Results 41 to 50 of about 356,556 (259)

FREQUENCY OF FMS-LIKE TYROSINE KINASE 3 KINASE DOMAIN POINT MUTATION (FLT3/TKD MUTATION) IN DIFFERENT AGE GROUPS OF ACUTE MYELOID LEUKEMIA PATIENTS.

Mediterranean Journal of Hematology and Infectious Diseases, 2014
Activation of the FLT3 receptor tyrosine kinase, by point mutations in the second tyrosine kinase domain (TKD), has been described in patients with acute myeloid leukemia (AML). This study was planned to estimate the frequency of FMS-like Tyrosine Kinase
Khaleeq unnisa, zeeshan ulqadar, sadaf shahab, Muhammad Nadeem, Danish Zahid, zaen ulAbedin, Saqib Ansari, Tasneem Farzana, Mehwesh Taj, Munira Borhany, Arshi Naz, Tahir Sultan Shamsi   +11 more
doaj  

Immune status of recipients following bone marrow - Augmented solid organ transplantation [PDF]

, 1995
It has been postulated that the resident “passenger” leukocytes of hematolymphoid origin that migrate from whole organ grafts and subsequently establish systemic chimerism are essential for graft acceptance and the induction of donor-specific ...
Banas, R, Carroll, P, Demetris, J, Dodson, F, Fontes, P, Fung, JJ, Lombardozzi, S, Pappo, O, Pavlick, M, Pham, S, Rao, AS, Shapiro, R, Starzl, TE, Trucco, M, Zeevi, A   +14 more
core   +1 more source

New Treatment Methods in Multiple Myeloma

Journal of Interdisciplinary Medicine, 2017
Multiple myeloma accounts for 10% of the hematologic malignancies and is characterized by a single clone of plasma cells producing a monoclonal protein. The aim of this review is to summarize the current treatment methods of multiple myeloma. In the last
Jakab Szende, Lázár Erzsébet, Benedek István, Köpeczi Judit Beáta, Pakucs Annamária, Benedek István   +5 more
doaj   +1 more source

Glia maturation factor-γ is required for initiation and maintenance of hematopoietic stem and progenitor cells

Stem Cell Research & Therapy, 2023
Background In vertebrates, hematopoietic stem and progenitor cells (HSPCs) emerge from hemogenic endothelium in the floor of the dorsal aorta and subsequently migrate to secondary niches where they expand and differentiate into committed lineages.
Honghu Li, Qian Luo, Shuyang Cai, Ruxiu Tie, Ye Meng, Wei Shan, Yulin Xu, Xiangjun Zeng, Pengxu Qian, He Huang   +9 more
doaj   +1 more source

mTOR inhibition improves the immunomodulatory properties of human bone marrow mesenchymal stem cells by inducing COX-2 and PGE2

Stem Cell Research & Therapy, 2017
Background Bone marrow mesenchymal stem cells (MSCs) are promising candidates for the treatment of various inflammatory disorders due to their profound immunomodulatory properties.
Binsheng Wang, Yu Lin, Yongxian Hu, Wei Shan, Senquan Liu, Yulin Xu, Hao Zhang, Shuyang Cai, Xiaohong Yu, Zhen Cai, He Huang   +10 more
doaj   +1 more source

Mobilized Peripheral Blood Stem Cells Versus Unstimulated Bone Marrow As a Graft Source for T-Cell-Replete Haploidentical Donor Transplantation Using Post-Transplant Cyclophosphamide. [PDF]

, 2017
Purpose T-cell-replete HLA-haploidentical donor hematopoietic transplantation using post-transplant cyclophosphamide was originally described using bone marrow (BM).
Al Malki, Monzr M, Anasetti, Claudio, Argall, Trevor, Bashey, Asad, Ciurea, Stefan O, Eapen, Mary, Fasan, Omotayo, Fuchs, Ephraim Joseph, Gaballa, MD, Sameh, Hamadani, Mehdi, McCurdy, Shannon R, Munshi, Pashna, Nakamura, Ryotaro, O\u27Donnell, Paul V, Perales, Miguel-Angel, Raj, Kavita, Rocha, Vanderson, Romee, Rizwan, Rowley, Scott, Salit, Rachel B, Soiffer, Robert J, Solh, Melhem, St Martin, Andrew, Zhang, Mei-Jie   +23 more
core   +2 more sources

Back to the future [PDF]

, 2005
Sin ...
Bach, Barker, Barnard, Billingham, Calne, Calne, Cordier, Dausset, Gatti, Hamburger, Lakkis, Main, Moskophidis, Murray, Przepiorka, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Thomas, Thomas E. Starzl, Webb, Zinkernagel, Zinkernagel, Zinkernagel   +32 more
core   +3 more sources

A pilot study of implication of machine learning for relapse prediction after allogeneic stem cell transplantation in adults with Ph-positive acute lymphoblastic leukemia

Scientific Reports, 2023
The posttransplant relapse in Ph-positive ALL increases the risk of death. There is an unmet need for instruments to predict the risk of relapse and plan prophylaxis. In this study, we analyzed posttransplant data by machine learning algorithms.
Kseniia S. Afanaseva, Evgeny A. Bakin, Anna G. Smirnova, Ildar M. Barkhatov, Tatiana L. Gindina, Ivan S. Moiseev, Sergey N. Bondarenko   +6 more
doaj   +1 more source

Bone Marrow Transplantation in Thalassemia

Hematology/Oncology Clinics of North America, 1991
Since 1983, 350 patients aged 1 to 19 years with beta-homozygous thalassemia were given infusions of HLA-identical marrow after high doses of busulphan and cyclophosphamide. Survival and event-free survival leveled off about 1 year after bone marrow transplantation at 82% and 75%, respectively.
G, Lucarelli, M, Galimberti, P, Polchi, E, Angelucci, D, Baronciani, C, Giardini, S M, Durazzi, F, Agostinelli, C, Giorgi, M, Donati   +9 more
openaire   +3 more sources

Failure in generating hemopoietic stem cells is the primary cause of death from cytomegalovirus disease in the immunocompromised host [PDF]

, 1988
We have shown in a murine model system for cytomegalovirus (CMV) disease in the immunocompromised host that CMV infection interferes with the earliest detectable step in hemopoiesis, the generation of the stem cell CFU-S-I, and thereby prevents the ...
Busch, Friedrich W., Bühring, Hans-Jörg, Koszinowski, Ulrich H., Mutter, Wolfgang, Reddehase, Matthias J.   +4 more
core   +2 more sources