Results 21 to 30 of about 104,182 (257)

Angiotensin-(1–7) stimulates hematopoietic progenitor cells in vitro and in vivo

Haematologica, 2009
Effects of angiotensin (Ang)-(1–7), an AngII metabolite, on bone marrow-derived hematopoietic cells were studied. We identified Ang-(1–7) to stimulate proliferation of human CD34+ and mononuclear cells in vitro.
Silvia Heringer-Walther, Klaus Eckert, Sarah-Mai Schumacher, Lutz Uharek, Annika Wulf-Goldenberg, Florian Gembardt, Iduna Fichtner, Heinz-Peter Schultheiss, Kathy Rodgers, Thomas Walther   +9 more
doaj   +1 more source

Characterization of Bone Marrow Mononuclear Cells on Biomaterials for Bone Tissue EngineeringIn Vitro [PDF]

BioMed Research International, 2015
Bone marrow mononuclear cells (BMCs) are suitable for bone tissue engineering. Comparative data regarding the needs of BMC for the adhesion on biomaterials and biocompatibility to various biomaterials are lacking to a large extent. Therefore, we evaluated whether a surface coating would enhance BMC adhesion and analyze the biocompatibility of three ...
Dirk Henrich, René Verboket, Alexander Schaible, Kerstin Kontradowitz, Elsie Oppermann, Jan C. Brune, Christoph Nau, Simon Meier, Halvard Bonig, Ingo Marzi, Caroline Seebach   +10 more
openaire   +3 more sources

PET/CT in Evaluation Bone Marrow Infiltration in Malignant Lymphoma. Badr, S1. Abdelwahab, M.A1 and Moustafa, H2. 1NCI and 2NEMROCK Centre, Cairo University, Egypt. [PDF]

Egyptian Journal of Nuclear Medicine, 2016
The bone marrow is found within the central cavities of axial and long bones. It consists of hematopoietic tissue islands and adipose cells surrounded by vascular sinuses interspersed within a meshwork of trabecular bone. It accounts for approximately 5%
doaj   +1 more source

Cell therapy: A potential solution for the healing of bone cavities

Heliyon, 2021
Aim: To Explore whether the use of autologous BMMNCs as a cell therapy technique will improve the healing of bone cavities in vivo. Methodology: After achieving proper anesthesia, mononuclear cells were isolated from iliac crest's bone marrow aspirates ...
Sara El-Gindy, Maram Farouk Obeid, Kareim Mostafa Elbatouty, Elham Elshaboury, Ehab Hassanien   +4 more
doaj   +1 more source

Mouse mesenchymal stem cells can support human hematopoiesis both in vitro and in vivo: the crucial role of neural cell adhesion molecule

Haematologica, 2010
Background We previously established a mesenchymal stem cell line (FMS/PA6-P) from the bone marrow adherent cells of fetal mice. The cell line expresses a higher level of neural cell adhesion molecule and shows greater hematopoiesis-supporting capacity ...
Xiaoli Wang, Hiroko Hisha, Tomomi Mizokami, Wenhao Cui, Yunze Cui, Aiping Shi, Changye Song, Satoshi Okazaki, Qing Li, Wei Feng, Junko Kato, Susumu Ikehara   +11 more
doaj   +1 more source

The role of bone marrow mononuclear cell-conditioned medium in the proliferation and migration of human dermal fibroblasts

Cellular & Molecular Biology Letters, 2017
Background Several recent studies have demonstrated the great potential of bone marrow cells in regenerative medicine, not only for their ability to differentiate to match a damaged cell type, but also because they synthesize and release various growth ...
Yolanda Menéndez-Menéndez, Jesús Otero-Hernández, Jose Antonio Vega, Marcos Pérez-Basterrechea, Silvia Pérez-López, María Álvarez-Viejo, Amaia Ferrero-Gutiérrez   +6 more
doaj   +1 more source

Effects of lipoxygenase metabolites of arachidonic acid on the growth of human mononuclear marrow cells and marrow stromal cell cultures

Mediators of Inflammation, 1998
The effects of various lipoxygenase metabolites of arachidonic acid (AA) were investigated on the growth of freshly isolated human bone marrow mononuclear cells and marrow stromal cell cultures. LTB4, LXA4, LXB4, 12-HETE and 15-HETE (1 μM) decreased [3H]-
V. Desplat, F. Dupuis, F. Trimoreau, C. Dulery, V. Praloran, Y. Denizot   +5 more
doaj   +1 more source

Protocol for collection and separation of bone marrow mononuclear cells in Chlorocebus aethiops

Pesquisa Veterinária Brasileira, 2016
: Chlorocebus aethiops is a species of non-human primate frequently used in biomedical research. Some research involves this species as an experimental model for various diseases and possible treatment with stem cells.
Érika Branco, Klena Sarges Marruaz Silva, Maria de Fátima Assis, Edivaldo Herculano Corrêa de Oliveira, Ana Rita de Lima, Ana Cleide Guimbal de Aquino, Rosa Cabral, Maria Angelica Miglino   +7 more
doaj   +1 more source

Role of Bone Marrow Mononuclear Cell Seeding for Nanofiber Vascular Grafts [PDF]

Tissue Engineering Part A, 2018
Electrospinning is a promising technology that provides biodegradable nanofiber scaffolds for cardiovascular tissue engineering. However, success with these materials has been limited, and the optimal combination of scaffold parameters for a tissue-engineered vascular graft (TEVG) remains elusive.
Takuma, Fukunishi, Cameron A, Best, Chin Siang, Ong, Tyler, Groehl, James, Reinhardt, Tai, Yi, Hideki, Miyachi, Huaitao, Zhang, Toshiharu, Shinoka, Christopher K, Breuer, Jed, Johnson, Narutoshi, Hibino   +11 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source