Results 11 to 20 of about 5,258,740 (285)
Bone marrow mononuclear cells and acute myocardial infarction [PDF]
Stem Cell Research & Therapy, 2012 Stem cell transplantation is emerging as a potential therapy to treat heart diseases. Promising results from early animal studies led to an explosion of small, non-controlled clinical trials that created even further excitement by showing that stem cell transplantation improved left ventricular systolic function and enhanced remodelling.
Arnous, S +3 more
openaire +5 more sources
Bone marrow derived cells as endothelial precursors and the role of multi-potent progenitor cells in repairing ischaemic tissues. [PDF]
, 2007 PhDIntroduction: Atherosclerosis and its complications are a major cause of death and disability and it remains a major challenge to develop new therapies for patients with irreversible end organ damage and ongoing ischaemia.
Wragg, Andrew
core +4 more sources
The role of bone marrow derived cells in cardiac repair [PDF]
, 2012 PhDCurrent pharmacological therapies fail to address the final end-point of cardiac ischaemia — the death and dysfunction of cardiomyocytes. Advances in stem cell biology have provided hope, for the first time, of addressing this underlying pathology.
Lovell, Matthew J.
core +4 more sources
Cytokine production by bone marrow mononuclear cells in inherited bone marrow failure syndromes [PDF]
British Journal of Haematology, 2013 SummaryFanconi anaemia (FA), dyskeratosis congenita (DC), Diamond‐Blackfan anaemia (DBA), and Shwachman‐Diamond syndrome (SDS) are characterized by the progressive development of bone marrow failure. Overproduction of tumour necrosis factor‐α (TNF‐α) from activated bone marrow T‐cells has been proposed as a mechanism of FA‐related aplasia. Whether such
Ken, Matsui +3 more
openaire +2 more sources
Protein and gene expression analyses in bone marrow stem cells mediated restoration of myocardium after ischemic insult [PDF]
, 2010 PhDMyocardial Infarction (MI) is caused by occlusion of the coronary artery following atheromatous plaque rupture, the subsequent ischemia in the myocardium leads to myocyte necrosis unless treated quickly. Bone marrow derived stem cell treatment is a
Lee, Kate L
core +4 more sources
Prednisolone and vitamin D(3) modulate oxidative metabolism and cell death pathways in blood and bone marrow mononuclear cells [PDF]
The Ukrainian Biochemical Journal, 2016 The study was designed to evaluate reactive oxygen species (ROS)/nitric oxide (NO) formation and apoptotic/necrotic cell death elicited by prednisolone in peripheral blood and bone marrow mononuclear cells and to define the efficacy of vitamin D3 to ...
I. O. Shymanskyy +5 more
doaj +1 more source
Journal of Applied Veterinary Sciences, 2020 Stem cell therapy is considered an important and innovative tool for applied research in andrology, especially in infertility; therefore, it was later adapted as potential therapeutic agents. This study aimed to evaluate rat mononuclear bone marrow cells'
Ahmed M. Mousbah +3 more
doaj +1 more source
Intracarotid administration of human bone marrow mononuclear cells in rat photothrombotic ischemia [PDF]
, 2010 Background: Increasing evidence suggests that cell therapy improves functional recovery in experimental models of stroke and myocardial infarction.
Wolf-Rüdiger Schäbitz +13 more
core +1 more source
Brazilian Journal of Cardiovascular Surgery, 2014 Objective: We tested the hypothesis that direct intramyocardial injection of bone marrow mononuclear cells in patients with non-ischemic dilated cardiomyopathy can improve left ventricular function and physical capacity.
Roberto T. Sant'Anna +7 more
doaj +1 more source
Frontiers in Oncology, 2022 Myelodysplastic syndrome (MDS) is a hematological disorder characterized by abnormal stem cell differentiation and a high risk of acute myeloid leukemia transformation.
Arlindo A. Moura +34 more
doaj +1 more source