Results 41 to 50 of about 4,190,471 (295)

Osteopenia in a Mouse Model of Spinal Cord Injury: Effects of Age, Sex and Motor Function

Biology, 2022
After spinal cord injury (SCI), 80% of individuals are diagnosed with osteopenia or osteoporosis. The dramatic loss of bone after SCI increases the potential for fractures 100-fold, with post-fracture complications occurring in 54% of cases. With the age
Michelle A. Hook, Alyssa Falck, Ravali Dundumulla, Mabel Terminel, Rachel Cunningham, Arthur Sefiani, Kayla Callaway, Dana Gaddy, Cédric G. Geoffroy   +8 more
doaj   +1 more source

Adjusting bone mass for differences in projected bone area and other confounding variables: an allometric perspective. [PDF]

, 2002
The traditional method of assessing bone mineral density (BMD; given by bone mineral content [BMC] divided by projected bone area [Ap], BMD = BMC/Ap) has come under strong criticism by various authors. Their criticism being that the projected bone "area"
Roger L. Holder, Nevill, AM, Holder, Roger, Maffulli, Nicola, Lau, Joseph T. F., Warren T. K. Lee, Lee, WTK, Jack C. Y. Cheng, Nevill, Alan M., Alan M. Nevill, Lee, Warren T. K., Lau, JTF, Joseph T. F. Lau, Maffulli, N, Leung, Sophie S. S. F., Holder, Roger L., Cheng, Jack C. Y., Nicola Maffulli, Cheng, JCY, Leung, SSSF, Sophie S. S. F. Leung   +20 more
core   +1 more source

Provider and Parent Perspectives on Prioritizing the “Asking and Monitoring” Pediatric Cancer Psychosocial Standards of Care

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families (“Standards”) are evidence‐based guidelines for psychosocial care in pediatric oncology. Care related to the three “Asking and Monitoring” Standards—Assessment of Psychosocial Needs, Assessment of Financial Needs, and Monitoring Neurocognitive Problems ...
Julia B. Tager, Natalie Koskela‐Staples, Emily M. Pariseau, Michele Scialla, Kimberly Buff, Lori Wiener, Victoria Sardi Brown, Anne E. Kazak, Kimberly S. Canter   +8 more
wiley   +1 more source

PPAR Gamma Activity and Control of Bone Mass in Skeletal Unloading

PPAR Research, 2006
Bone loss occuring with unloading is associated with decreased osteoblastogenesis and increased bone marrow adipogenesis, resulting in bone loss and decreased bone formation.
P. J. Marie, K. Kaabeche
doaj   +1 more source

Parkin Inhibits RANKL-Induced Osteoclastogenesis and Ovariectomy-Induced Bone Loss

Biomolecules, 2022
Osteoporosis and osteoporotic fractures comprise a substantial health and socioeconomic burden. The leading cause of osteoporosis is an imbalance in bone formation and bone resorption caused by hyperactive osteoclasts.
Weiduo Hou, Mo Chen, Chenyi Ye, Erman Chen, Weixu Li, Wei Zhang   +5 more
doaj   +1 more source

Effects of smoking on tibial and radial bone mass and strength may diminish with age [PDF]

, 2010
Purpose: The purpose of the study was to assess the effect of cigarette smoking on indicators of bone strength across a wide age range, controlling for physical activity and neuromuscular performance. Methods:Weconducted a cross-sectional study with 41
Rittweger, Jörn, Wüst, Robert C.I., Morse, Christopher I., Wilks, Désirée C., Morse, Christopher I, Wüst, Rob C I, Degens, Hans, Winwood, Keith L., Wilks, Désirée C, Wüst, Rob C I; id_orcid, Winwood, Keith, Wüst, Rob   +11 more
core   +1 more source

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source

Lipid Signalling in Human Immune Response and Bone Remodelling under Microgravity

Applied Sciences, 2020
Since the first Apollo mission in 1969, microgravity has been linked to many alterations of astronauts’ physiology, among which immunosuppression, altered inflammation and bone loss represent relevant examples.
Marina Fava, Alessandro Leuti, Mauro Maccarrone   +2 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source