Results 111 to 120 of about 1,147,375 (265)

Bone-marrow-based augmentation in rotator cuff repair—from microfracture to bone marrow aspirate concentrate

<jats:title>Abstract</jats:title><jats:p>Rotator cuff tears are a major cause of shoulder dysfunction, and relatively high rates of rotator cuff re-tear persist despite surgical advancements, particularly in patients with poor ...
Verma, Nikhil, Khan, Zeeshan A., Rupp, Marco-Christopher, Villarreal, Juan, Chahla, Jorge   +4 more
core   +1 more source

Concurrent Germline RB1 & Mosaic TP53 in a Child With Multiple Childhood Cancers

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We report a patient with a pathogenic germline variant (PGV) in RB1 and somatic mosaicism for a pathogenic TP53 variant who developed three distinct types of childhood cancer: retinoblastoma, osteosarcoma, and myelodysplastic syndrome (MDS) before the age of 6 years.
Ole Haubjerg Nielsen, Ulrik Kristoffer Stoltze, Pernille Axél Gregersen, Marianne Hoffmann, Morten Lyng Høgild, Mette Klarskov Andersen, Lise Barlebo Ahlborn, Lisa Lyngsie Hjalgrim, Karin A. W. Wadt   +8 more
wiley   +1 more source

Injection of Leukocyte‐Poor Platelet‐Rich Plasma During Rotator Cuff Repair Can Increase Healing Rate but Does Not Affect Clinical Outcomes: A Systematic Review and Meta‐analysis of Randomized Controlled Trials

Arthroscopy, EarlyView.
Purpose To evaluate the efficacy of injected leukocyte‐poor platelet‐rich plasma (LP‐PRP) during arthroscopic rotator cuff repair, primarily in reducing failure rates and, secondarily, in improving shoulder function and clinical outcome. Methods A systematic review was performed in accordance with the Preferred Reporting Items for Systematic Review and
Charalampos Pitsilos, Dimitrios Rigkos, Byron Chalidis   +2 more
wiley   +1 more source

Injectable Cell-based Tissue Engineered Bone Formulations [PDF]

, 2010
PhDCurrent golden standard therapy for bone repair and regeneration involves the use of auto grafts. Nevertheless, there are many drawbacks associated with auto grafts including donor site morbidity, requirement for an invasive surgery, post-operative
Ahmadi, Raheleh
core   +3 more sources

Orthobiologic Injections Adjunctive to Cartilage‐Preserving Surgery May Improve Outcomes for Focal Knee Chondral Defects: A Systematic Review of Randomized Controlled Trials With Subgroup Meta‐analyses

Arthroscopy, EarlyView.
Purpose To perform a systematic review evaluating the efficacy of orthobiologic injections as adjuncts to cartilage‐preserving surgery in improving clinical, radiographic, and histologic outcomes in adults with focal knee cartilage defects. Methods Four databases (PubMed, MEDLINE, EMBASE, and Scopus) were searched through September 2025 for randomized ...
Benjamin Blackman, Alexandru Pulbere, Seth Ybema, Marc Daniel Bouchard, Prushoth Vivekanantha, Praveen Sritharan, Darren de SA, Olufemi R. Ayeni, Jeffrey Kay   +8 more
wiley   +1 more source

Availability and Pricing of Orthobiologic Knee Injections Vary by Practice Type but Not by Community Socioeconomic Vulnerability in Suburban New York

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To assess the availability, price transparency, and pricing of platelet‐rich plasma (PRP), bone marrow aspirate concentration, and stem cell injections for knee osteoarthritis (OA) among orthopaedic sports medicine (OSM) practices and alternative clinics in suburban New York and to evaluate the impact of the economic status of a population on ...
Tracy M. Tauro, Benjamin Hershfeld, Katharine Chen, Ran Lampert, Adam D. Bitterman, Randy M. Cohn, Nicholas A. Sgaglione   +6 more
wiley   +1 more source

Bone Marrow Aspirate Concentrate Harvest Techniques for the Sports Medicine Surgeon

Arthroscopy Techniques
The use of bone marrow aspirate concentrate (BMAC) as a surgical augment to enhance biologic healing has been gaining popularity in a variety of sports medicine procedures.
S. Allahabadi, Harry Jawanda, Zeeshan A. Khan, Christopher M. Brusalis, J. Chahla, Brian J. Cole, N. Verma   +6 more
semanticscholar   +1 more source

Bone Marrow Aspirate Concentrate for Cartilage Defects of the Knee: From Bench to Bedside Evidence

, 2017
Objective To critically evaluate the current basic science, translational, and clinical data regarding bone marrow aspirate concentrate (BMAC) in the setting of focal cartilage defects of the knee and describe clinical indications and future research ...
Adam B. Yanke, Eric J. Cotter, Kevin C. Wang, Susan Chubinskaya   +3 more
core   +1 more source

Augmentation of Arthroscopic Rotator Cuff Repair Using Enthesis Interpositional Allograft and Minced Autologous Subacromial Bursa

Arthroscopy Techniques, EarlyView.
Abstract Multiple strategies for rotator cuff augmentation have been developed to promote tendon healing and decrease retear rates. Previously published techniques and clinical studies have primarily emphasized biologic adjuncts intended to alter the local healing environment at the repair site or structural reinforcement with grafts.
Matthew D. Smith, Shyon K. Ahmadi, James M. Gregory   +2 more
wiley   +1 more source

Navigating the Therapeutic Landscape: A Comprehensive Review of Platelet-Rich Plasma and Bone Marrow Aspirate Concentrate in Knee Osteoarthritis

Cureus
This comprehensive review provides an in-depth analysis of platelet-rich plasma (PRP) and bone marrow aspirate concentrate (BMAC) as potential treatments for knee osteoarthritis.
Prashanth Balusani, Sandeep Shrivastava, Aditya Pundkar, Prathamesh S. Kale   +3 more
semanticscholar   +1 more source