Results 21 to 30 of about 2,226,476 (263)
Bone contributes to supporting the body, protecting the central nervous system and other organs, hematopoiesis, the regulation of mineral metabolism (mainly calcium and phosphate), and assists in respiration. Bone has many functions in the body. Recently,
Yuichi Takashi, Daiji Kawanami
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Background Late-stage breast cancer preferentially metastasises to bone; despite advances in targeted therapies, this condition remains incurable.
Diane Lefley +11 more
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Osteoporosis, characterized by the destruction of bone resorption and bone formation, is a serious disease that endangers human health. Osteoporosis prevention and treatment has become one of the important research contents in the field of medicine ...
Xiao Lin +10 more
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Background Single-cell RNA sequencing (scRNA-seq) provides valuable insights into human islet cell types and their corresponding stable gene expression profiles. However, this approach requires cell dissociation that complicates its utility in vivo.
Randy B. Kang +9 more
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Bacterial lipopolysaccharide potentiates type II collagen-induced arthritis in mice
Collagen-induced arthritis (CIA) is an immunologically relevant animal model of human rheumatoid arthritis. Studies comparing the disease incidence in genetically susceptible male and female DBA/1LacJ mice demonstrated that under low density/low stress ...
Robert G. Caccese +2 more
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Subchronic dietary exposure of rats to cadmium alters the metabolism of metals essential to bone health [PDF]
Cadmium (Cd) was recently identified as a risk factor for osteoporosis. Skeletal damage may be the critical effect of low-level long-term exposure to Cd in the general population exposed via food, but the mechanisms behind this are not clearly understood.
M Kolf-Clauw +5 more
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Bone tissue infection is a major clinical challenge with high morbidity and a significant healthcare burden. Therapeutic approaches are usually based on systemic antibacterial therapies, despite the potential adverse effects associated with antibiotic ...
Lorena Castro Mariano +2 more
doaj +1 more source
Role of cancer stem cells in the development of giant cell tumor of bone
The primary bone tumor is usually observed in adolescence age group which has been shown to be part of nearly 20% of the sarcomas known today. Giant cell tumor of bone (GCTB) can be benign as well as malignant tumor which exhibits localized dynamism and ...
Abdul Rouf War +7 more
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Objectives Assessment of the disease acceptance level in women with osteoporosis depending on selected sociodemographic factors. Material and Methods The study included a group of 198 women, aged M±SD 72.3±8.59 years, diagnosed with postmenopausal ...
Bogumiła Górczewska +1 more
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The influence of growth hormone deficiency on bone health and metabolism
Growth hormone (GH) is a key peptide hormone in the regulation of bone metabolism, through its systemic and paracrine action mediated directly as well as by insulin-like growth factor-1 (IGF-1).
Jakub Wydra +3 more
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