Results 11 to 20 of about 2,167,273 (278)
Sclerostin inhibition alleviates breast cancer-induced bone metastases and muscle weakness [PDF]
JCI Insight, 2019 Breast cancer bone metastases often cause a debilitating non-curable condition with osteolytic lesions, muscle weakness and a high mortality. Current treatment comprises chemotherapy, irradiation, surgery and anti-resorptive drugs that restrict but do ...
Brandt, Diana +5 more
core +2 more sources
Incidence, prevalence, and outcomes of systemic malignancy with bone metastases
Journal of Orthopaedic Surgery, 2020 Purpose: Evidence on the incidence, prevalence, and outcomes of bone metastases among patients with systemic malignancy is limited. This study aimed to evaluate it using the Surveillance, Epidemiology, and End Results (SEER) database.
Wenli Jiang +5 more
doaj +2 more sources
Oncology Reviews, 2017 Bone is a frequent site of metastases and typically indicates a short-term prognosis in cancer patients. Once cancer has spread to the bones it can rarely be cured, but often it can still be treated to slow its growth. The majority of skeletal metastases are due to breast and prostate cancer.
Filipa Macedo +6 more
openaire +4 more sources
Clinical and Translational Medicine, 2019 Background Bone is a preferential site for prostate cancer (PCa) metastasis. However, sites of synchronous distant metastases in PCa patients with bone metastases at initial diagnosis and their impacts on prognosis are still unclear, limiting our ability
Feng Zhao +8 more
doaj +2 more sources
Quantitative bone SPECT/CT: high specificity for identification of prostate cancer bone metastases
BMC Musculoskeletal Disorders, 2019 Purpose Bone scintigraphy with 99mTc-labeled diphosphonates can identify prostate cancer bone metastases with high sensitivity, but relatively low specificity, because benign conditions such as osteoarthritis can also trigger osteoblastic reactions.
Flavian Tabotta +5 more
doaj +2 more sources
Serum calcium, alkaline phosphotase and hemoglobin as risk factors for bone metastases in bladder cancer. [PDF]
PLoS ONE, 2017 Early detection of bone metastases is helpful for the treatment of bladder cancer (BC). In this study, we investigated the potential risk factors for bone metastasis in newly diagnosed patients with BC.
Ping Huang +7 more
doaj +2 more sources
JAMA Oncology, 2022 Importance To our knowledge, there have been no clinical trials of ultra-high-dose-rate radiotherapy delivered at more than 40 Gy/sec, known as FLASH therapy, nor first-in-human use of proton FLASH.
A. Mascia +17 more
semanticscholar +1 more source
JCO Oncology Practice, 2022 PURPOSE: Exercise has been underutilized in people with advanced or incurable cancer despite the potential to improve physical function and reduce psychosocial morbidity, especially for people with bone metastases because of concerns over skeletal ...
K. Campbell +21 more
semanticscholar +1 more source
Mechanisms, Diagnosis and Treatment of Bone Metastases
Cells, 2021 Bone and bone marrow are among the most frequent metastatic sites of cancer. The occurrence of bone metastasis is frequently associated with a dismal disease outcome.
J. Ban, V. Fock, D. Aryee, H. Kovar
semanticscholar +1 more source
Journal of Bone and Mineral Research, 2022 Immunotherapies use components of the immune system, such as T cells, to fight cancer cells, and are changing cancer treatment, causing durable responses in some patients.
Danna L. Arellano +10 more
semanticscholar +1 more source