Results 1 to 10 of about 2,167,273 (278)

Bone metastases

Nature Reviews Disease Primers, 2020
Bone is the most frequent site for metastasis for many cancers, notably for tumours originating in the breast and the prostate. Tumour cells can escape from the primary tumour site and colonize the bone microenvironment. Within the bone, these disseminated tumour cells, as well as those arising in the context of multiple myeloma, may assume a state of ...
Robert E Coleman, Peter I Croucher, Anwar R Padhani, Philippe Clézardin, Edward Chow, Marie Fallon, Theresa Guise, Simone Colangeli, Rodolfo Capanna, Luis Costa   +9 more
semanticscholar   +10 more sources

Editorial: Bone Metastases [PDF]

Frontiers in Oncology, 2021
No abstract ...
Valenti, Maria Teresa, Mottes, Monica, Dalle Carbonare, Luca, Feron, Olivier   +3 more
openaire   +4 more sources

Semaphorin 4D Promotes Skeletal Metastasis in Breast Cancer. [PDF]

, 2016
Bone density is controlled by interactions between osteoclasts, which resorb bone, and osteoblasts, which deposit it. The semaphorins and their receptors, the plexins, originally shown to function in the immune system and to provide chemotactic cues for ...
Basile, John R, Bugshan, Amr, Buhamrah, Asma, Lin, Yi-Ling, Schneider, Abraham, Yang, Ying-Hua, Zhou, Hua   +6 more
core   +14 more sources

Potential biomarkers for the early detection of bone metastases

Frontiers in Oncology, 2023
The clinical manifestations of bone metastases are diversified while many sites remain asymptomatic at early stage. As the early diagnosis method is not perfect and the early symptoms of tumor bone metastasis are not typical, bone metastasis is not easy ...
Yang Hao, Yang Hao, Feifan Zhang, Feifan Zhang, Yan Ma, Yage Luo, Yongyong Zhang, Ning Yang, Man Liu, Hongjian Liu, Jitian Li, Jitian Li, Jitian Li   +12 more
doaj   +1 more source

A Simple Scoring System Predicting the Survival Time of Patients with Bone Metastases after RT. [PDF]

PLoS ONE, 2016
This study aimed to develop a scoring system to predict the survival time of patients with bone metastases after radiation therapy (RT). The scoring system can guide physicians to a better selection of appropriate treatment regimens.The medical records ...
Wen-Yi Zhang, Hui-Fang Li, Meng Su, Rui-Fang Lin, Xing-Xing Chen, Ping Zhang, Chang-Lin Zou   +6 more
doaj   +1 more source

Distribution Features of Skeletal Metastases: A Comparative Study between Pulmonary and Prostate Cancers. [PDF]

PLoS ONE, 2015
Bone scintigraphies are widely applied for detecting bone metastases. The aim of this study was to investigate distribution features of bone metastases in pulmonary and prostate cancers.
Changyin Wang, Ying Shen, Shaobo Zhu
doaj   +1 more source

Local surgical complication rates in patients receiving surgery without immediate post-operative radiation therapy for lower extremity bone metastases

Journal of Bone Oncology, 2020
Purpose: Pathological metastatic fractures in lower-extremity weight bearing bones often require surgical reconstruction. Post-operative radiation is routinely recommended following surgical reconstruction.
William Pidduck, Leah Drost, Albert Yee, Edward Chow, Ravi Tuazon, Patrick Henry   +5 more
doaj   +1 more source

Incidence of Bone Metastases and Skeletal-Related Events in Patients With EGFR-Mutated NSCLC Treated With Osimertinib

JTO Clinical and Research Reports, 2023
Introduction: Bone metastases are frequent in patients with EGFR-mutated (EGFR+) NSCLC. Skeletal-related events (SREs) are common in these patients; however, no data on SRE in osimertinib-treated patients are reported.
Anita J.W. M. Brouns, MD, Ard van Veelen, MSc, G. D. Marijn Veerman, MD, Christi Steendam, MD, Safiye Dursun, MD, Cor van der Leest, PhD, Sander Croes, PhD, Anne-Marie C. Dingemans, MD, PhD, Lizza E.L. Hendriks, PhD   +8 more
doaj   +1 more source

Prevalence and prognosis of bone metastases in common solid cancers at initial diagnosis: a population-based study

BMJ Open, 2023
Objective Bone is one of the most common target sites for advanced tumours. The objective was to survey the prevalence and prognosis of bone metastases in 12 common solid malignant tumours.Design A retrospective cohort study.Methods A total of 1 425 332 ...
Jing Zhang, Dongfeng Cai, Song Hong
doaj   +1 more source

Advances in Treatment of Patients with Prostate Cancer Bone Metastases

Zhongliu Fangzhi Yanjiu, 2020
The incidence of bone metastases is relatively high in prostate cancer (PCa) patients. Bone metastases not only cause pain and increase the risk of skeletal related events (SREs), but also have a significant impact on quality of life and shorten the ...
LI Ning, XIAO Guoyou
doaj   +1 more source