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[Bone remodeling and mineral homeostasis].
Clinical calcium, 2006The discovery of receptor activator of nuclear factor-kappaB ligand (RANKL) elucidates the mechanism of osteoclast differentiation and function regulated by osteoblasts. Osteoprotegerin (OPG), a soluble decoy receptor of RANKL, inhibits both differentiation and function of osteoclasts. OPG-deficient (OPG-/-) mice exhibited severe osteoporosis caused by
Midori, Nakamura +2 more
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[Regulation of bone homeostasis by bone cells].
Clinical calcium, 2013Bone is constantly renewed by the balanced action of osteoblastic bone formation and osteoclastic bone resorption both of which mainly occur at the bone surface. This restructuring process called "bone remodeling" is important not only for normal bone mass and strength, but also for mineral homeostasis.
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Bone and plasma calcium homeostasis.
Bone, 1988Regulation of plasma free calcium concentration displays the following features: (1) The level in an individual varies within fairly narrow limits and is characterized by a mean (an estimate of the individual set point) and a standard deviation (an estimate of oscillation about the set point).
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Novel approaches to target the microenvironment of bone metastasis
Nature Reviews Clinical Oncology, 2021Lorenz C Hofbauer +2 more
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Hypercalcemia and cancer: Differential diagnosis and treatment
Ca-A Cancer Journal for Clinicians, 2018Sarah B Fisher
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Mechanisms of bone development and repair
Nature Reviews Molecular Cell Biology, 2020Ankit Salhotra +2 more
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