Results 211 to 220 of about 104,182 (257)
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Neovascularization and bone regeneration by implantation of autologous bone marrow mononuclear cells
Biomaterials, 2005We examined whether transplantation of autologous bone marrow mononuclear cells (BM-MNCs) can augment neovascularization and bone regeneration of bone marrow in femoral bone defects of rabbits. Gelatin microspheres containing basic fibroblast growth factor (bFGF) were prepared for the controlled release of bFGF.
Yuji Yasunaga +2 more
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Cytotoxic Effector Capacity of Bone Marrow Mononuclear Cells
International Archives of Allergy and Applied Immunology, 2009Purified mononuclear cells from guinea pig bone marrow possess highly efficient cytotoxic effector cell capabilities in the phytohemagglutinin-induced cellular cytotoxicity and antibody-dependent cellular cytotoxicity assays against chicken red blood cell targets.
A S, Fauci, J E, Balow, K R, Pratt
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Hydrogen inhibits the osteoclastogenesis of mouse bone marrow mononuclear cells
Materials Science and Engineering: C, 2020Hydrogen (H2) is one of the major biodegradation products of magnesium (Mg) alloys implanted for bony fracture healing and reconstruction; H2 thus plays a significant role in the regulation of local microenvironment and the biology of resident cells. The interactions between the H2 and the local cells are of great interest, and a full understanding of ...
Liu, Yong +4 more
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Cardiovascular Radiation Medicine, 2003
Bone marrow stem cells have been shown to differentiate into various phenotypes including cardiomyocytes, vascular endothelial cells and smooth muscle. Bone marrow stem cells are mobilized and home in to areas of injured myocardium where they are involved in tissue repair.
Ron, Waksman, Richard, Baffour
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Bone marrow stem cells have been shown to differentiate into various phenotypes including cardiomyocytes, vascular endothelial cells and smooth muscle. Bone marrow stem cells are mobilized and home in to areas of injured myocardium where they are involved in tissue repair.
Ron, Waksman, Richard, Baffour
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Accessory cells unrelated to mononuclear phagocytes and not of bone marrow origin
Immunology Today, 1982The induction and regulation of immune responses require the participation of cells which maintain lymphocyte viability, promote necessary cellular interactions, secrete immunoregulatory molecules and present antigen. These are accessory cells, and their function is not antigen-specific. Classically, cells of the mononuclear phagocyte lineage have been
P E, Lipsky, J R, Kettman
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A fully automated method for mononuclear bone marrow cell concentration
Journal of Clinical Apheresis, 1992AbstractWe describe our experience in processing 40 bone marrow aspirates harvested for autotransplantation from patients with several hematological diseases using the CS‐3000 blood cell separator. The bone marrow of the first 30 patients was processed by a semiautomated method, and a fully automated procedure was used for the remaining 10 cases.Both ...
J M, Rodriguez +7 more
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Reparation of the Myocardium after Transplantation of Mononuclear Bone Marrow Cells
Bulletin of Experimental Biology and Medicine, 2011Safety and efficiency of intracoronary transventricular transplantation of autologous mononuclear bone marrow cells in rats with postinfarction cardiosclerosis were studied. The cells migrated to the damaged area and were detected only in the cicatricial tissue; they have fibroblast-like phenotype and some of them were stained with Fapα (marker of ...
Yu P, Baikova +7 more
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Intravenous autologous bone marrow mononuclear cells for ischemic stroke
Annals of Neurology, 2011AbstractObjective:Cellular therapy is an investigational approach for stroke. Mononuclear cells (MNCs) from the bone marrow reduce neurological deficits in animal stroke models. We determined if autologous MNC infusion was feasible and safe in patients with ischemic stroke.Methods:We conducted an open‐label prospective study of a bone marrow harvest ...
Sean I, Savitz +9 more
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Veterinary Research Communications, 2008
The aim of the study is to evaluate the clinical application in veterinary orthopedics of bone marrow mononuclear cells (BMMNCs) and cultured bone marrow stromal cells (cBMSCs) for the treatment of some orthopaedic lesions in the dog. The authors carried out a clinical study on 14 dogs of different breed, age and size with the following lesions: 1 bone
CROVACE, Antonio +5 more
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The aim of the study is to evaluate the clinical application in veterinary orthopedics of bone marrow mononuclear cells (BMMNCs) and cultured bone marrow stromal cells (cBMSCs) for the treatment of some orthopaedic lesions in the dog. The authors carried out a clinical study on 14 dogs of different breed, age and size with the following lesions: 1 bone
CROVACE, Antonio +5 more
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Bone Marrow-Derived Mononuclear Cells
2017Stem cell-based approaches have recently attracted much attention owing to their potential therapeutic effects in patients with stroke. Bone marrow-derived mononuclear cells (MNCs), a source of stem cells, contain populations of lymphocytes, mesenchymal and hematopoietic stem cells, and hematopoietic and endothelial progenitor cells.
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