Results 101 to 110 of about 1,181,357 (307)
Advanced Science, EarlyView.Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu +10 more
wiley +1 more source
Progress in the clinical use of radiotherapy for bone metastasis in breast cancer
Zhongguo aizheng zazhi, 2016 Bone remains the predominant site of metastasis in advanced breast cancer. Bone metastases dramatically decrease the quality of life. Moreover, pathologic fractures and other skeletal-related events (SREs) caused by bone metastases could result in higher
胡群超, 俞晓立, 郭小毛
doaj
Optimal management of bone metastases in breast cancer patients
, 2011 MH Wong, N PavlakisDepartment of Medical Oncology, Royal North Shore Hospital, Sydney, NSW, AustraliaAbstract: Bone metastasis in breast cancer is a significant clinical problem.
Pavlakis N, Wong MH
core
Advanced Science, EarlyView.A nanobiohybrid vaccine was designed by constructing a hydrogen‐bonded organic framework coencapsulated with glucose oxidase (GOx) and tumor antigens. This nanobiohybrid vaccine executed a GOx‐catalyzed enzyme reaction that disrupted glucose metabolism and induced redox imbalance in dendritic cells, leading to autophagy‐dependent antigen cross ...
Weidong Wang +5 more
wiley +1 more source
Advanced Science, EarlyView.We developed an ultrasound‐controlled biomimetic nanoplatform, mRNA/V@M NPs, to co‐deliver CD74 mRNA and V‐9302 for fibrotic TNBC therapy. CD74 mRNA reprograms myCAFs into antigen‐presenting apCAF cells through the CD74‐MHC II pathway, while V‐9302 induces ICD and activates MHC I‐CD8+ T cell immunity.
Chen Ai +9 more
wiley +1 more source
Targeted Treatments of Bone Metastases in Patients with Lung Cancer
Frontiers in Oncology, 2014 Until now approximately 30-40% of patients with advanced lung cancer develop bone metastases, but as the newer therapies are extending survival, the chance of developing bone metastases increases.Bone metastases cause skeletal-related events (SREs) such ...
Vera eHirsh
doaj +1 more source
, 2013 Bone pain due to skeletal metastases constitutes the most common type of chronic pain among patients with cancer. Almost 65 % of patients with prostate or breast cancer and 35 % of those with advanced lung, thyroid and kidney cancers will have ...
Fabio M. Paes, Paes, Fabio M.
core +1 more source
Engineering‐Modulated Molybdenum Enzymes Strategy for Tumor‐Specific Metabolic‐Immunotherapy
Advanced Science, EarlyView.Biodegradable molybdenum sulfide nanoparticles were synthesized via a one‐pot strategy to increase molybdenum enzyme activity and thus effectively potentiate anti‐tumor immunity by integrating molybdenum‐based metalloimmunotherapy with hydrogen sulfide gas therapy.
Xiaoxiao Pan +14 more
wiley +1 more source
What defines 'cure' after liver resection for colorectal metastases? Results after 10 years of follow-up [PDF]
, 2010 Background: During the last two decades, resection of colorectal liver metastases (CLM) in selected patients has become the standard of care, with 5-year survival rates of 25-58%.
Parks, Rowan W.; id_orcid +8 more
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Advanced Science, EarlyView.Rigidity‐tunable nanovesicle (P‐Pm) with mechanically induced adjuvanticity toward tumor‐associated macrophages (TAMs) was designed to engineer R848/gp100 antigen ‐loaded nanovaccine (P@Rg‐Pm), which achieved outstanding anti‐tumor outcomes in both therapeutic and preventive model of B16‐F10 melanoma.
Bangyue Luo, Liyan Qiu
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