Results 171 to 180 of about 1,604,632 (364)

A Modular Perfusion Bioreactor Platform for Simulating Bone Regeneration and Fracture Healing: Integrating Mechanical Loading and Dual Perfusion for Advanced In Vitro Models

Advanced Healthcare Materials, EarlyView.
A modular bioreactor platform was developed in order to replicate bone homeostasis and pathology, thereby integrating mechanical loading, dynamic perfusion, and a 3D‐printed microfluidic chamber. With precise control of environmental parameters and dual perfusion for composite tissue models, the system enhances physiological relevance for studying bone
Moritz Pfeiffenberger, Alexandra Damerau, Johannes Plank, Adel Ahmed, Mario Thiele, Jan Saam, Paula Hoff, Timo Gaber, Frank Buttgereit   +8 more
wiley   +1 more source

Expression of human adenosine deaminase in nonhuman primates after retrovirus-mediated gene transfer. [PDF]

, 1987
Primate bone marrow cells were infected with a retroviral vector carrying the genes for human adenosine deaminase (h-ADA) and bacterial neomycin resistance (neor). The infected cells were infused back into the lethally irradiated donor animals.
Bordignon, C, Eglitis, MA, Gillio, AP, Kantoff, PW, Karson, E, Kernan, NA, Kohn, DB, McLachlin, JR, Moen, RC, Yu, SF   +9 more
core  

Autologous Bone Marrow Mononuclear Cell Implantation and Its Impact on the Outcome of Patients With Critical Limb Ischemia　― Results of a Randomized, Double-Blind, Placebo-Controlled Trial ―

, 2017
B. Pignon, Marie‐Antoinette Sevestre, Lukshe Kanagaratnam, Gilles Pernod, Dominique Stéphan, Joseph Emmerich, Claude Clément, Gabrielle Sarlon, Carine Boulon, Claire Tournois, Philippe Nguyên   +10 more
openalex   +2 more sources

The bone marrow niche for haematopoietic stem cells

Nature, 2014
S. Morrison, D. Scadden
semanticscholar   +1 more source

Borate‐Ion‐Stimulated Macrophages Promote Osteogenic Differentiation of Mesenchymal Stem Cells

Advanced Healthcare Materials, EarlyView.
The immune responses of mouse macrophages stimulated by borate ions promote the osteogenic differentiation and mineralization of mouse bone marrow–derived mesenchymal stem cells in an ion‐dose‐dependent manner by providing cytokines, including BMP‐2.
Kazumasa Ikedo, Hiroki Hatakeyama, Sayaka Oguri, Akiko Obata, Toshihiro Kasuga   +4 more
wiley   +1 more source

Protocol for live imaging of transferred mouse bone marrow cells by two-photon microscopy. [PDF]

STAR Protoc, 2023
Sudo T, Yamashita E, Kikuta J, Ishii M.
europepmc   +1 more source

IL-2 receptor α chain (CD25JAC) expression defines a crucial stage in pre-B cell development [PDF]

, 2017
The analysis of the expression of the a chain of the IL-2 receptor (CD25.TAC) on the surface of B lineage cells In mouse bone marrow reveals that it is a useful marker to distinguish pre-B-I from pre-B-II cells.
Grawunder, Ulf, Karasuyama, Hajime, Melchers, Fritz, Rolink, Antonius, Winkler, Thomas H.   +4 more
core  

Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization.

Circulation Research, 1999
T. Asahara, H. Masuda, Tomono Takahashi, C. Kalka, Christopher Pastore, Marcy Silver, Marianne Kearne, M. Magner, J. Isner   +8 more
semanticscholar   +1 more source

Ascorbic Acid Modulates Collagen Properties in Glucocorticoid‐Induced Osteoporotic Bone: Insights into Chemical, Mechanical, and Biological Regulation

Advanced Healthcare Materials, EarlyView.
Osteoporosis from long‐term glucocorticoid (GIOP) use elevates susceptibility to fracture. This study shows GCs impair ascorbic acid (AA) metabolism in osteoblasts, collagen synthesis and extracellular matrix integrity. AA enhanced collagen biochemical and mechanical properties and restored osteoblast and endothelial function. These findings underscore
Micaila DE Curtis, Yoontae Kim, Rahul Patil, Xinran Zhang, Meth Jayatilake, Orelle Bulgin, Peter Lialios, Sana Surrency, Soraya Tarrah, Argyris K. Lazaris, Alison Grafton, James Williams IV, Seyedeh Boshra Nouraie, Maria Bizaki, Penelope Xeron, Edward Van Keuren, Jonathan E. Seppala, Evagelia C. Laiakis, Joanna B. Kitlinska, Stella Alimperti   +19 more
wiley   +1 more source

Visible Light Induced DLP‐Printed Oxygen‐Releasing TPMS Scaffolds Mitigate Early Hypoxia in Bone Defects

Advanced Healthcare Materials, EarlyView.
Visible light‐induced digital light processing 3D printed Primitive‐triply periodic minimal surface hydrogels embed CaO2–Si core–shell nanoparticles to deliver short‐term oxygen during the avascular window. The scaffolds maintain cytocompatibility, elevate osteopontin in vitro, and enhance calvarial defect repair in vivo without toxicity.
Anastasia B. Timoshenko, Ali Ghasemkhani, Chanul Kim, Domenic J. Cordova, Maria Astudillo Potes, Valeria Aceves, Indranath Mitra, Justin E. Bird, Ryan S. Gray, Stephanie K. Seidlits, Benjamin D. Elder, Maryam Tilton   +11 more
wiley   +1 more source