Results 111 to 120 of about 379,930 (351)
Sculpting the Future of Bone: The Evolution of Absorbable Materials in Orthopedics
Advanced Materials, EarlyView.This review summarizes the current status of polymeric, ceramic, and metallic absorbable materials in orthopedic applications, and highlights several innovative strategies designed to enhance mechanical performance, control degradation, and promote bioactivity. We also discuss the progress and translational potential of absorbable materials in treating
Zhao Wang +13 more
wiley +1 more source
Predictive Role of Elevated Neutrophil-Lymphocyte Ratio for Bone Metastasis in Esophageal Cancer
Technology in Cancer Research & TreatmentPurpose Research on bone metastasis in esophageal cancer (EC) is relatively limited. Once bone metastasis occurs in patients, their prognosis is poor, and it severely affects their quality of life.
Xuan Wang PhD +9 more
doaj +1 more source
FUS-CHOP promotes invasion in myxoid liposarcoma through a SRC/FAK/RHO/ROCK-dependent pathway [PDF]
, 2017 Deregulated SRC/FAK signaling leads to enhanced migration and invasion in many types of tumors. In myxoid and round cell liposarcoma (MRCLS), an adipocytic tumor characterized by the expression of the fusion oncogene FUS-CHOP, SRC have been found as one ...
González, M. Victoria +3 more
core +2 more sources
Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects
Advanced Materials, EarlyView.Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley +1 more source
Macrophage heterogeneity in bone metastasis
Journal of Bone OncologyPrevious studies illustrated that macrophage, a type of innate immune cell, plays critical roles in tumour progression and metastasis. Bone is the most frequent site of metastasis for several cancer types including breast, prostate, and lung.
Jingxuan Guo, Ruo-Yu Ma, Bin-Zhi Qian
doaj +1 more source
Orthopedics & Traumatology, 1995 全身骨転移中約30%を占めると言われている骨盤骨転移の実態は明らかではない. 当科受診患者中, 骨盤部に骨転移を確認できた62症例について年齢・性別・症状・転移部位・原発腫瘍の種類・予後などを調査した. 全62例, 男性42例女性20例, 20歳から84歳平均59.2歳. 初診時の症状は, 腰痛, 下肢痛で約5割を占め, 転移部位は腸骨部に約50%が集中していた. 原発腫瘍を検索したところ前立腺癌, 肺癌, 直腸癌で約50%であった. また骨盤内臓器からの転移例は25例 (47.2%) と高率であった. 初診時原発病巣不明であったものの55.2%は骨盤内原発であり, 肺原発を加えると80%を越える. 予後は前立腺癌のみが平均2年以上の生存期間を有す他は, 平均半年から1年と予後不良であった.
Masatoshi Yamada +4 more
openaire +2 more sources
Hydrogel Confinement Strategies for 3D Cell Culture in Microfluidic Systems
Advanced Materials Technologies, EarlyView.Hydrogel confinement structures are key to organizing 3D cell cultures in microfluidic devices. This review classifies five structural strategies (micropillar, phaseguide, porous membrane, stepped‐height, and support‐free) and examines their trade‐offs alongside fabrication methods.
Soohyun Kim, Min Seok Lee, Sung Kyun Lee
wiley +1 more source
Metastasis and circulating tumor cells [PDF]
, 2012 Cancer is a prominent cause of death worldwide. In most cases, it is not the primary tumor which causes death, but the metastases. Metastatic tumors are spread over the entire human body and are more difficult to remove or treat than the primary tumor ...
Dalum, G. van +2 more
core +1 more source
Progress and Prospects of Persistent Luminescent Nanocrystals in Biomedical Applications
Advanced Optical Materials, EarlyView.This review summarizes recent progress in materials‐level control of persistent luminescence, including mechanistic understanding, wavelength/intensity tuning, and activation strategies, as well as emerging biomedical applications in imaging, biosensing, cell tracking, optogenetic stimulation, and biophotochemical activation.
Peng Pei +5 more
wiley +1 more source