Results 221 to 230 of about 104,182 (257)

Concentration of bone marrow mononuclear cells using a programmable blood cell separator

Journal of Clinical Apheresis, 1991
AbstractBone marrow was collected from adult patients with various solid tumors who consented to participate in a study of myelo‐ablative chemotherapy followed by autologous bone marrow rescue. Twenty marrow suspensions were processed by using standard Procedure 3 (PRO‐3) for lymphocytapheresis without modification. A modified Procedure 1 (M‐PRO‐1) for
A R, Orlina, J C, Conant, P J, DeChristopher, A T, Lin   +3 more
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In vitro differentiation of mouse bone marrow mononuclear cells into hepatocyte-like cells

Hepatology Research, 2005
: It is imperative to explore some ways to gain the functional hepatocytes for hepatocyte transplantation. Bone marrow stem cells can differentiate into hepatocytes in vivo and in vitro. We select fibroblast growth factor-4 (FGF-4), oncostatin M (OSM), hepatocyte growth factor (HGF) and epithermal growth factor (EGF) as differentiation factors, and ...
Xiao-Lei, Shi, Yu-Dong, Qiu, Xin-Yu, Wu, Ting, Xie, Zhang-Hua, Zhu, Lei-Lei, Chen, Lei, Li, Yi-Tao, Ding   +7 more
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Cell Therapy with Bone Marrow Mononuclear Cells in Elastase-Induced Pulmonary Emphysema

Stem Cell Reviews and Reports, 2012
Emphysema is characterized by destruction of alveolar walls with loss of gas exchange surface and consequent progressive dyspnea. This study aimed to evaluate the efficiency of cell therapy with bone marrow mononuclear cells (BMMC) in an animal model of elastase-induced pulmonary emphysema.
Longhini-dos-Santos, Nathalia, Barbosa-de-Oliveira, Valter Abraão, Kozma, Rodrigo Heras, de Faria, Carolina Arruda, Stessuk, Talita, Frei, Fernando, Ribeiro-Paes, João Tadeu   +6 more
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The thiol-proteindisulfide oxidoreductase in human mononuclear cells of blood and bone marrow

Acta Histochemica, 1986
The in vivo function of the thiol-proteindisulfide oxidoreductase (TPO, EC 1.8.4.2; proteindisulfide isomerase, EC 5.3.4.1) in biosynthesis of immunoglobulin was investigated by studying the enzyme content in human lymphoid and other cells by an immunocytochemical method. In contrast to peripheral blood, B lymphocytes which showed no or no demonstrable
S, Ansorge, H W, Mansfeld, C, Held, L, Broodtaerts, B, van Camp   +4 more
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Intracoronary Injection of Mononuclear Bone Marrow Cells in Acute Myocardial Infarction

New England Journal of Medicine, 2006
Previous studies have shown improvement in left ventricular function after intracoronary injection of autologous cells derived from bone marrow (BMC) in the acute phase of myocardial infarction. We designed a randomized, controlled trial to further investigate the effects of this treatment.Patients with acute ST-elevation myocardial infarction of the ...
Ketil, Lunde, Svein, Solheim, Svend, Aakhus, Harald, Arnesen, Michael, Abdelnoor, Torstein, Egeland, Knut, Endresen, Arnfinn, Ilebekk, Arild, Mangschau, Jan G, Fjeld, Hans Jørgen, Smith, Eli, Taraldsrud, Haakon Kiil, Grøgaard, Reidar, Bjørnerheim, Magne, Brekke, Carl, Müller, Einar, Hopp, Asgrimur, Ragnarsson, Jan E, Brinchmann, Kolbjørn, Forfang   +19 more
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Bone marrow-derived mononuclear cell populations in pediatric and adult patients

Cytotherapy, 2009
Many clinical trials are currently evaluating the safety and efficacy of autologous bone marrow (BM) mononuclear cells (MNC) for various pathologies in younger and older non-cancer patients. Concern has been raised that autologous MNC derived from elderly patients may be less effective as a therapeutic option.We compared the MNC yield, viability ...
Matthew T, Harting, Charles S, Cox, Mary-Clare, Day, Peter, Walker, Adrian, Gee, Miranda M, Brenneman, James C, Grotta, Sean I, Savitz   +7 more
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Bone marrow mononuclear cell therapy in ischaemic stroke: a systematic review

Acta Neurologica Scandinavica, 2016
Bone marrow mononuclear cell (BM-MNC) therapy has emerged as a potential therapy for the treatment of stroke. We performed a systematic review of published studies using BM-MNC therapy in patients with ischaemic stroke (IS). Literature was searched using MEDLINE, PubMed, EMBASE, Trip Database, Cochrane library and clinicaltrial.gov to identify studies ...
A, Kumar, M, Prasad, V P, Jali, A K, Pandit, S, Misra, P, Kumar, K, Chakravarty, P, Kathuria, A, Gulati   +8 more
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Feasibility and limits of bone marrow mononuclear cell expansion following irradiation

International Journal of Radiation Biology, 2004
To define the ability of bone marrow mononuclear cells (BMMNC) to expand after irradiation and to determine the amount of apoptosis in irradiated expanded cells.Non-human primate BMMNC were irradiated in vitro at doses ranging from 0 to 4 Gy and were cultured during 1 week in the presence of interleukin 3, interleukin 6, stem cell factor ...
J M, Bertho, E, Mathieu, A, Lauby, J, Frick, C, Demarquay, P, Gourmelon, N C, Gorin, D, Thierry   +7 more
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The antidepressant effect of bone marrow mononuclear cell transplantation in chronic stress

Journal of Psychopharmacology, 2019
Background: Inflammation could be a risk factor for the development of depression and change the outcome of this common chronic-recurrent mental disorder. Aims: This study aimed to investigate if bone marrow mononuclear cell (BMMC ...
Pedro Antônio Schmidt do Prado-Lima, Guilherme Ary Onsten, Gutierre Neves de Oliveira, Guilherme Camargo Brito, Isadora Machado Ghilardi, Eduardo Vieira de Souza, Paula Gabrielli dos Santos, Simone Denise Salamoni, Denise Cantarelli Machado, Marta Medeiros Frescura Duarte, Fernanda Barbisan, Ivana Beatrice Mânica da Cruz, Zaquer Suzana Munhoz Costa-Ferro, Jaderson Costa daCosta   +13 more
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Intra-arterial bone marrow mononuclear cells for stroke

The Lancet Neurology, 2023
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