidate for both this surgery and isotretinoin therapy.
Şahin Öğreden +2 more
doaj +1 more source
Bone Healing in Femoral Fracture of White Rat with Intramedullary Wire Fixation and Additional Medullary Bone Marrow [PDF]
, 2012 Introduction.Fracture treatment and bone healing is a complicated process and interesting topic. There are a lot of researches in this matter until now.
Antariksa, I. M. (I)
core
Three-dimensional cephalometric evaluation of maxillary growth following in utero repair of cleft lip and alveolar-like defects in the mid-gestational sheep model [PDF]
, 2006 Objective: To evaluate maxillary growth following in utero repair of surgically created cleft lip and alveolar (CLA)-like defects by means of three-dimensional (3D) computer tomographic (CT) cephalometric analysis in the mid-gestational sheep model ...
Adzick NS +45 more
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
The Effects of Bone Chips Dehydrated with Solvent on Healing Bone Defects
Journal of International Medical Research, 2002 The effect of bone chips dehydrated with solvent on the healing of bone defects was evaluated. Solvent-dehydrated spongiose bone chips were placed in experimentally formed cavities in the right back tibia of rabbits.
E Dayi, M Aslan, G Şimşek, AB Yilmaz
doaj +1 more source