Results 181 to 190 of about 630,798 (317)

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

Advanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia, Chenfei Kong, Xiaoming Zhao, Naixu Shi, Jinlan Jiang, Ping Li   +5 more
wiley   +1 more source

Automatic computational classification of bone marrow cells for B cell pediatric leukemia using UMAP. [PDF]

BioData Min
Niño-López A, Martínez-Rubio Á, Picón-González R, Castillo Robleda A, Ramírez Orellana M, Chulián S, Rosa M.   +6 more
europepmc   +1 more source

All the PNS is a Stage: Transplanted Bone Marrow Cells Play an Immunomodulatory Role in Peripheral Nerve Regeneration. [PDF]

ASN Neuro, 2023
Piñero G, Vence M, Aranda ML, Cercato MC, Soto PA, Usach V, Setton-Avruj PC.   +6 more
europepmc   +1 more source

Hepatocyte PIEZO1 Negatively Regulates Lipogenesis and Ameliorates MASLD by Sensing Membrane Tension and Activating AMPK

Advanced Science, EarlyView.
Hepatocytes are subjected to increased membrane tension along with lipid accumulation. Loss of PIEZO1 exacerbates high‐fat diet‐induced MASLD in mice. Activation of PIEZO1 alleviates high‐fat diet‐induced MASLD in mice. PIEZO1 negatively regulates de novo lipogenesis through activation of CaMKK2‐AMPK pathway. ABSTRACT Liver is a central organ for lipid
Hui Chen, Qimeng Wang, Ke Yang, Qinghai Lian, Xuyun Peng, Zhiyong Gong, Xinyi Zhao, Yong Wu, Tian Tao, Siqi Xu, Yifan Chen, Xiaoyan Tang, Jinghui Guo, Geyang Xu, Qi Zhang   +14 more
wiley   +1 more source

P1450: AUTOLOGOUS STEM CELL TRANSPLANTATION INDUCES HIGHER LEVEL OF EXHAUSTED T-CELLS IN DLBCL PATIENTS BEFORE LEUKAPHERESIS FOR CAR-T CELL THERAPY.

HemaSphere, 2022
M. Farina, M. Chiarini, C. Almici, A. Beghin, E. Accorsi Buttini, A. Galvagni, E. Ferrari, A. Bianchetti, F. Zuccalà, S. Piva, I. Volonghi, L. Poli, D. Moratto, A. Leoni, F. Re, K. Bosio, S. Bernardi, N. Polverelli, A. Turra, E. Morello, C. Cattaneo, A. Lanfranchi, M. Malagola, D. Brugnoni, A. Re, D. Russo   +25 more
doaj   +1 more source

In vitro Comparison of Cytotoxicity and Osteoclastogenesis of Four Bioceramic Sealers in Murine Bone Marrow Cells. [PDF]

Int Dent J
Chen Z, Sun X, Wang Z, Chang Z, Zhu L, Wang L.   +5 more
europepmc   +1 more source

Additional improvement in regional myocardial ischemia after intracardiac injection of bone marrow cells during CABG surgery. [PDF]

Front Cardiovasc Med, 2023
Gowdak LHW, Schettert IT, Rochitte CE, de Carvalho LP, Vieira MLC, Dallan LAO, de Oliveira SA, César LAM, Brito JOR, Guarita-Souza LC, de Carvalho ACC, Krieger JE.   +11 more
europepmc   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, EarlyView.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Wild-type bone marrow cells repopulate tissue resident macrophages and reverse the impacts of homozygous CSF1R mutation. [PDF]

PLoS Genet
Carter-Cusack D, Huang S, Keshvari S, Patkar O, Sehgal A, Allavena R, Byrne RAJ, Morgan BP, Bush SJ, Summers KM, Irvine KM, Hume DA.   +11 more
europepmc   +2 more sources

TNFα stimulates osteoclastogenesis and expression of CX3CL1 in non-adherent bone marrow cells. [PDF]

Biochem Biophys Rep
Otsuka Y, Hattori N, Aoki H, Toriuchi K, Inoue Y, Hayashi H, Kuroyanagi G, Kawaguchi Y, Waguri-Nagaya Y, Aoyama M.   +9 more
europepmc   +1 more source