Results 121 to 130 of about 6,967 (325)

Short-Term Clinical Results of Single-Injection Autologous Bone Marrow Aspirate Concentrate (BMAC) as a Therapeutic Option/Tool in Knee Osteoarthritis

Biologics
Purpose: Knee osteoarthritis (KOA) is a very common cartilage disorder affecting millions of people globally and is characterized by pain, stiffness, swelling, loss of articular cartilage, and osteophyte formation, resulting in disability.
Krishna Subramanyam, Subhadra Poornima, Satish Kumar, Qurratulain Hasan   +3 more
doaj   +1 more source

Arthroscopic Posterior Labral Repair in Professional Contact Athletes Restores Shoulder Stability and Enables Successful Return to Pre‐injury Competition

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To evaluate return‐to‐competition rates, posterior shoulder instability recurrences, and revision surgeries following arthroscopic posterior labral repair in this elite cohort. Methods A retrospective review of prospectively collected data included professional contact athletes undergoing primary arthroscopic posterior labral repair by a single
Ayham Jaber, Lorenz Fritsch, Michael Nocek, Christopher J. Hawryluk, Maximilian Hinz, Matthew T. Provencher, Peter J. Millett   +6 more
wiley   +1 more source

Characterization of bone marrow aspirate concentrate with thrombin used for repairing osteochondral lesions of the talus

Journal of Cartilage & Joint Preservation
: Introduction: Bone marrow aspirate concentrate (BMAC) is an autologous biological augment used in the treatment of osteochondral lesions of the talus. Several studies have reported the short-term efficacy of BMAC for repair of osteochondral lesions of
Tian Lan, Karina T. Wright, Nilesh Makwana, Andrew Bing, Charlotte H. Hulme, Helen S. McCarthy   +5 more
doaj   +1 more source

Single‐Cell RNA Sequencing Informs Precision Targeting of Monogenic Lupus Associated With IKZF1 Haploinsufficiency

Arthritis &Rheumatology, EarlyView.
Objective This study aimed to investigate the mechanisms of immune dysregulation in a pediatric patient with monogenic lupus driven by IKZF1 haploinsufficiency. Methods Peripheral immune cells from a patient with IKZF1 haploinsufficiency, patients with lupus with no currently known genetic mutations, and healthy controls were analyzed using single‐cell
Qi Zheng, Yejun Tan, Zhaoling Wang, Yanjie Qian, Qian Ma, Danping Shen, Meiping Lu   +6 more
wiley   +1 more source

Optimization of DNA extraction from human urinary samples for mycobiome community profiling. [PDF]

, 2019
IntroductionRecent data suggest the urinary tract hosts a microbial community of varying composition, even in the absence of infection. Culture-independent methodologies, such as next-generation sequencing of conserved ribosomal DNA sequences, provide an
Ackerman, A Lenore, Ackerman, James E, Anger, Jennifer Tash, Freeman, Michael R, Khalique, Muhammad Umair, Kim, Jayoung, NIH Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP), Tang, Jie, Underhill, David M   +8 more
core   +3 more sources

The fate of bone marrow edema after core decompression and bone marrow aspiration concentrate grafting for the hip

BMC Musculoskeletal Disorders
Bone marrow edema (BME) of the femoral head is a prevalent condition that can cause hip pain and is observed in patients as a standalone finding or in conjunction with degenerative or inflammatory conditions. There has been a lack of extensive study on the effectiveness of combining surgery with biological treatment for BME. The objective of this study
Su, Weiping, Ma, Boyan, Leng, Wenjie, Pan, Yixiao, Zhang, Wenxiu, Wu, Song, Peng, Zhi   +6 more
openaire   +2 more sources

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early‐Phase Oncology Drug Development

Clinical Pharmacology &Therapeutics, EarlyView.
Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović, Ingrid Tomljanović, Wieke H. Grievink, Diana R. Pereira, Michelle Osse, Peter van Balen, Maria J. Juachon, Marieke L. de Kam, Lisa Pagan, Manon A.A. Jansen, Matthijs Moerland, Jacobus J. Bosch   +11 more
wiley   +1 more source

Prospective double-blind randomised controlled trial protocol comparing bone marrow aspirate concentrate intra-articular injection combined with subchondral injection versus intra-articular injection alone for the treatment of symptomatic knee osteoarthritis [PDF]

, 2022
Simone Silva, Luca Andriolo, Angelo Boffa, Alessandro Di Martino, Davide Reale, Giulio Vara, Marco Miceli, Carola Cavallo, Brunella Grigolo, Stefano Zaffagnini, Giuseppe Filardo   +10 more
openalex   +1 more source

Measurable residual disease by multicolor flow cytometry in acute myeloid leukemia: A comparison of peripheral blood and bone marrow

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Measurable residual disease (MRD) monitoring by multiparameter flow cytometry (MFC) is well established in bone marrow (BM) samples for acute myeloid leukemia (AML), but its use in peripheral blood (PB) remains less developed. We adapted a semi‐automated and well validated MFC‐MRD assay, originally developed for BM, to PB aiming to evaluate ...
Jonas Schadt, Malte von Bonin, Uta Oelschlägel, Christoph Röllig, Christian Thiede, Leo Ruhnke, Martin Bornhäuser, Sebastian Brenner, Maximilian Alexander Röhnert   +8 more
wiley   +1 more source

A One Health overview, facilitating advances in comparative medicine and translational research. [PDF]

, 2016
Table of contentsA1 One health advances and successes in comparative medicine and translational researchCheryl StroudA2 Dendritic cell-targeted gorilla adenoviral vector for cancer vaccination for canine melanomaIgor Dmitriev, Elena Kashentseva, Jeffrey ...
Baron, David A, Bergman, Philip J, Bryan, Jeffrey N, Calvet, James P, Coates, Joan R, Cook, James L, Curiel, David T, Dmitriev, Igor, Duan, Dongsheng, Engiles, Julie B, Gandolfi, Barbara, Gaurnier-Hausser, Anita, Gnanandarajah, Josephine S, Gray, Falon, Guloy, Amado S, Harman, Robert J, Hays, Harlen D, Henry, Carolyn J, Huebner, Margie, Jacobs, Marc, Johnson, Gary S, Johnson, Gayle C, Karanu, Francis N, Kashentseva, Elena, Katz, Martin L, Laughlin, Danielle, LeBlanc, Amy K, Likins, Lee, Lyons, Leslie A, Mason, Nicola J, O'Brien, Dennis P, O'Connor, Daniel, Paterson, Yvonne, Reinero, Carol, Rindt, Hans, Robb, Edward J, Sabbagh, Ubadah, Skaff, Andrew, Stannard, James P, Stroud, Cheryl, Treml, Laura S, Wallecha, Anu, Webster, Debra A, Weiss, Mark L, Wyckoff, Gerald J   +44 more
core   +2 more sources