Results 51 to 60 of about 356,556 (259)
Acute myeloid leukemia (AML) is a cancerous disease affecting the myeloid line of the bone marrow cells. FLT3, also known as CD135, is a proto-oncogene, which, if mutated, leads to different types of cancer.
Bzduch Árpád+5 more
doaj +1 more source
Background Myelofibrosis is a myeloproliferative stem cell disorder curable exclusively by allogeneic hematopoietic stem cell transplantation and is associated with substantial mortality and morbidity. The aim of this study was to assess disease-specific
Markus Ditschkowski+6 more
doaj +1 more source
Bone Marrow Transplantation [PDF]
Hematopoietic transplantation is increasingly being used as treatment for a variety of severe diseases. Data from International Registries indicate that more than 25,000 transplants are performed every year in Europe, and a similar number in the United States (US) (Copelan 2006; Gratwohl et al. 2007).
Sierra, Jorge, Franquet, Tomas
openaire +1 more source
Clinical intestinal transplantation: New perspectives and immunologic considerations [PDF]
Background: Although tacrolimus-based immunosuppression has made intestinal transplantation feasible, the risk of the requisite chronic high- dose treatment has inhibited the widespread use of these procedures.
Abu-Elmagd, K+14 more
core +1 more source
Inflammation and Bone Marrow Transplantation
The procedural requirements of bone marrow transplantation (BMT) predispose to the dramatic induction of local and systemic inflammatory states and can be conceived in relation to transplant conditioning, the activation of alloreactive T cells and finally, the effector stage of graft-versus-host disease (GVHD).
openaire +4 more sources
Tetralogy of F allot with Complete D i G eorge Syndrome: Report of a Case and a Review of the Literature [PDF]
Complete D i G eorge syndrome ( CDGS ) has a severe T ‐cell immunodeficiency and is fatal without thymus or bone marrow transplantation. Associated congenital heart disease ( CHD ) further complicates the clinical management.
Humes, Richard A.+2 more
core +1 more source
Dose-adapted post-transplant cyclophosphamide for HLA-haploidentical transplantation in Fanconi anemia. [PDF]
We developed a haploidentical transplantation protocol with post-transplant cyclophosphamide (CY) for in vivo T-cell depletion (TCD) using a novel adapted-dosing schedule (25 mg/kg on days +3 and +4) for Fanconi anemia (FA).
Bonfim, C+8 more
core +2 more sources