Results 41 to 50 of about 823,617 (410)

Leukemia with Plasma Cells — Case Report

Journal of Interdisciplinary Medicine, 2017
Plasma cell leukemia (PCL) is one of the most aggressive monoclonal gammopathies, being characterized by the presence of more than 20% of plasma cells in the peripheral blood and an absolute number of these cells of more than 2×109, with different ...
Benedek István, Benedek István, Köpeczi Judit Beáta, Kéri Johanna Sándor, Pakucs Annamária, Jakab Szende, Lázár Erzsébet   +6 more
doaj   +1 more source

The oncometabolite R-2-hydroxyglutarate dysregulates the differentiation of human mesenchymal stromal cells via inducing DNA hypermethylation

BMC Cancer, 2021
Background Isocitrate dehydrogenase (IDH1/2) gene mutations are the most frequently observed mutations in cartilaginous tumors. The mutant IDH causes elevation in the levels of R-enantiomer of 2-hydroxylglutarate (R-2HG). Mesenchymal stromal cells (MSCs)
Lizhen Liu, Kaimin Hu, Jingjing Feng, Huafang Wang, Shan Fu, Binsheng Wang, Limengmeng Wang, Yulin Xu, Xiaohong Yu, He Huang   +9 more
doaj   +1 more source

Clinical Characteristics and Prognostic Risk Factors for Pediatric B‐Cell Lymphoblastic Lymphoma: A Multicenter Retrospective Cohort Study for China Net Childhood Lymphoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐cell lymphoblastic lymphoma (B‐LBL) represents a rare variety of non‐Hodgkin lymphoma, with limited research on its biology, progression, and management. Methods A retrospective analysis was performed on the clinical characteristics of 256 patients aged ≤18 years who received treatment under the China Net Childhood Lymphoma (CNCL)‐
Zhijuan Liu, Jian Wang, Ling Jin, Yanlong Duan, Fu Li, Yueping Jia, Leping Zhang, Xiaojun Yuan, Wei Liu, Ying Liu, Ansheng Liu, Mincui Zheng, Yunpeng Dai, Lian Jiang, Lirong Sun, Xiaowen Zhai, Rong Liu, Chunju Zhou, Zifen Gao, Yonghong Zhang, Xiaomei Yang   +20 more
wiley   +1 more source

Dengue virus infection in hematopoietic stem cell transplant recipients: A case series and comparative literature review from dengue endemic region

SAGE Open Medical Case Reports
This case series describes the wide spectrum of clinical presentation, laboratory findings, and morbidity/mortality associated with dengue fever in hematopoietic stem cell transplant recipients, treated in a dengue endemic region.
Waseem Shahani, Faiqa Fayyaz, Shafaq Abdul Samad, Muhammad Nizamuddin, Madiha Abid, Aisha Jamal, Zainab Ghayas, Ayesha Rafiq, Abdul Hayee, Dilnasheen Safdar, Tasleem Farzana, Uzma Zaidi   +11 more
doaj   +1 more source

Metabolic reprogramming in macrophage responses

Biomarker Research, 2021
Macrophages are critical mediators of tissue homeostasis, with the function of tissue development and repair, but also in defense against pathogens. Tumor-associated macrophages (TAMs) are considered as the main component in the tumor microenvironment ...
Yang Liu, Ruyi Xu, Huiyao Gu, Enfan Zhang, Jianwei Qu, Wen Cao, Xi Huang, Haimeng Yan, Jingsong He, Zhen Cai   +9 more
doaj   +1 more source

Mobilized Peripheral Blood Stem Cells Versus Unstimulated Bone Marrow As a Graft Source for T-Cell-Replete Haploidentical Donor Transplantation Using Post-Transplant Cyclophosphamide. [PDF]

, 2017
Purpose T-cell-replete HLA-haploidentical donor hematopoietic transplantation using post-transplant cyclophosphamide was originally described using bone marrow (BM).
Al Malki, Monzr M, Anasetti, Claudio, Argall, Trevor, Bashey, Asad, Ciurea, Stefan O, Eapen, Mary, Fasan, Omotayo, Fuchs, Ephraim Joseph, Gaballa, MD, Sameh, Hamadani, Mehdi, McCurdy, Shannon R, Munshi, Pashna, Nakamura, Ryotaro, O\u27Donnell, Paul V, Perales, Miguel-Angel, Raj, Kavita, Rocha, Vanderson, Romee, Rizwan, Rowley, Scott, Salit, Rachel B, Soiffer, Robert J, Solh, Melhem, St Martin, Andrew, Zhang, Mei-Jie   +23 more
core   +2 more sources

Predicting sinusoidal obstruction syndrome after allogeneic stem cell transplantation with the EASIX biomarker panel [PDF]

, 2020
No biomarker panel is established for prediction of sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD), a major complication of allogeneic stem cell transplantation (alloSCT).
Blau, Igor W., Bullinger, Lars, Dreger, Peter, Jiang, Sihe, Luft, Thomas, Majer-Lauterbach, Joshua, Müller-Tidow, Carsten, Penack, Olaf, Radujkovic, Aleksandar, Schult, David, Terzer, Tobias   +10 more
core   +3 more sources

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Stem Cell Mobilization and Harvesting Failure in Case of Heavily Pretreated Patients

Journal of Interdisciplinary Medicine, 2017
Background: High-dose chemotherapy and autologous stem cell transplantation have become a standard curative treatment in various hematologic malignancies. Many factors can affect the success of mobilization and hematopoietic stem cell harvesting.
Mild Eszter, Lázár Erzsébet, Köpeczi Judit-Beáta, Kakucs Enikő, Găzdac Marius, Pakucs Annamária, Tudor Cezara, Benedek István   +7 more
doaj   +1 more source

Immune Reconstitution-Based Score for Risk Stratification of Chronic Graft-Versus-Host Disease Patients

Frontiers in Oncology, 2021
IntroductionAllogeneic stem cell transplantation survivors are at a relevant risk of developing chronic GvHD (cGvHD), which importantly affects quality of life and increases morbidity and mortality.
Fabio Serpenti, Francesca Lorentino, Francesca Lorentino, Sarah Marktel, Raffaella Milani, Carlo Messina, Raffaella Greco, Stefania Girlanda, Daniela Clerici, Fabio Giglio, Carmine Liberatore, Francesca Farina, Sara Mastaglio, Simona Piemontese, Elena Guggiari, Francesca Lunghi, Magda Marcatti, Matteo G. Carrabba, Massimo Bernardi, Chiara Bonini, Chiara Bonini, Andrea Assanelli, Consuelo Corti, Jacopo Peccatori, Fabio Ciceri, Fabio Ciceri, Maria Teresa Lupo-Stanghellini   +26 more
doaj   +1 more source