Results 51 to 60 of about 4,190,471 (295)

Bone Health Issues in Patients with Prostate Cancer: An Evidence-Based Review

The World Journal of Men's Health, 2020
Bone health in prostate cancer patients represents a prerequisite for acceptable quality of life and optimal outcome of this disease. The major threat for bone health in prostate cancer displays cancer treatment induced bone loss as well as the ...
Moritz Maas, Arnulf Stenzl, Tilman Todenhöfer   +2 more
doaj   +1 more source

Naringenin is a Potential Anabolic Treatment for Bone Loss by Modulating Osteogenesis, Osteoclastogenesis, and Macrophage Polarization

Frontiers in Pharmacology, 2022
Bone undergoes constant remodeling of formation by osteoblasts and resorption by osteoclasts. In particular, macrophages have been reported to play an essential role in the regulation of bone homeostasis and regeneration.
Xin Zhou, Zheng Zhang, Zheng Zhang, Weiwei Jiang, Miao Hu, Miao Hu, Yichen Meng, Wenfang Li, Xuhui Zhou, Ce Wang   +9 more
doaj   +1 more source

Bone Loss and Inhaled Glucocorticoids

New England Journal of Medicine, 2002
Comparisons between patients with mild asthma and those with persistent asthma who are receiving high doses of inhaled glucocorticoids must include a careful evaluation of base-line characteristics.2 Table 2 of the article shows that the 28 women who did not use inhaled glucocorticoids weighed less than the 42 women who required more than eight puffs ...
van Staa, Tjeerd-Pieter, Leufkens, Bert, Cooper, Cyrus   +2 more
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Stability of the Implant–Alveolar Bone Complex According to the Peri-Implant Bone Loss and Bone Quality: A Finite Element Analysis Study

Applied Sciences
Peri-implant bone loss and bone quality significantly affect the biomechanical stability and long-term success of dental implants. This study used finite element analysis to evaluate the stress distribution and deformation behavior of implants and ...
Youngjae Yoon, Jae-Eun Kim, Eunji Kim, Soyeon Park, Inyeong Kang, Yong-Dae Kwon   +5 more
doaj   +1 more source

SHIP1 Activator AQX-1125 Regulates Osteogenesis and Osteoclastogenesis Through PI3K/Akt and NF-κb Signaling

Frontiers in Cell and Developmental Biology, 2022
With the worldwide aging population, the prevalence of osteoporosis is on the rise, particularly the number of postmenopausal women with the condition.
Xudong Xie, Xudong Xie, Liangcong Hu, Liangcong Hu, Bobin Mi, Bobin Mi, Adriana C. Panayi, Hang Xue, Hang Xue, Yiqiang Hu, Yiqiang Hu, Guodong Liu, Lang Chen, Lang Chen, Chenchen Yan, Chenchen Yan, Kangkang Zha, Kangkang Zha, Ze Lin, Wu Zhou, Wu Zhou, Fei Gao, Fei Gao, Guohui Liu, Guohui Liu   +24 more
doaj   +1 more source

Bone loss following spinal cord injury

Journal of Neurorestoratology, 2014
Ali H Otom, M Rami Al-AhmarRheumatology and Rehabilitation Department, Royal Rehabilitation Centre, King Hussein Medical Centre, Amman, JordanBackground: The purpose of this study was to evaluate the pattern of bone loss and its consequences in a group ...
Otom AH, Al-Ahmar MR
doaj  

Effects of resveratrol supplementation on methotrexate chemotherapy-induced bone loss [PDF]

, 2017
Intensive cancer chemotherapy is known to cause bone defects, which currently lack treatments. This study investigated the effects of polyphenol resveratrol (RES) in preventing bone defects in rats caused by methotrexate (MTX), a commonly used ...
Yu‐Wen Su, Tristan King, Xian, C., Pei Soo, Lee, Alice M. C., King, Tristan J., Ke‐Ming Chen, Shandala, T., Soo, Pei Pei, Tetyana Shandala, Su, Y., Howe, Peter R., Shandala, Tetyana, Alice Lee, Xian, Cory J., Su, Yu-Wen, Cory Xian, Chen, Ke-Ming, Chen, K., Peter Howe, Soo, P., Lee, A., Howe, P., King, T.   +23 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Anatomical sector analysis of load-bearing tibial bone structure during 90 days bed rest and 1- year recovery [PDF]

, 2011
The aim of this study was to investigate whether the bone response to long bed rest–related immobility and during subsequent recovery differed at anatomically different sectors of tibial epiphysis and diaphysis.
Sievänen, Harrir, Rittweger, Jörn, Hyttinen, Jari, Felsenberg, Dieter, Cervinka, Tomas   +4 more
core