This review highlights recent progress in nanocarriers targeting pattern recognition receptors (PRRs), including Toll‐like and NOD‐like receptors, for enhancing the treatment of bacterial sepsis and related complications. These nanomedicines deliver antibiotics and anti‐inflammatory agents while modulating immune responses.
Eman A. Ismail+3 more
wiley +1 more source
Hippo Signaling Pathway Involvement in Osteopotential Regulation of Murine Bone Marrow Cells Under Simulated Microgravity. [PDF]
Tyrina E+3 more
europepmc +1 more source
MarrowDLD: a microfluidic method for label-free retrieval of fragile bone marrow cells
Porro G+7 more
europepmc +1 more source
Evaluation of the effects of disulfiram, an alcohol-aversive agent with anti-cancer activity, on mouse bone marrow cells. [PDF]
Park SR, Joo HG.
europepmc +1 more source
Lymphoid and CXCR4 Cell Targeted Lipid Nanoparticles Facilitate HIV‐1 Proviral DNA Excision
Advancements in ART improve HIV‐1 patient outcomes but are unable to eliminate latent viral DNA. To address this, CXCR4‐targeted lipid nanoparticles (T‐LNPs) for delivering CRISPR‐Cas9 to excise HIV‐1 DNA in infected cells are developed. These T‐LNPs achieve ≈60% HIV‐1 DNA excision efficacy in blood and splenic tissue, demonstrating promise for ...
Sudipta Panja+6 more
wiley +1 more source
Metformin impacts the differentiation of mouse bone marrow cells into macrophages affecting tumour immunity. [PDF]
Scafidi A+15 more
europepmc +1 more source
Peptidylarginine deiminase 4 deficiency in bone marrow cells prevents plaque progression without decreasing atherogenic inflammation in apolipoprotein E-knockout mice. [PDF]
Paunel-Görgülü A+5 more
europepmc +1 more source
Failure of syngeneic bone marrow cells to protect against MC-induced lymphoma in dba/2 mice [PDF]
Louise Chen, I. Berenblum
openalex +1 more source
Differential Phase Contrast Imaging to Predict MSC Immune Function
This work employs quantitative differential phase contrast (qDPC) imaging technique to non‐invasively extract morphological features from live Mesenchymal Stromal Cells (MSCs) for single cell prediction on cell immunomodulatory capacity. This work establishes a foundation for scalable, non‐destructive monitoring of MSCs immunomodulatory capacity ...
Kejie Rui+5 more
wiley +1 more source
Bone marrow cells for cardiac repair
openaire +3 more sources